Comparison of COVID-19 and Influenza-Related Outcomes in the United States during Fall-Winter 2022-2023 DOI Open Access

Hagit Kopel,

Alina Bogdanov, Jessamine Winer‐Jones

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Sept. 11, 2023

Abstract Background Three years into the pandemic, SARS-COV-2 remains a significant burden in comparison to other respiratory illnesses; however, many of monitoring tools available during early phase COVID-19 pandemic have been phased out, making it more difficult track current outpatient medical encounters and hospitalizations, especially for at-risk groups. The objective this analysis was characterize frequency severity medically-attended influenza peak activity pediatric (0-17), adult (18-64), older (65+) populations prevalence underlying conditions among patients hospitalized with COVID-19. Methods This cross-sectional individuals Veradigm Health Insights EHR Database linked Komodo claims data encounter claim between October 1, 2022, March 31, 2023. We captured age, sex, associated higher risk severe 12-month baseline period. identified diagnosis or 2023, stratified them 5 mutually exclusive categories based on highest level care received that season (intensive unit [ICU] > hospitalization without ICU emergency department urgent outpatient). Results Among 23,526,196 dataset, 5.0% had COVID-19-related encounter, 3.0% an influenza-related 6 month observation incidence hospitalizations 4.6 times than diagnosis. Hospitalizations were all age Nearly adults at least one condition, but 25.8% 0-5-year-olds 18.3% 6-17-year-olds no conditions. Conclusions continues place heavy United States healthcare system groups, including 6-month period included 2022-2023 activity.

Language: Английский

Comparison of COVID-19 and Influenza-Related Outcomes in the United States during Fall–Winter 2022–2023: A Cross-Sectional Retrospective Study DOI Creative Commons

Hagit Kopel,

Alina Bogdanov, Jessamine Winer‐Jones

et al.

Diseases, Journal Year: 2024, Volume and Issue: 12(1), P. 16 - 16

Published: Jan. 3, 2024

Influenza and COVID-19 contribute significantly to the infectious disease burden during respiratory season, but their relative remains unknown. This study characterizes frequency severity of medically attended influenza peak 2022–2023 season in pediatric, adult, older adult populations prevalence underlying conditions among patients hospitalized with COVID-19. cross-sectional analysis included individuals Veradigm EHR Database linked Komodo claims data a medical encounter between 1 October 2022 31 March 2023 (study period). Patients encounters were identified diagnosis or period stratified based on highest level care received that diagnosis. Among 23,526,196 individuals, there more COVID-19-related than influenza-related encounters, overall by outcome. Hospitalizations common hospitalizations (incidence ratio = 4.6) all age groups. Nearly adults had at least one condition, 37.1% 0–5-year-olds 25.0% 6–17-year-olds no conditions. was associated greater season.

Language: Английский

Citations

13
Differences in clinical characteristics between coronavirus disease 2019 (COVID-19) and influenza: a systematic review and meta-analysis DOI Creative Commons
Yingying Han, Jia Guo, Xingzhao Li

et al.

npj Primary Care Respiratory Medicine, Journal Year: 2025, Volume and Issue: 35(1)

Published: Jan. 28, 2025

The coronavirus disease 2019 (COVID-19) epidemic has brought major challenges to the global health system, and influenza is also a problem that cannot be ignored. We aimed explore compare clinical characteristics of COVID-19 deepen understanding these two diseases provide some guidance for clinicians make differential diagnoses. searched PubMed, Embase Web Science articles performed meta-analysis using Stata 14.0 with random-effects model. This was conducted in accordance Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) guidelines. One hundred involving 226,913 patients 201,617 were included, all included as experimental control groups. Compared influenza, more common among men (OR = 1.46, 95% CI: 1.23–1.74) people higher body mass index (MD 1.43, 1.09–1.77). proportion current smokers lower than 0.25, 0.18–0.33). Patients had longer stays hospital 3.20, 2.58–3.82) ICU 3.10, 1.44–4.76), required mechanical ventilation frequently 2.30, 1.77–3.00), mortality 2.22, 1.93–2.55). found significant differences blood parameters between groups patients. Upper respiratory symptoms obvious patients, comorbidities There are characteristics, symptoms, laboratory findings often require medical resources have worse outcomes.

