Alterations in menstrual characteristics and associated factors in Chinese women post SARS-CoV-2 infection: a cross-sectional study

BMC Women s Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 18, 2025

Following a significant relaxation of restrictions in China on December 7, 2022, after surge SARS-CoV-2 infections, an uptick women presenting with menstrual disorders was observed clinics. This study aimed to explore the alterations characteristics and associated factors post infection. A cross-sectional online survey conducted among 869 non-amenorrheic adult Chinese females (aged 18–53) changes other infection-related initial The reported (group A) were compared no B). Data collected included basic individual-level information such as age, height, weight, history, reproductive disorders, chronic diseases, vaccination status, COVID-19 symptoms, (regularity, period volume, degree dysmenorrhea) Of participants, 442 (50.9%, group at least one characteristic; 171 (19.7%) experienced extended cycle, 122 (14.0%) decrease volume. Participants who more likely have pre-existing diseases (7.7% vs. 3.0%, P = 0.003) exhibit symptoms during acute (4.94 4.03, < 0.001) recovery (4.37 3.41, phases. These participants also report fever symptom (93.4% 86.9%, longer duration (2.25 1.96 days, B. Notably, fewer vaccine doses, COVID-19-related frequent (P 0.05) than may experience infection according self-report results this study.

Language: Английский

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Evaluating the impact of menstrual/menopausal symptoms on mental health among female workers during the pandemic

European Journal of Obstetrics & Gynecology and Reproductive Biology, Journal Year: 2025, Volume and Issue: unknown, P. 113938 - 113938

Published: March 1, 2025

Language: Английский

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Response to Letter to the Editor concerning “Evaluating the impact of menstrual/menopausal symptoms on mental health among female workers during the pandemic” by K. Hirokawa et al

European Journal of Obstetrics & Gynecology and Reproductive Biology, Journal Year: 2025, Volume and Issue: unknown, P. 113962 - 113962

Published: April 1, 2025

Language: Английский

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Menstrual Cycle Length Changes Following Vaccination Against Influenza Alone or With COVID-19

JAMA Network Open, Journal Year: 2025, Volume and Issue: 8(4), P. e257871 - e257871

Published: April 29, 2025

Importance Multiple studies have identified an association between COVID-19 vaccination and menstrual disturbances. Data on whether health is impacted by other vaccines are needed to counsel individuals about what expect address vaccine hesitancy. Objective To assess the of changes in length cycle with influenza vaccination, or without concurrent receipt a vaccine. Design, Setting, Participants This global retrospective cohort study prospectively collected data from April 25, 2023, February 27, 2024 (4-5 cycles per individual), among international English-speaking users digital birth control application. included aged 18 45 years, not using hormonal contraception, average lengths 24 38 days 3 consecutive before vaccines. Exposure Seasonal Main Outcome Measure The primary outcome consisted adjusted mean within-individual assessed group. Secondary analysis evaluated phase at time vaccination. Results A total 1501 met inclusion criteria, whom 791 were vaccinated for only 710 concurrently COVID-19. By race ethnicity, 1 participant (0.1%) was American Indian Alaska Native; 10 (0.7%), Asian; (0.2%), Black; 15 (1.0%), Hispanic Latina; (0.1%), Middle Eastern North African; 368 (24.5%), White; 19 (1.3%), other; 1084 (72.2%), missing. Most younger than 35 years (1230 [82.0%]), had least college degree (1122 [74.8%]), located US Canada (938 [62.5%]). Individuals alone experienced increase 0.40 (95% CI, 0.08-0.72) days, while those 0.49 0.16-0.83) ( P = .69 difference groups). 37 (4.7%) change 8 42 (5.9%) both .28). In postvaccination cycle, groups returned their prevaccination lengths. Menstrual occurred follicular but luteal phase. Conclusions Relevance this regular cycles, given combination associated small temporary length. These findings may help clinicians confirm utility patients concerns adverse effects

Language: Английский

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COVID-19 Modified mRNA “Vaccines”: Lessons Learned from Clinical Trials, Mass Vaccination, and the Bio-Pharmaceutical Complex, Part 2

International Journal of Vaccine Theory Practice and Research, Journal Year: 2024, Volume and Issue: 3(2), P. 1275 - 1344

