Exercise for Postmenopausal Bone Health – Can We Raise the Bar? DOI Creative Commons
Shejil Kumar, Cassandra Smith, Roderick Clifton‐Bligh

et al.

Current Osteoporosis Reports, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 10, 2025

Abstract Purpose of Review This review summarises the latest evidence on effects exercise falls prevention, bone mineral density (BMD) and fragility fracture risk in postmenopausal women, explores hypotheses underpinning exercise-mediated BMD sheds light innovative concepts to better understand harness skeletal benefits exercise. Recent Findings Multimodal programs incorporating challenging balance exercises can prevent falls. Emerging clinical trial indicates supervised progressive high-intensity resistance impact training (HiRIT) is efficacious increasing lumbar spine safe well-tolerated women with osteoporosis/osteopenia. There remains uncertainty regarding durability this load-induced osteogenic response safety patients recent fractures. Muscle-derived myokines small circulating extracellular vesicles have emerged as potential sources exercise-induced muscle-bone crosstalk but require validation women. Summary Exercise has for multi-modal i) HiRIT build bone, ii) falls, ultimately The therapeutic effect such combination osteoporosis pharmacotherapy should be considered future trials.

Language: Английский

Exercise for Postmenopausal Bone Health – Can We Raise the Bar? DOI Creative Commons
Shejil Kumar, Cassandra Smith, Roderick Clifton‐Bligh

et al.

Current Osteoporosis Reports, Journal Year: 2025, Volume and Issue: 23(1)

Published: April 10, 2025

Abstract Purpose of Review This review summarises the latest evidence on effects exercise falls prevention, bone mineral density (BMD) and fragility fracture risk in postmenopausal women, explores hypotheses underpinning exercise-mediated BMD sheds light innovative concepts to better understand harness skeletal benefits exercise. Recent Findings Multimodal programs incorporating challenging balance exercises can prevent falls. Emerging clinical trial indicates supervised progressive high-intensity resistance impact training (HiRIT) is efficacious increasing lumbar spine safe well-tolerated women with osteoporosis/osteopenia. There remains uncertainty regarding durability this load-induced osteogenic response safety patients recent fractures. Muscle-derived myokines small circulating extracellular vesicles have emerged as potential sources exercise-induced muscle-bone crosstalk but require validation women. Summary Exercise has for multi-modal i) HiRIT build bone, ii) falls, ultimately The therapeutic effect such combination osteoporosis pharmacotherapy should be considered future trials.

Language: Английский

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