COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e54769 - e54769

Published: April 30, 2024

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization.

Language: Английский

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Uptake of Recommended Vaccines During Pregnancy Among Publicly and Privately Insured People in the United States, December 2020–September 2022

American Journal of Public Health, Journal Year: 2025, Volume and Issue: unknown, P. e1 - e10

Published: Jan. 23, 2025

Objectives. To estimate maternal COVID-19, influenza, and pertussis vaccine uptake during pregnancy by insurance type identify factors characterizing those vaccinated unvaccinated. Methods. We conducted a US cohort study of pregnant individuals (for pregnancies ending December 11, 2020–September 30, 2022) using claims data. calculated vaccination probability Kaplan-Meier methods identified associated with through binomial regression inverse weights. Results. Among 695 887 (median age = 32 years for privately 27 publicly insured), the cumulative COVID-19 was 43.0% (privately insured) 11.8% (publicly insured). observed marked disparities between influenza (33.2% vs 14.2%) (70.3% 42.8%) vaccination. Only 6.8% 1.1% received all 3 vaccines. odds were lower among drug tobacco users. People high-risk medical conditions, particularly insured, commonly vaccinated. Conclusions. Marked exist insured people. Understanding structural barriers, Medicaid enrollees, is critical to improving access. ( Am J Public Health. Published online ahead print January 23, 2025:e1–e10. https://doi.org/10.2105/AJPH.2024.307899 )

Language: Английский

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Prospective Attitudes towards Respiratory Syncytial Virus (RSV) Vaccination: Validation of a Survey Instrument among Young Females in Jordan Pending Vaccine Authorization

Vaccines, Journal Year: 2023, Volume and Issue: 11(8), P. 1386 - 1386

Published: Aug. 19, 2023

In May 2023, the U.S. FDA advisors endorsed Pfizer's pregnancy-administered vaccine (branded ABRYSVO) to protect infants from respiratory syncytial virus (RSV) infection. Vaccination can reduce burden of RSV-related disease, with previous studies showing its substantial medical and financial in Jordan. However, pregnant women may exhibit hesitancy get vaccinated due concerns about potential risks themselves or their fetuses. This study aimed assess acceptance RSV among young females identify determinants influencing decision using a newly constructed instrument. A survey instrument was developed validated, comprising 26 items measure acceptance. cross-sectional design employed, data collection sample aged 18 45 residing Jordan during 5-6 July convenient approach via an online distributed questionnaire. The final comprised 315 respondents, 67.6% who have heard before study. If safe, effective, provided freely, 70.2% showed willingness vaccine, 15.2% resisted, 14.6% were hesitant. Principal component analysis identified six internally consistent sub-scales following suggested themes: Advice, Burden, Conspiracy, Dangers, Efficiency, Fear, 21 collectively as assigned "ABCDEF" scale for this associated advice fear constructs. validated successfully captured important females. promotion efforts should focus on following: enhancing education, improving trust healthcare institutions providers, reducing burdens through resolving cost issues focusing role social support, addressing safety concerns, tailoring communication strategies effectively promote benefits vaccine. These insights inform public health policies interventions aiming vaccination mitigate diseases infants. Follow-up are recommended target group attitude towards confirm validity conceived ABCDEF

Language: Английский

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A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV

Nature Human Behaviour, Journal Year: 2023, Volume and Issue: 8(1), P. 100 - 114

Published: Oct. 30, 2023

People living with HIV (PLHIV) are at higher risk of poor outcomes SARS-CoV-2 infection. Here we report the pooled prevalence COVID-19 vaccine acceptance/uptake and determinants among this vulnerable population PLHIV based on a systematic review meta-analysis studies published by 25 August 2023. Among 54 included (N = 167,485 participants), 53 166,455) provided data acceptance rate, while 27 150,926) uptake data. The global prevalences were 67.0% 56.6%, respectively. Acceptance rates 86.6% 90.1% for European Region, 74.9% 71.6% Region Americas, 62.3% 78.9% South-East Asian 64.6% 19.3% Eastern Mediterranean 58.0% 35.5% African 57.4% 44.0% Western Pacific Region. rate increased from 65.9% in 2020 to 71.0% 2022, 55.9% 2021 58.1% 2022. Men, aged ≥40 years those who had recently received influenza more likely accept receive vaccine. Factors associated lower Black race, other races (Latinx/Hispanic/mixed race), low education level being unemployed. Vaccine-related factors belief effectiveness, trust, perceived high susceptibility infection fear potential effect PLHIV. Sustained efforts targeted interventions needed reduce regional disparities

Language: Английский

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Effectiveness and safety of COVID-19 vaccines on maternal and perinatal outcomes: a systematic review and meta-analysis

BMJ Global Health, Journal Year: 2024, Volume and Issue: 9(4), P. e014247 - e014247

