Evidence-based consensus guidelines on patient selection and trial stimulation for spinal cord stimulation therapy for chronic non-cancer pain

Regional Anesthesia & Pain Medicine, Journal Year: 2023, Volume and Issue: 48(6), P. 273 - 287

Published: March 30, 2023

Spinal cord stimulation (SCS) has demonstrated effectiveness for neuropathic pain. Unfortunately, some patients report inadequate long-term pain relief. Patient selection is emphasized this therapy; however, the prognostic capabilities and deployment strategies of existing techniques, including an SCS trial, have been questioned. After approval by Board Directors American Society Regional Anesthesia Pain Medicine, a steering committee was formed to develop evidence-based guidelines patient role trial. Representatives professional organizations with clinical expertize were invited participate as members. A comprehensive literature review carried out committee, results organized into narrative reports, which circulated all Individual statements recommendations within each seven sections formulated members voting. We used modified Delphi method wherein drafts member in blinded fashion Comments incorporated subsequent revisions, recirculated voting achieve consensus. Seven total 39 approved 100% consensus from Sections included definitions terminology trial; benefits screening psychosocial characteristics; perceptions on therapy use other predictors conduct trials; evaluation trials minimum criteria success. Recommendations that trial should be performed before definitive implant except anginal (grade B). All must screened objective validated instrument factors, include depression Despite limitations, helps provides opportunity experience therapy. These are expected guide practicing physicians stakeholders not mistaken practice standards. Physicians continue make their best judgment based individual considerations preferences.

Language: Английский

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The Neurostimulation Appropriateness Consensus Committee (NACC)®: Recommendations for Spinal Cord Stimulation Long-Term Outcome Optimization and Salvage Therapy

Neuromodulation Technology at the Neural Interface, Journal Year: 2024, Volume and Issue: 27(6), P. 951 - 976

Published: June 19, 2024

Language: Английский

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Autonomic Nervous System in Bone Remodeling: From Mechanisms to Novel Therapies in Orthopedic Diseases

Orthopaedic Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: March 12, 2025

Recent literature has increasingly demonstrated the significant function of autonomic nerves in regulating physiological and pathological changes associated with skeletal system. Extensive studies have been conducted to understand contribution nervous system (ANS) metabolic homeostasis resistance aseptic inflammation, specifically from viewpoint neurobiology. There plenty on how sympathetic (SNS) parasympathetic (PNS), two main branches ANS, regulate bone remodeling, which is process formation resorption. The following revealed critical neurological pathways that induce alterations cell biology uncover intricate linkages between ANS Furthermore, inspired by connection neuromodulation utilized as a therapeutic method for patients orthopedic diseases: directly influencing it possible alter excitability nerve fibers release neurotransmitters, can lead anti-inflammatory analgesic effects, thereby or indirectly impacting Our work aims review most recent findings impact enhance current understanding interaction bones, explore potential methods could be used treat conditions, drawing attention role

Language: Английский

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Spinal cord stimulation for the treatment of chronic pain

Nature Reviews Neurology, Journal Year: 2024, Volume and Issue: 20(8), P. 447 - 448

Published: July 1, 2024

Language: Английский

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Sensory-substitution based sound perception using a spinal computer–brain interface

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Oct. 22, 2024

Abstract Sensory substitution offers a promising approach to restore lost sensory functions. Here we show that spinal cord stimulation (SCS), typically used for chronic pain management, can potentially serve as novel auditory device. We recruited 13 patients undergoing SCS implantation and translated everyday sound samples into personalized patterns during their trial phase. In identification task—where chance-level performance was 33.3%—participants ( $$n=8$$ n = 8 ) achieved mean accuracy of 72.8% using only input. observed weak positive correlation between bitrate accuracy. A follow-up discrimination task $$n=5$$ 5 confirmed reduced bitrates significantly impaired participants’ ability distinguish consecutive patterns, indicating effective processing additional information at higher bitrates. These findings demonstrate the feasibility existing technology create neural interface prosthesis. Our results pave way future research enhance fidelity, assess long-term training effects, explore integration with other aids comprehensive hearing rehabilitation.

Language: Английский

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Editors’ comments for special edition on neuromodulation for pain syndromes

Regional Anesthesia & Pain Medicine, Journal Year: 2023, Volume and Issue: 48(6), P. 249 - 250

Published: April 20, 2023

The population health implications stemming from the global pain burden are sobering. However, there is tremendous potential and scope for developing introducing new interventional therapies patients in with goal of improving quality their lives. Regional Anesthesia & Pain

Language: Английский

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