Published: Aug. 16, 2024

The COVID-19 modified mRNA (modmRNA) lipid nanoparticle-based “vaccines” are not classical antigen-based vaccines but instead prodrugs informed by gene therapy technology. Of considerable note, these products have been linked to atypical adverse and serious event profiles. As discussed in Part 1, health-related risks drawbacks were drastically misreported underreported the Pfizer Moderna trial evaluations of genetic products. Now 2, we examine main structural functional aspects injectables. modmRNA injectable introduce a unique set biological challenges human body with potential induce an extensive range adverse, crippling, life-threatening effects. Based on fact that there is no current method quantify host (cell-based) spike protein production vivo following injection prodrugs, standard “dose”. This part due differences output, which depends cell metabolism transfection efficiency. It therefore difficult predict profiles individual basis, considering millions adults across world reported severe events context products, valid concerns raised regarding infants younger age groups for whom poses only minimal risks. We address process-related impurities inherent mass posed contaminants. then categorize principal associated brief systems-based synopsis each six domains harms: (1) cardiovascular, (2) neurological, (3) hematologic; (4) immunological, (5) oncological, (6) reproductive. conclude discussion primary public health regulatory issues arising from this evidence-informed synthesis literature reiterate urgency imposing global moratorium modmRNA-LNP-based platform.

Language: Английский

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Covid-19 vaccination and menstrual bleeding disturbances among women of fertile age: a Norwegian registry study

European Journal of Epidemiology, Journal Year: 2024, Volume and Issue: 39(10), P. 1127 - 1138

Published: Oct. 1, 2024

Abstract This study evaluated the relationship between Covid-19 vaccination and menstrual bleeding disturbances using a large national registry linkage including 666,467 women 20 40 years of age residing in Norway on January 1st, 2019. Information vaccination—BNT162b2 mRNA-1273 — was obtained from Norwegian registry. Diagnoses (absent/scanty, excessive, irregular/frequent menstruation, intermenstrual bleeding) general practitioner database. We examined new-onset Cox regression comparing vaccinated to unvaccinated women, where contributed follow-up time as until day vaccination. In addition, we conducted self-controlled case-series analysis, sensitivity analysis excluding all those who remained throughout pandemic, evaluate role unmeasured confounding. observed an increased risk several after against Covid-19, ranging adjusted HR (aHR) 1.18 (95% CI: 1.04, 1.33) for 1.29 1.23, 1.36) periods. However, estimates were fully attenuated when at end (aHRs 0.97 1.08). No differences identified according vaccine dose or type. Our case series confirmed no first vaccination, though there slightly 61 days with 2. conclusion, modestly appeared reflect confounding by never received vaccinations, associations did not remain compared before among ever women.

Language: Английский

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Prevalence of menstrual alterations following COVID-19 vaccination: systematic review & meta-analysis

BMC Women s Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 19, 2024

Language: Английский

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Relation Between COVID-19 Infection and Vaccine and Menstrual Cycle Changes of Portuguese Adolescents in Higher Education

Healthcare, Journal Year: 2024, Volume and Issue: 13(1), P. 2 - 2

Published: Dec. 24, 2024

In a period globally known as long COVID, several post-acute infection sequelae and vaccination effects have been discussed. Objectives: This study aimed to identify the of COVID-19 vaccines on menstrual cycle adolescents attending higher education verify association between personal health factors changes in their after contact with virus SARS-CoV-2 via or vaccine. Methods: A cross-sectional was conducted using questionnaire for data collection, applied online Portuguese aged 18 24. The sample included 401 individuals. statistical analysis performed SPSS. Results: More than half had only once took two doses mRNA Comirnaty 30 µg BioNTech vaccine administered 73.1%. most common were an increase blood clots, becoming darker, shorter cycles, scarcer flow, more irregular cycles. Menstrual correlated significantly but not infection. Conclusions: showed lower percentage women affected other studies carried out closer pandemic period, which could mean that are diminishing over time. Thus, adolescents’ should be monitored.

Language: Английский

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Association between menstrual cycle pattern regularity and changes in menstrual bleeding following COVID-19 vaccination: secondary analysis of an observational study

BMJ Sexual & Reproductive Health, Journal Year: 2024, Volume and Issue: unknown, P. bmjsrh - 202564

Published: Dec. 31, 2024

Language: Английский

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