Relationship between physical exercise and COVID-19 (SARS-CoV-2): systematic review

Sport Sciences for Health, Journal Year: 2023, Volume and Issue: 19(1), P. 55 - 67

Published: Jan. 7, 2023

Language: Английский

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Effects of physical activity on the severity of illness and mortality in COVID-19 patients: A systematic review and meta-analysis

Frontiers in Physiology, Journal Year: 2022, Volume and Issue: 13

Published: Nov. 8, 2022

Purpose: This systematic review and meta-analysis investigated the association between Physical activity (PA) before Coronavirus Disease 2019 (COVID-19) infection severity of illness mortality in COVID-19 patients. Methods: A comprehensive search was undertaken to identify retrospective nonrandomized controlled trial studies comparing among patients who had previously reported their participation PA with those not. The databases searched were PubMed, Cochrane Library, Scopus, Science Direct, EMBASE, OPENGREY.EU, ClinicalTrials.gov. risk bias assessed using Newcastle-Ottawa Scale. random-effects model used for determining pairwise meta-analyses. protocol registered PROSPERO (CRD42021262548). Results: Eighteen met inclusion criteria (5 cross-sectional, 12 cohort, 1 case-control studies). All 618 680 subjects adults. significantly decreased death (odds ratio [OR] 0.34; 95% confidence interval [CI], 0.19-0.62; p < 0.001) severe outcomes (OR 0.60; CI, 0.48-0.76; 0.001). Subgroup analysis showed that ≥150 min/wk at a moderate intensity or ≥75 vigorous reduced risks mortality. Vigorous risk, whereas Conclusion: might reduce patients, especially ≥ 150 activity. However, careful interpretations should be considered due difference patterns definitions included studies. finding implies engaging regular PA, even different patterns, has beneficial effects on

Language: Английский

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Being fit in the COVID-19 era and future epidemics prevention: Importance of cardiopulmonary exercise test in fitness evaluation

Progress in Cardiovascular Diseases, Journal Year: 2024, Volume and Issue: 83, P. 84 - 91

Published: March 1, 2024

Language: Английский

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The role of physical activity in the clinical outcomes of people diagnosed with Covid-19: A systematic review

JSAMS Plus, Journal Year: 2022, Volume and Issue: 1, P. 100007 - 100007

Published: Oct. 1, 2022

This review aimed to compile the evidence on PA and clinical outcomes of people receiving a positive diagnosis covid-19. Systematic review. The search was performed in five databases: EMBASE, MEDLINE via PubMed portal, Scopus, SPORTDiscus EBSCO platform, Web Science. In addition, "gray" literature searched through Google Scholar medRxiv published between January 2020 July 2022. Studies were assessed for risk bias, with extraction relevant data. Our revealed total 10,028 studies. After applying eligibility criteria 32 studies included. Thirty-one at low moderate bias. Physically active individuals, who diagnosed covid-19, presented attenuation outcomes, such as decreased hospitalization, recovery time, number symptoms, severity, ICU death when compared individuals levels or classified sedentary. covid-19 may have several related including but not limited hospitalization symptoms. Public health authorities should develop strategies initiatives that promote safe environments improve prognosis Open Science Framework (OSF), DOI registry 10.17605/OSF.IO/PV6NF. It can be consulted access link: https://doi.org/10.17605/OSF.IO/PV6NF, October 07, 2021.

Language: Английский

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Association of physical activity and the risk of COVID-19 hospitalization: A dose–response meta-analysis

Medicine, Journal Year: 2023, Volume and Issue: 102(4), P. e32814 - e32814

Published: Jan. 27, 2023

Background: Many people have experienced a high burden due to the spread of coronavirus disease (COVID-19) and its serious consequences for health everyday life. Prior studies reported that physical activity (PA) may lower risk COVID-19 hospitalization. The present meta-analysis explored dose–response relationship between PA Methods: Epidemiological observational on hospitalization were included. Categorical relationships assessed using random effect models. Robust error meta-regression models continuous (metabolic equivalent [Met]-h/wk) across reporting quantitative estimates. Results: Seventeen (cohort\case–control\cross-section) met criteria inclusion in meta-analysis. dose-relationship analysis showed 40% (risk ratio [RR] 0.60, 95% confidence interval [CI]: 0.48–0.71) reduction compared lowest dose PA. results non-linear inverse (P non-linearity < .05) When total was or >10 Met-h/wk, an increase 4 Met-h/wk associated with 14% (RR = 0.83, CI: 0.85–0.87) 11% 0.89, 0.87–0.90) hospitalization, respectively. Conclusions: There level Doses guideline-recommended minimum levels by World Health Organization be required more substantial reductions risk.

Language: Английский

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The effects of the first wave of COVID-19 restrictions on physical activity: a longitudinal study from “step into health” program in Qatar

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: March 6, 2024

The COVID-19 pandemic led to restrictions that prevented physical activity in public places. This study sought conduct a comprehensive longitudinal analysis of how lockdown policies an Arabian Gulf country influenced the patterns during first wave.