Language: Английский

Citations

1
Changes in emergency department use in British Columbia, Canada, during the first 3 years of the COVID-19 pandemic DOI Creative Commons
Jiayun Yao, Michael A. Irvine,

Braeden Klaver

et al.

Canadian Medical Association Journal, Journal Year: 2023, Volume and Issue: 195(34), P. E1141 - E1150

Published: Sept. 4, 2023

Previous studies have shown reductions in the volume of emergency department visits early COVID-19 pandemic, but few evaluated pandemic's impact over time or stratified analyses by reason for visits. We aimed to quantify such changes British Columbia, Canada, cumulatively and during prominent nadirs, visit, age acuity.We included data from National Ambulatory Care Reporting System 30 departments across BC January 2016 December 2022. fitted generalized additive models, accounting seasonal annual trends, monthly number estimate throughout compared with expected absence pandemic. determined absolute relative differences at various times study period, since start pandemic until overall returned levels.Over first 16 months was reduced about 322 300 visits, 15% (95% confidence interval 12%-18%), volume. A sharp drop pediatric accounted nearly one-third reduction. The timing return baseline differed subgroup. largest most sustained decreases were respiratory-related among children, oldest adults non-urgent Later we observed increased volumes highest-urgency children related ear, nose throat.We extended evidence that associated mitigation strategies on Canada substantial. Both our findings methods are relevant public health surveillance capacity planning nonpandemic times.

Language: Английский

Citations

16
Cohort profile: the British Columbia COVID-19 Cohort (BCC19C)—a dynamic, linked population-based cohort DOI Creative Commons
James Wilton,

Jalud Abdulmenan,

Mei Sian Chong

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Feb. 21, 2024

The British Columbia COVID-19 Cohort (BCC19C) was developed from an innovative, dynamic surveillance platform and is accessed/analyzed through a cloud-based environment. integrates recently provincial datasets (refreshed daily) with existing administrative holdings registries weekly/monthly). platform/cohort were established to inform the response in near "real-time" answer more in-depth epidemiologic questions.

Language: Английский

Citations

6
Longitudinal wastewater surveillance of four key pathogens during an unprecedented large-scale COVID-19 outbreak in China facilitated a novel strategy for addressing public health priorities–A proof of concept study DOI
Songzhe Fu, Yixiang Zhang, Rui Wang

et al.

Water Research, Journal Year: 2023, Volume and Issue: 247, P. 120751 - 120751

Published: Oct. 19, 2023

Language: Английский

Citations

8
Outcomes of Pediatric SARS-CoV-2 Omicron Infection vs Influenza and Respiratory Syncytial Virus Infections DOI Creative Commons
Pontus Hedberg, Lina Abdel-Halim, John Karlsson Valik

et al.

JAMA Pediatrics, Journal Year: 2023, Volume and Issue: 178(2), P. 197 - 197

Published: Dec. 26, 2023

This cohort study compares outcomes of SARS-CoV-2 Omicron infection with those influenza or respiratory syncytial virus in pediatric patients attending the emergency department.

Language: Английский

Citations

7
Risk of hospital admission and death from first-ever SARS-CoV-2 infection by age group during the Delta and Omicron periods in British Columbia, Canada DOI Creative Commons
Danuta M. Skowronski,

Samantha E Kaweski,

Michael A. Irvine

et al.