Published: April 1, 2024

Objective To assess the effects of COVID-19 vaccines in women before or during pregnancy on SARS-CoV-2 infection-related, pregnancy, offspring and reactogenicity outcomes. Design Systematic review meta-analysis. Data sources Major databases between December 2019 January 2023. Study selection Nine pairs reviewers contributed to study selection. We included test-negative designs, comparative cohorts randomised trials infection-related Non-comparative cohort studies reporting outcomes were also included. Quality assessment, data extraction analysis Two independently assessed quality extracted data. undertook random-effects meta-analysis reported findings as HRs, risk ratios (RRs), ORs rates with 95% CIs. Results Sixty-seven (1 813 947 women) Overall, design studies, pregnant fully vaccinated any vaccine had 61% reduced odds infection (OR 0.39, CI 0.21 0.75; 4 23 927 women; I 2 =87.2%) 94% hospital admission 0.06, 0.01 0.71; 868 =92%). In adjusted hypertensive disorders was by 12% (RR 0.88, 0.82 0.92; studies; 115 085 women), while caesarean section 9% 0.91, 0.85 0.98; 6 30 192 women). observed an 8% reduction neonatal intensive care unit 0.92, 0.87 0.97; 54 569 babies born versus not women. general, vaccination associated increased adverse perinatal Pain at injection site most common side effect (77%, 52% 94%; 11 27 195 Conclusion are effective preventing related complications PROSPERO registration number CRD42020178076.

Language: Английский

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COVID-19 Vaccine Acceptance and Hesitancy among People Living with HIV: Review and Meta-Analysis

AIDS and Behavior, Journal Year: 2024, Volume and Issue: 28(7), P. 2193 - 2204

Published: May 7, 2024

Language: Английский

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Association of Infection with Different SARS-CoV-2 Variants during Pregnancy with Maternal and Perinatal Outcomes: A Systematic Review and Meta-Analysis

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(23), P. 15932 - 15932

Published: Nov. 29, 2022

The aim of this study is to review the currently available data, and explore association infection with different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants during pregnancy maternal perinatal outcomes in real world. Observational cohort studies were analyzed that described SARS-CoV-2 pregnancy. Random-effects inverse-variance models used evaluate pooled prevalence (PP) its 95% confidence interval (CI) for outcomes. Random effects estimate odds ratios (OR) their CI between Delta pre-Delta periods, Omicron periods. Eighteen studies, involving a total 133,058 cases (99,567 wild type or pre-variant 33,494 variant infections), included meta-analysis. Among pregnant women infections, PPs required support, critical illness, intensive care unit (ICU) admission, death, preterm birth <37 weeks were, respectively, 27.24% (95%CI, 20.51−33.97%), 24.96% 15.96−33.96%), 11.31% 4.00−18.61%), 4.20% 1.43−6.97%), 33.85% 21.54−46.17%) period, which higher than those while corresponding 10.74% 6.05−15.46%), 11.99% 6.23−17.74%), 4.17% 1.53−6.80%), 0.63% 0.05−1.20%), 18.58% 9.52−27.65%). ICU admission 2.63% 0.98−4.28%), 1.11% 0.29−1.94%), 1.83% 0.85−2.81%) lower These results suggest infections are associated less neonatal adverse outcomes, though need did also occur infections. Since predominant strain globally, has highest rates transmission, it still important remain vigilant protecting vulnerable populations mothers infants. In particular, obstetricians gynecologists should not ignore risks births patients order protect health

Language: Английский

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Acceptance of recommended vaccinations during pregnancy: a cross-sectional study in Southern Italy

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: May 12, 2023

Vaccine administration is a recommended, safe, and effective measure to protect pregnant women against vaccine-preventable diseases (VPDs). Despite available guidance, maternal immunization rates for vaccination influenza with the reduced antigen content tetanus-diphtheria-acellular pertussis vaccine (Tdap) in Italy remain incredibly low. The primary goal of study was explore what Italian knew about VPDs during pregnancy factors affected their decision be vaccinated.This cross-sectional took place between October 2021 April 2022 Southern part Italy. All consecutive women, from those attending selected facilities on randomly days, were approached request participation. inclusion criteria participation age ≥18 years, ability understand, speak, read Italian, being at any gestational age. questionnaire, using combination checkboxes free text answers, consisted 32 items divided into five parts lasted ~10 min.The results showed that 61% recommended 48.7% could risky pregnancy; 74.1% wrongly reported Measles-Mumps-Rubella (MMR) pregnancy. Seven out 10 believed strong evidence supported safety vaccinations pregnancy, more than half (55.6%) thought they increased risk severe illness COVID-19. Women sample vaccines received pose adverse events unborn child median value 6 (IQR 3-9), scale ranging 1 10. Similarly, fear contracting 3-9) 5 3-8), respectively. Only 21.1% 36.5% Tdap pregnancy.Unrealistic perception negative attitude toward low percentage vaccinated confirm urgency training make informed choices increase overall uptake.

Language: Английский

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The determinants of COVID-19 vaccination intention: a meta-review

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: June 12, 2023

A large number of systematic reviews have been published that synthesized various determinants COVID-19 vaccination intention (CVI). However, they reported inconsistent evidence. Therefore, we conducted a meta-review (systematic review reviews) to provide comprehensive synthesis factors influencing CVI.

Language: Английский

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The Impact of Coronavirus Disease 2019 (COVID-19) on Vulnerable Communities

Infectious Disease Clinics of North America, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

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