Associations of personal care product use during pregnancy and the postpartum period with markers of postpartum glycemic control – Results from the ERGO Study DOI Creative Commons
Emma V. Preston,

Jennie Lytel-Sternberg,

Marlee R. Quinn

et al.

International Journal of Hygiene and Environmental Health, Journal Year: 2025, Volume and Issue: 266, P. 114569 - 114569

Published: March 31, 2025

Personal care products frequently contain endocrine disrupting chemicals (EDCs) including parabens and phthalates, which can alter glucose metabolism. The postpartum period is a time of rapid metabolic change, but whether EDC-associated product use impacts metabolism unknown. We included 270 participants from the Boston, MA-based Environmental Reproductive Glucose Outcomes (ERGO) pregnancy cohort with data on self-reported personal at ≤4 visits (median: 11, 19, 26, 36 weeks gestation) 1 visit 9 weeks). quantified hemoglobin A1c (HbA1c), fasting insulin, fasting- 2-h post-75-g oral tolerance test, calculated homeostatic model assessment for insulin sensitivity (HOMA2-S) beta-cell function (HOMA2-B). Using covariate-adjusted linear regression, we estimated visit-specific associations glycemic outcomes. Associations measures were mixed. Users certain hair had lower compared to non-users (e.g., Visit1 gel/spray: 22.8% difference [95% CI: 39.2, -1.9] in mean HOMA2-S). Conversely, users like deodorant, liquid- bar soap, higher levels deodorant: 32.1% 7.0, 63.1] HOMA2-S; -3.1 mg/dL 6.3, -0.04] glucose). other inconsistent across timepoints or null. Use during perinatal was associated altered Larger studies are needed understand patterns

Language: Английский

Associations of personal care product use during pregnancy and the postpartum period with markers of postpartum glycemic control – Results from the ERGO Study DOI Creative Commons
Emma V. Preston,

Jennie Lytel-Sternberg,

Marlee R. Quinn

et al.

International Journal of Hygiene and Environmental Health, Journal Year: 2025, Volume and Issue: 266, P. 114569 - 114569

Published: March 31, 2025

Personal care products frequently contain endocrine disrupting chemicals (EDCs) including parabens and phthalates, which can alter glucose metabolism. The postpartum period is a time of rapid metabolic change, but whether EDC-associated product use impacts metabolism unknown. We included 270 participants from the Boston, MA-based Environmental Reproductive Glucose Outcomes (ERGO) pregnancy cohort with data on self-reported personal at ≤4 visits (median: 11, 19, 26, 36 weeks gestation) 1 visit 9 weeks). quantified hemoglobin A1c (HbA1c), fasting insulin, fasting- 2-h post-75-g oral tolerance test, calculated homeostatic model assessment for insulin sensitivity (HOMA2-S) beta-cell function (HOMA2-B). Using covariate-adjusted linear regression, we estimated visit-specific associations glycemic outcomes. Associations measures were mixed. Users certain hair had lower compared to non-users (e.g., Visit1 gel/spray: 22.8% difference [95% CI: 39.2, -1.9] in mean HOMA2-S). Conversely, users like deodorant, liquid- bar soap, higher levels deodorant: 32.1% 7.0, 63.1] HOMA2-S; -3.1 mg/dL 6.3, -0.04] glucose). other inconsistent across timepoints or null. Use during perinatal was associated altered Larger studies are needed understand patterns

Language: Английский

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