Frontiers in Psychiatry,
Journal Year:
2020,
Volume and Issue:
11
Published: Dec. 21, 2020
Recent
reports
suggest
that
the
COVID-19
lockdown
resulted
in
changes
mental
health,
however,
potential
age-related
and
risk
factors
remain
unknown.
We
measured
lockdown-induced
stress
levels
severity
of
depressive
symptoms
prior
to
during
different
age
groups
then
searched
for
a
well-characterized
general
population-based
sample.
A
total
715
participants
were
tested
distress
related
at
two
time-points,
baseline
testing
follow-up
COVID-19,
using
battery
validated
psychological
tests
including
Perceived
Stress
Scale
Patient
Health
Questionnaire.
Longitudinal
measurements
revealed
prevalence
moderate
high
increased
1.4-
5.5-fold,
respectively,
lockdown.
This
surge
was
more
severe
women,
but
present
all
with
older
group
exhibiting,
cross-sectionally,
lowest
Illness
perception,
personality
characteristics
such
as
feeling
loneliness,
several
lifestyle
components
found
be
associated
significant
increase
distress.
The
observed
health
identified
underlying
these
provide
critical
data
justifying
timely
public
emergency-tailored
preventive,
diagnostic,
therapeutic
interventions,
which
should
integrated
into
future
policies
globally.
COVID-19
has
infected
millions
of
people
and
upended
the
lives
most
humans
on
planet.
Researchers
from
across
psychological
sciences
have
sought
to
document
investigate
impact
in
myriad
ways,
causing
an
explosion
research
that
is
broad
scope,
varied
methods,
challenging
consolidate.
Because
policy
practice
aimed
at
helping
live
healthier
happier
requires
insight
robust
patterns
evidence,
this
paper
provides
a
rapid
thorough
summary
high-quality
studies
available
through
early
2021
examining
mental
health
consequences
living
pandemic.
Our
review
evidence
indicates
anxiety,
depression,
distress
increased
months
Meanwhile,
suicide
rates,
life
satisfaction,
loneliness
remained
largely
stable
throughout
first
year
In
response
these
insights,
we
present
seven
recommendations
(one
urgent,
two
short-term,
four
ongoing)
support
during
pandemic
beyond.
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2020,
Volume and Issue:
unknown
Published: June 4, 2020
Abstract
Background
There
is
currently
major
concern
about
the
impact
of
global
COVID-19
outbreak
on
mental
health.
A
number
studies
suggest
that
health
deteriorated
in
many
countries
prior
to
and
during
enforced
isolation
(“lockdown”),
but
it
remains
unknown
how
has
changed
week
by
over
course
pandemic.
Aims
This
study
explored
trajectories
anxiety
depression
20
weeks
after
lockdown
was
announced
using
data
from
England,
compared
growth
individual
characteristics.
Methods
Data
36,520
adults
UCL
COVID
-19
Social
Study
(a
well-stratified
panel
weighted
population
proportions
collecting
weekly
pandemic)
were
analysed
23/03/2020-09/08/2020.
Latent
models
fitted
accounting
for
socio-demographic
covariates.
Results
22.6%
sample
had
scores
indicating
moderate-severe
anxiety,
25.1%
depressive
symptoms.
Anxiety
levels
both
declined
across
first
following
introduction
England.
The
fastest
decreases
seen
strict
period,
with
symptoms
plateauing
as
further
easing
measures
introduced.
Being
female
or
younger,
having
lower
educational
attainment,
income
pre-existing
conditions,
living
alone
children
all
risk
factors
higher
at
start
lockdown.
Many
these
inequalities
experiences
reduced
continued,
differences
still
evident
Conclusions
As
face
potential
future
lockdowns,
highest
are
early
stages
decline
fairly
rapidly
individuals
adapt
circumstances.
They
also
importance
supporting
lead-up
being
brought
try
reduce
distress
highlight
emotionally
vulnerable
groups
have
remained
throughout
its
aftermath.
Research
context
Evidence
before
this
representative
cohort
highlighted
substantial
pandemic
depression,
distress,
showing
increases
average
psychological
well
a
rise
proportion
people
experiencing
clinically
significant
illness.
But
Added
value
finds
Specific
poorer
identified.
Implications
available
evidence:
globally
look
longitudinally
Overall,
findings
England
known
apparent
lockdown,
some
experienced
faster
improvements
symptoms,
thereby
reducing
time.
Nevertheless,
did
remain
implications
planning
support
waves
virus.
BMC Geriatrics,
Journal Year:
2021,
Volume and Issue:
21(1)
Published: July 26, 2021
The
objective
of
this
study
was
to
examine
factors
that
threatened
and
protected
the
wellbeing
older
adults
living
in
UK
during
social
distancing
restrictions
due
COVID-19
pandemic.Semi-structured
telephone
or
video
interviews
with
20
aged
over
70.
