Efficacy of Oriental Exercises for Non-Motor Symptoms and Quality of Life in Parkinson’s Disease: A Systematic Review and Meta-Analysis DOI Creative Commons
Wanqing Peng, Renhui Zhao, Zhong-qin Huang

et al.

The American Journal of Chinese Medicine, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 24, 2024

Parkinson’s disease (PD) is a progressive neurodegenerative disorder without definitive cure. Oriental exercises (OEs) have emerged as complementary and alternative therapy for PD, but their efficacy in ameliorating non-motor symptoms (NMS) quality of life (QOL) remains uncertain. This systematic review meta-analysis actively investigated the OEs addressing NMS enhancing QOL sought to offer recommendations optimal OE regimens PD patients. By analyzing 30 controlled trials involving 2029 participants, we found that significantly improved cognitive function, neuropsychiatric symptoms, compared control groups. Specifically, significant improvements were observed several outcome measures: Disease Questionnaire (PDQ) [MD: [Formula: see text]3.67, 95% CI: text]5.72–[Formula: text]1.63, text], text]%], Non-Motor Symptom (NMSQ) text]2.34, text]4.67–[Formula: text]0.01, Montreal Cognitive Assessment (MoCA) 1.75, 1.46–2.03, Stroop Color Word Test (SCWT) 0.87, 0.49–1.24, Frontal Battery (FAB) 1.49, 1.16–1.81, Hamilton Depression Scale (HAMD) text]4.27, text]6.85–[Formula: text]1.69, Anxiety (HAMA) text]0.24, text]0.32–[Formula: text]0.16, Checklist-90 (SCL-90) text]0.37, text]0.48–[Formula: text]0.25, text]%]. Our findings provide compelling evidence potential benefits managing improving To optimize outcomes, recommend customizing based on individual clinical phenotypes, validate these results emphasize need rigorous, large-scale studies.

Language: Английский

Identification of Cognitive Training for Individuals with Parkinson’s Disease: A Systematic Review DOI Creative Commons
Marina Francesca Gattoni, Silvia Gobbo, Sarah Feroldi

et al.

Brain Sciences, Journal Year: 2025, Volume and Issue: 15(1), P. 61 - 61

Published: Jan. 11, 2025

Background/Objectives: Parkinson’s disease (PD) is a neurodegenerative disorder, characterised by cardinal motor features and multitude of non-motor manifestations. Among them, cognitive impairment in PD has been recognised as defined clinical entity, it might lead to an increased risk developing dementia. Consequently, the present review aimed ascertain available interventions for training abilities persons with (PwPD). Methods: PRISMA guidelines were followed select studies following databases: PubMed, PsycINFO, Web Science. Two independent reviewers conducted different phases review, third expert was called address any doubts/conflicts. Randomised controlled trials randomised concerning outcomes PwPD selected. Results: A total 28 articles included. The considered applied various experimental functions PwPD: computer-based platforms, exergames, paper-and-pencil programmes, dual-task or treadmill action observation therapy, imagery, virtual reality components, targeting precise domain, tele-rehabilitation, transcranial direct current stimulation, structured training, multimodal treatments. Cognitive assessed employing neuropsychological tests, self-report questionnaires, computerised batteries. Conclusions: Overall, reported better performances groups compared control groups, several domains. Structured emerged most effective strategy enhance functioning PwPD. However, further are necessary determine appropriate useful develop that also consider patients’ quality life.

Language: Английский

Citations

0
An eco-friendly, sodium alginate degradable conformal triboelectric nanogenerator for self-powered sensing and real-time injury monitoring DOI
Qingyang Feng,

Zhenning Xie,

Yuzhang Wen

et al.

Sustainable materials and technologies, Journal Year: 2025, Volume and Issue: unknown, P. e01262 - e01262

Published: Jan. 1, 2025

Language: Английский

Citations

0
Global trends and interdisciplinary insights in Tai Chi research: a bibliometric analysis (2004–2024) DOI Creative Commons
B. Li, Xiwei Zhu, Hao‐Li Zhang

et al.

