40 Hz Visual Stimulation During Sleep Evokes Neuronal Gamma Activity in NREM and REM Stages DOI Creative Commons
Laura Hainke, James Dowsett, Manuel Spitschan

et al.

SLEEP, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

Abstract Study Objectives Visual stimulation (VS) at 40 Hz is being tested as a non-invasive approach against dementias such Alzheimer’s disease. Applying it during sleep could increase the convenience, duration, and efficacy of stimulation. Here, we feasibility VS in proof-of-concept study. Methods Thirty healthy participants underwent one control experimental night polysomnography laboratory. was delivered wakefulness (W), NREM stages 2 3, REM sleep. Results As expected, EEG spectral power increased all four condition, compared to control. It highest W similar across 2, REM, with large medium effect sizes, respectively. Steady-state visually evoked potential (SSVEP) analyses time domain confirmed specificity effect. Secondary revealed that intervention did not impair objective subjective quality beyond first-night Conclusions effectively neuronal gamma activity frequency without degrading quality, supporting this approach. These findings lay groundwork for optimizing gamma-band sensory tool causally study cognitive functions scalable, dementias.

Language: Английский

Editorial on the special issue on neuro-sleep as a complex system DOI Creative Commons
Oxana Semyachkina‐Glushkovskaya, А. Н. Павлов,

Maria Farsari

et al.

The European Physical Journal Special Topics, Journal Year: 2024, Volume and Issue: 233(3), P. 457 - 462

Published: April 23, 2024

Language: Английский

Citations

0
40 Hz Visual Stimulation During Sleep Evokes Neuronal Gamma Activity in NREM and REM Stages DOI Creative Commons
Laura Hainke, James Dowsett, Manuel Spitschan

et al.

SLEEP, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 18, 2024

Abstract Study Objectives Visual stimulation (VS) at 40 Hz is being tested as a non-invasive approach against dementias such Alzheimer’s disease. Applying it during sleep could increase the convenience, duration, and efficacy of stimulation. Here, we feasibility VS in proof-of-concept study. Methods Thirty healthy participants underwent one control experimental night polysomnography laboratory. was delivered wakefulness (W), NREM stages 2 3, REM sleep. Results As expected, EEG spectral power increased all four condition, compared to control. It highest W similar across 2, REM, with large medium effect sizes, respectively. Steady-state visually evoked potential (SSVEP) analyses time domain confirmed specificity effect. Secondary revealed that intervention did not impair objective subjective quality beyond first-night Conclusions effectively neuronal gamma activity frequency without degrading quality, supporting this approach. These findings lay groundwork for optimizing gamma-band sensory tool causally study cognitive functions scalable, dementias.

Language: Английский

Citations

0