Purposive
sampling
methods
were
used
increase
diversity
within
group.
Transcripts
analysed
using
reflexive
thematic
analysis.Participants
described
potential
threats
their
pandemic,
including
fears
for
mortality,
grieving
normal
life,
concerns
future.
Participants
also
activities
behaviours
helped
protect
mental
health,
adopting
a
slower
pace
maintaining
routine,
socialising,
past
coping
skills.
Many
participants
drew
on
resilience
life
experience
self-manage
fear
uncertainty
associated
time
lockdown
reflect
organise
end-of-life
affairs.This
provides
UK-based
evidence
while
some
experienced
challenges
first
wave
COVID-19,
many
resilient
throughout
despite
early
reported
health
consequences
among
adult
population.
Our
findings
highlight
importance
access
essentials
promote
feelings
normality
use
support
help
reduce
times
pandemics.
BMC Psychology,
Journal Year:
2021,
Volume and Issue:
9(1)
Published: July 15, 2021
Abstract
Background
Individuals
face
increased
psychological
distress
during
the
COVID-19
pandemic.
However,
it’s
unknown
whether
choice
of
coping
styles
are
influenced
by
in
addition
to
known
predictors.
Methods
Data
from
26,016
UK
adults
UCL
Social
Study
were
analysed
12/4/2020
15/5/2020.
Regression
models
used
identify
predictors
(problem-focused,
emotion-focused,
avoidant,
and
socially-supported):
model
1
included
sociodemographic
variables,
2
additionally
psychosocial
factors,
3
further
experience
specific
adverse
worries
or
events.
Results
Sociodemographic
align
with
usual
not
occurring
a
even
when
controlling
for
wide
range
these
previously
adversities
associated
use
strategies.
Experience
about
finances,
basic
needs,
events
related
Covid-19
strategies,
while
financial
was
problem-focused,
emotion-focused
avoidant
coping.
There
no
associations
between
experiencing
challenges
meeting
but
lower
socially-supported
Conclusions
This
paper
demonstrates
that
there
only
demographic
social
pandemic,
ways
cope.
Furthermore,
this
study
identifies
groups
at
risk
more
mechanisms
which
may
be
targeted
supportive
interventions.
SSRN Electronic Journal,
Journal Year:
2020,
Volume and Issue:
unknown
Published: Jan. 1, 2020
Background:
Lockdowns
reduce
the
spread
of
COVID-19
but
there
are
concerns
about
their
effect
upon
mental
health.
We
assess
this
by
examining
subjective
well-being
during
lockdown,
carefully
distinguishing
lockdowns
from
that
pandemic
using
weekly
data.
Methods:
use
data
YouGov's
Great
Britain
Mood
Tracker
Poll
and
reports
Google
Trends.
The
YouGov
comprises
a
weekly,
repeated
cross
sectional
survey
1,890-2,071
respondents
in
Britain,
representative
age,
gender,
social
class,
education.
It
employs
Profile
State
(POMS)
battery
Cantril's
ladder
life
satisfaction
scale
to
respondent's
well-being.
Trends
enables
relative
popularity
search
terms
be
analysed.
validate
'negative
affect
index'
we
employ
whether
other
English-speaking
countries
experienced
similar
trends
Britain.
Time
series
models
were
estimated
gauge
on
Findings:
Our
modelling
suggests
one-month
period
lockdown
reduces
negative
around
-9%
pre-pandemic
baseline,
rising
-17%
when
sample
space
is
restricted
following
onset.
results
support
hypothesis
country-specific
severity,
not
was
major
contributor
increases
observed
studies
Interpretation:
response
outbreaks
improve
overall.Funding
Statement:
No
funding
provided
for
production
research.Declaration
Interests:
authors
declare
they
have
no
conflict
interest(s).
PLoS ONE,
Journal Year:
2021,
Volume and Issue:
16(1), P. e0244873 - e0244873
Published: Jan. 5, 2021
Background
Multiple
studies
have
highlighted
the
negative
impact
of
COVID-19
and
its
particular
effects
on
vulnerable
sub-populations.
Complementing
this
work,
here,
we
report
social
patterning
self-reported
positive
changes
experienced
during
national
lockdown
in
Scotland.
Methods
The
CATALYST
study
collected
data
from
3342
adults
Scotland
weeks
9–12
a
lockdown.
Using
cross-sectional
design,
participants
completed
an
online
questionnaire
providing
key
sociodemographic
health
variables,
measure
change.
change
spanned
diverse
domains
(e.g.,
more
quality
time
with
family,
developing
new
hobbies,
physical
activity,
better
sleep).
We
used
univariate
analysis
stepwise
regression
to
examine
contribution
range
factors
age,
gender,
ethnicity,
educational
attainment,
employment
status)
explaining
Results
There
were
clear
differences
across
scores.