Language: Английский

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COVID-19 symptoms and obesity in Korean airline crew

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 2, 2024

Background We aimed to investigate the differences in coronavirus disease 2019 (COVID-19) symptoms according weight among flight and cabin attendants Korea.Methods This study was designed as a cross-sectional survey, comprising 180 airline crew members.Results Out of participants, 22 participants had no at onset. Among 158 who experienced symptoms, most common ones were fatigue (79.7%), cough (63.9%), myalgia (63.3%). Participants did not currently smoke drank less than once month reported more COVID-19. The number COVID-19 significantly higher with normal compared those overweight/obese (p = .004). time taken return duties after completing treatment longer for .041).Conclusion Airlines should make efforts manage members infected Additionally, smoking have an impact on severity young people; therefore, continuous management is necessary, even if small.

Language: Английский

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Smoking behaviors, physical activities, pulmonary diseases and COVID-19 severity: A Mendelian randomization study

Medicine, Journal Year: 2024, Volume and Issue: 103(34), P. e39416 - e39416

Published: Aug. 23, 2024

Smoking behaviors, physical activities, and pulmonary diseases have been revealed to be associated with COVID-19 severity through observational research. The possible causative effect remains undetermined. To investigate this, we thus carried out a Mendelian randomization (MR) analysis. We chose genetic variants from genome-wide association studies that are strongly linked 5 exposures related smoking, 1 exposure drinking, 3 levels of activity, diseases. Host Genetics Initiative provided summary-level data for severe (13,769 cases 1,072,442 noncases), hospitalized (32,519 2,062,805 susceptibility (122,616 2,475,240 noncases). Univariate multivariate MR analyses were out. Significant associations found between cigarette smoking per day (OR = 1.357, 95% CI: 1.087-1.694), lifetime index 2.277, 1.602-3.325), interstitial lung disease 1.23, 1.112-1.362), 2.199, 1.738-2.781), initiation 1.419, 1.230-1.637), 1.146, 1.082-1.214), as well 1.39, 1.252-1.543), 1.235, 1.163-1.311), duration vigorous activity 0.733, 0.574-0.935). Duration was suggestively inversely 0.434, 0.221-0.853) 0.323, 0.123-0.850). remained consistent COVID-19, in multivariable Genetic liability mediated the effects on risk (21.0%) (14.4%). This study identified several day, may causally severity.

Language: Английский

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T Cell Peptide Prediction, Immune Response, and Host–Pathogen Relationship in Vaccinated and Recovered from Mild COVID-19 Subjects

Biomolecules, Journal Year: 2024, Volume and Issue: 14(10), P. 1217 - 1217

Published: Sept. 26, 2024

COVID-19 remains a significant threat, particularly to vulnerable populations. The emergence of new variants necessitates the development treatments and vaccines that induce both humoral cellular immunity. This study aimed identify potentially immunogenic SARS-CoV-2 peptides explore intricate host–pathogen interactions involving peripheral immune responses, memory profiles, various demographic, clinical, lifestyle factors. Using in silico experimental methods, we identified several CD8-restricted are either poorly studied or have previously unreported immunogenicity: fifteen from Spike three each non-structural proteins Nsp1-2-3-16. A peptide, LA-9, demonstrated 57% response rate ELISpot assays using PBMCs 14 HLA-A*02:01 positive, vaccinated, mild-COVID-19 recovered subjects, indicating its potential for diagnostics, research, multi-epitope vaccine platforms. We also found younger individuals, with fewer doses longer intervals since infection, showed lower anti-Spike (ELISA) anti-Wuhan neutralizing antibodies (pseudovirus assay), higher naïve T cells, central memory, effector CD4hiCD8low cells (flow cytometry) compared older subjects. In our cohort, prevalence Vδ2-γδ DN CD8 seemed correlate strong anti-NP antibody responses associate Omicron absence confusional state, habitual sporting activity.

Language: Английский

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Does Physical Activity Affect Clinical Symptoms and the Quality of Life of Mild-Infected Individuals with COVID-19 in China? A Cross-Sectional Study

Healthcare, Journal Year: 2023, Volume and Issue: 11(15), P. 2163 - 2163

Published: July 30, 2023

Few studies have identified the links between physical activity (PA), clinical symptoms, and quality of life (QoL) among mildly infected individuals with COVID-19. This cross-sectional study aims to evaluate how PA levels before infections affect infectious symptoms QoL in patients An online questionnaire link including participants' sociodemographic anthropometric characteristics, during COVID-19 period, worst symptomatic day, last seven days was disclosed. Logistic regression multiple linear analyses were applied assess relationships COVID-19-related outcomes. The level statistical significance set at p < 0.05. Compared low-PA-level group, moderate-PA-level group presented a higher risk headaches (OR = 1.34, 95% CI 1.03 1.75, 0.03) high-PA-level muscle/body aches 1.42, 1.04 1.93, 0.03). adjusted analysis showed that no associations found index value on day (moderate-PA-level group: β -0.04, 0.08; 0.17). However, for mobility usual activities dimensions EQ-5D-5L, lower-PA-level had lower burden than higher-PA-level did worst-symptomatic day. Among COVID-19, is associated experiencing QoL.

Language: Английский

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