Canadian Medical Association Journal, Journal Year: 2023, Volume and Issue: 195(42), P. E1427 - E1439

Published: Oct. 29, 2023

Population-based cross-sectional serosurveys within the Lower Mainland, British Columbia, Canada, showed about 10%, 40% and 60% of residents were infected with SARS-CoV-2 by sixth (September 2021), seventh (March 2022) eighth (July serosurveys. We conducted ninth (December tenth 2023) sought to assess risk severe outcomes from a first-ever infection during intersurvey periods.Using increments in cumulative infection-induced seroprevalence, population census, discharge abstract vital statistics data sets, we estimated hospitalization fatality ratios (IHRs IFRs) age sex for (Delta/Omicron-BA.1), (Omicron-BA.2/BA.5) (Omicron-BA.5/BQ.1) periods. As derived, IHR IFR estimates represent outcome acquired specified period.The seroprevalence was 74% December 2022 79% July 2023, exceeding 80% among adults younger than 50 years but remaining less those aged 80 older. Period-specific consistently 0.3% 0.1% overall. By group, 1.0% up 0.1%, respectively, except 70-79 period (IHR 3.3% 1.0%) older all periods 4.7%, 2.2% 3.5%; 3.3%, 0.6% 1.3% seventh, periods, respectively). The followed J-shaped pattern. During period, 1 hospital admission COVID-19 per 300 newly children 5 versus 30 older, no deaths death that period.By BC, had been overall, low or death; oldest adults, however, remained uninfected at highest outcome. First infections may still contribute substantial burden COVID-19, reinforcing need continue prioritize this group vaccination consider them health care system planning.

Language: Английский

Citations

6
Is COVID-19 finally just a bad flu? Follow-up study comparing disease severity among COVID-19 and seasonal influenza hospital in-patients across pandemic waves in Ireland DOI
A O’Farrell, P Naughton, Paul Kavanagh

et al.

Public Health, Journal Year: 2024, Volume and Issue: 236, P. 15 - 20

Published: Aug. 17, 2024

Language: Английский

Citations

1
Neonatal COVID-19 treatment: Are there new chances? DOI

Mohamed Shawky Elfarargy,

Thamer Alshami Marghel Alruwaili,

AbdulRahim Ahmad

et al.

Journal of Neonatal-Perinatal Medicine, Journal Year: 2024, Volume and Issue: 17(4), P. 501 - 507

Published: May 14, 2024

Coronavirus disease 2019 (COVID-19) is considered an infectious which caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Neonatal COVID-19 had been occurred in many countries would indicate the need of effective and safe treatment for these vulnerable group. In this study, we showed symptoms corona virus neonates, investigation neonates radiological features neonatal COVID-19. addition, discussed management COVI-19, antiviral treatment, monoclonal antibodies administration, immunomodulatory therapy, antibiotics, vitamins, minerals COVID-19, also telemedicine feeding newborn mother. We multisystem inflammatory (MIS-N), affected discussion complication further methods dealing research done on treatment.

Language: Английский

Citations

0
Short- and Long-term Outcomes of children hospitalized with COVID-19 or Influenza: results of the AUTCOV study DOI Creative Commons

Christine Wagenlechner,

Ralph Wendt, Berthold Reichardt

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 28, 2024

Abstract Background Recent literature gives different results on morbidity and mortality after COVID-19 as compared to Influenza hospitalized children of large, population based studies are scant. In this population-based study in Austria, we evaluated the short- long-term outcomes or hospitalization associations with their baseline drug profile. Methods Individual data were provided ≤ 18 years 2020 2021 2016 – well age-, sex- region-matched controls from Austrian Health Insurance Funds. The primary outcome was time hospital discharge. Secondary in-hospital death, all-cause readmission due any reason. median follow-up 430 days (IQR: 245-552) 1221 881-1599) group. Results 1063 2781 period. Children more likely have a larger disease burden general population. patients observed be generally younger percentage polypharmacy than those COVID-19. No significant difference discharge found between cohorts (HR: 1.22 [95%-CI: 0.97-1.55], p=0.093). risk for significantly higher 1.23 1.03-1.47], p=0.021). In-hospital (0.94% vs. 0.22%, p=0.004) (p=0.009) patients. One-year estimated 1.13% (CI: 0.49-1.77) COVID 0.32% 0.11-0.53) Conclusion A picture being milder may not drawn. but Death rates seem higher, however, low number severe events limit findings.

Language: Английский

Citations

0