Frontiers in Medicine, Journal Year: 2025, Volume and Issue: 12

Published: April 10, 2025

Tai Chi, as a traditional Chinese martial art, has received extensive attention in recent years due to its multiple health benefits. Research demonstrates that Chi improves physical health, enhances flexibility and coordination, alleviates psychological stress. With the increase research, benefits of have been confirmed by many scientific studies. Therefore, bibliometric analysis literature can help us better understand research status development trends this field. The article commentary on from 2004 2024 were retrieved Web Science Core Collection. We used bibliometric.com online platform VOSviewer software analyze collaboration between countries/institutions/journals/authors, well co-occurrence keywords hotspots. Disciplinary distribution was analyzed using subject categories, visualized through VOSviewer's clustering algorithm. From 2023, number papers related showed an overall upward trend, with 12.3% average annual growth rate post-2012. China contributed 68.5% publications (n = 645/941), followed United States (15.2%, n 143). Key findings include 40% reduction fall risk (RR 0.60, 95% CI: 0.52-0.69) 33% improvement sleep quality (p < 0.001) among elderly practitioners. author network map shows authors like Wayne, Peter M. significant influence field research. Keyword reveals several main themes research: benefits, disease management, social regional cultural factors. is growing globally, potential are increasingly recognized. leads other countries regions. interdisciplinary, involving academic fields. value improving elderly, preventing falls, enhancing cognitive function, managing chronic diseases. Future further explore long-term effects, mechanisms action, application different populations.

Language: Английский

Citations

0
Identification of Parkinson's disease subtypes with distinct brain atrophy progression and its association with clinical progression DOI Creative Commons

Guoqing Pan,

Yuchao Jiang, Wei Zhang

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 4

Published: Jan. 1, 2024

Abstract Background Parkinson's disease (PD) patients suffer from progressive gray matter volume (GMV) loss, but whether distinct patterns of atrophy progression exist within PD are still unclear. Objective This study aims to identify subtypes with different rates GMV loss and assess their association clinical progression. Methods included 107 (mean age: 60.06 ± 9.98 years, 70.09% male) baseline ≥ 3-year follow-up structural MRI scans. A linear mixed-effects model was employed the regional loss. Hierarchical cluster analysis conducted explore potential based on individual Clinical score changes were then compared across these subtypes. Results Two identified brain rates. Subtype 1 (n = 63) showed moderate atrophy, notably in prefrontal lateral temporal lobes, while 2 44) had faster brain, particularly region. Furthermore, subtype exhibited deterioration non-motor (MDS-UPDRS-Part Ⅰ, β 1.26 0.18, P 0.016) motor Ⅱ, 1.34 0.20, 0.017) symptoms, autonomic dysfunction (SCOPA-AUT, 1.15 0.22, 0.043), memory (HVLT-Retention, −0.02 0.01, depression (GDS, 0.26 0.083, 0.019) 1. Conclusion The has two progression, which may have implications for developing personalized treatment strategies.

Language: Английский

Citations

2
Nonpharmacological therapies for neurodegenerative disorders DOI
Abdelmonem Siddiq, Shubham Shrestha,

Manisha Das

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 127 - 165

Published: Nov. 29, 2024

Language: Английский

Citations

2
Supplementing Best Care with Specialized Rehabilitation Treatment in Parkinson’s Disease: A Retrospective Study by Different Expert Centers DOI Open Access
Maria Felice Ghilardi, Angelo Quartarone, Alessandro Di Rocco

et al.

Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(10), P. 2999 - 2999

Published: May 20, 2024

Background: This is a retrospective longitudinal study comparing 374 patients with Parkinson's disease (PD) who were treated in centers offering specialized program of enhanced rehabilitation therapy addition to expert outpatient care 387 PD, only received at movement disorders Italy. Methods: The data are from subjects recruited the Outcome Project (POP) six Italian that part multicenter collaboration for quality improvement (the Fresco Network). effects measured baseline and follow-up clinical evaluation Timed-Up-and-Go test (TUG), Disease Questionnaire (PDQ-39), Multidimensional Caregiver Strain Index (MCSI), number falls hospitalizations any cause. We used generalized linear mixed model dependent variables being response variable, which included covariates demographics, evaluation, treatment variables. Results: found underwent had better motor outcome over time than those managed by neurologists but participated community programs exercise other allied health interventions. greatest seen early stages high amount vigorous per week last months. Similar PDQ39, MCSI, falls, hospitalization. Conclusions: Long-term benefits function life PD burden reduction their caregivers can be achieved through systematic

Language: Английский

Citations

1
Imbalance and Falls in Patients with Parkinson’s Disease: Causes and Recent Developments in Training and Sensor-Based Assessment DOI Creative Commons
Veit Mylius,

Elisabeth Zenev,

Caroline Sharon Brook

et al.

Brain Sciences, Journal Year: 2024, Volume and Issue: 14(7), P. 625 - 625

Published: June 22, 2024

Imbalance and falls in patients with Parkinson’s disease (PD) do not only reduce their quality of life but also expectancy. Aging-related symptoms as well disease-specific motor non-motor contribute to these conditions should be treated when appropriate. In addition an active lifestyle, advanced exercise training is useful effective, especially for less medically responsive such freezing gait postural instability at stages. As treadmill non-immersive virtual reality, including dual tasks, significantly reduced the number PD patients, mechanism(s) explaining this effect further investigated. Such research could help select most suitable develop effective protocols based on novel technology. Real-life digital surrogate markers mobility, those describing aspects endurance, performance, complexity specific movements, can improve mobility assessment using wearables.

Language: Английский

Citations

0
Parkinson’s Disease DOI
Caroline M. Tanner, Jill L. Ostrem

New England Journal of Medicine, Journal Year: 2024, Volume and Issue: 391(16), P. 1558 - 1559

Published: Oct. 23, 2024

Language: Английский

Citations

0
Improving quality of care and quality of life for people with Parkinson's disease living in residential care DOI

Sarah Jane Palmer

Nursing and Residential Care, Journal Year: 2024, Volume and Issue: 26(11), P. 1 - 2

Published: Nov. 2, 2024

Sarah Jane Palmer discusses how to improve quality of life among people with Parkinson's disease living in residential care

Language: Английский

Citations

0
The Impact of Physical Activity on Neuroprotection in Neurodegenerative Diseases: A Special Focus on Parkinson’s Disease DOI Creative Commons
Aleksandra Buczek, Paulina Jakubczyk,

Olga Bilczewska

et al.

Quality in Sport, Journal Year: 2024, Volume and Issue: 36, P. 56588 - 56588

Published: Dec. 22, 2024

Aim of the studyThis study examines impact physical activity on neuroprotection in neurodegenerative diseases, focusing Parkinson’s Disease (PD). It evaluates neuroprotective mechanisms, analyzes activity’s role PD progression, assesses various exercise forms’ effectiveness symptoms, and identifies research challenges future directions. Materials methodsA comprehensive literature search was conducted across major databases, prioritizing studies from past 15 years, particularly longitudinal randomized controlled trials. The review critically evaluated specificity, effects symptoms. State knowledgeRegular enhances neuroplasticity, regulates neurotrophic factors, reduces oxidative stress, mitigates inflammation patients. Various forms show managing symptoms potentially slowing disease progression. Challenges remain optimizing interventions for individual patients integrating into management strategies. ConclusionsThe highlights significant PD, demonstrating its potential to manage slow Research gaps persist regarding long-term personalized interventions. Future should focus protocols, investigating synergistic with pharmacological treatments, developing This supports as a valuable adjunctive therapy influencing treatment paradigms disorders.

Language: Английский

Citations

0