Those
reporting
higher
levels
female,
younger
age
groups,
married
or
living
their
partner,
employed,
health.
Conclusion
Overall
our
results
highlight
These
findings
begin
illuminate
complexity
unanticipated
will
be
support
future
intervention
development
work
sharing
lessons
learned
increase
amongst
those
who
may
benefit.
The EMBO Journal,
Journal Year:
2021,
Volume and Issue:
40(20)
Published: Sept. 12, 2021
The
current
pandemic
caused
by
severe
acute
respiratory
syndrome
coronavirus
2
(SARS-CoV-2)
and
outbreaks
of
new
variants
highlight
the
need
for
preventive
treatments.
Here,
we
identified
heparan
sulfate
proteoglycans
as
attachment
receptors
SARS-CoV-2.
Notably,
neutralizing
antibodies
against
SARS-CoV-2
isolated
from
COVID-19
patients
interfered
with
binding
to
proteoglycans,
which
might
be
an
additional
mechanism
neutralize
infection.
infection
epithelial
cells
was
blocked
low
molecular
weight
heparins
(LMWH).
Although
dendritic
(DCs)
mucosal
Langerhans
(LCs)
were
not
infected
SARS-CoV-2,
both
DC
subsets
efficiently
captured
via
transmitted
virus
ACE2-positive
cells.
human
primary
nasal
pre-treatment
LMWH.
These
data
strongly
suggest
that
are
important
facilitating
transmission,
support
use
LMWH
prophylaxis
BMC Public Health,
Journal Year:
2021,
Volume and Issue:
21(1)
Published: April 12, 2021
Abstract
Background
Significant
differences
in
COVID-19
incidence
by
gender,
class
and
race/ethnicity
are
recorded
many
countries
the
world.
Lockdown
measures,
shown
to
be
effective
reducing
number
of
new
cases,
may
not
have
been
same
way
for
all,
failing
protect
most
vulnerable
populations.
This
survey
aims
assess
social
inequalities
trends
infections
following
lockdown.
Methods
A
cross-sectional
conducted
among
general
population
France
April
2020,
during
Ten
thousand
one
hundred
participants
aged
18–64,
from
a
national
cohort
who
lived
three
metropolitan
French
regions
affected
first
wave
COVID-19.
The
main
outcome
was
occurrence
possible
symptoms,
defined
as
sudden
onset
cough,
fever,
dyspnea,
ageusia
and/or
anosmia,
that
lasted
more
than
3
days
15
before
survey.
We
used
multinomial
regression
models
identify
health
factors
related
Results
In
1304
(13.0%;
95%
CI:
12.0–14.0%)
reported
cases
effect
lockdown
on
different
across
hierarchies.
privileged
individuals
saw
significant
decline
between
period
prior
(from
8.8
4.3%,
P
=
0.0001)
while
less
pronounced
working
(6.9%
5.5%
lockdown,
0.03).
differential
remained
after
adjusting
other
including
history
chronic
disease.
odds
being
infected
opposed
increased
57%
(OR
1.57;
1.00–2.48).
true
those
engaged
in-person
professional
activities
1.53;
1.03–2.29).
Conclusions
associated
with
infections,
calling
adoption
preventive
policies
account
living
conditions.
Such
adoptions
critical
reduce
COVID-19,
working-class
also
highest
mortality,
due
higher
prevalence
comorbidities.
Population Health Management,
Journal Year:
2021,
Volume and Issue:
25(3), P. 384 - 391
Published: Oct. 15, 2021
The
COVID-19
pandemic
has
caused
disproportionate
suffering
among
vulnerable
and
socioeconomically
disadvantaged
portions
of
the
population.
Low-income
minority
populations
are
likely
to
experience
disparate
disease
mental
health
burdens.
Currently,
there
is
little
evidence
regarding
how
early
months
US
outbreak
differed
by
income
level,
that
related
symptoms.
present
study
used
data
from
a
national
sample
adults
(n
=
5023)
who
completed
measures
COVID
experience,
Fear
Scale,
Generalized
Anxiety
Disorder-7
(GAD-7),
Patient
Health
Questionnaire-8
(PHQ-8).
Multivariable
regression
was
performed
determine
whether
level
(low:
<$45,000
vs
high:
≥$75,000)
significantly
associated
with
measures,
PHQ-8,
GAD-7,
fear
scores.
Among
low-income
group,
had
greater
negative
impact
on:
family
income/employment,
access
food,
treatment,
stress
discord
in
family.
Participants
group
also
odds
PHQ-8
score
≥10
(odds
ratio
[OR]
1.38,
95%
confidence
interval
[CI]
1.08,
1.77)
GAD-7
(OR
1.65,
CI
1.27,
2.14)
compared
those
high-income
group.
Study
findings
suggest
substantial
differences
impacted
daily
life
between
living
households
high-earning
during
pandemic.