Phytoestrogens: Pharmacological Potential and Therapeutic Insights for Urinary Tract Infections

Phytotherapy Research, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 30, 2024

Urinary tract infections (UTIs) are exceptionally common in postmenopausal female or patients with diabetes mellitus nephrolithiasis, carrying substantial burden on and healthcare system. Increasing proportion ongoing spread of antibiotic-resistant pathogens have further debilitated the condition battlefield against UTIs. Lack estrogen may contribute to high inclination UTIs after menopause hormone replacement therapy can mitigate symptoms hot flashes, vaginal dryness UTIs, rationalizing usage analogues treatment prophylaxis Phytoestrogens which comprise flavonoids, coumerins, stilbenes, lignans, natural botanical compounds structural similarity biochemical features. emerged as adjuvant remedy for uropathogenic bacteria even multidrug-resistant ones, multifaceted mechanisms such inhibition adhesion invading ability bacteria, destruction biofilms, synergistically enhancement antibiotics activity. It is plausible propose phytoestrogens potential agents combination other strategies ameliorate challenge multi-drug resistance

Language: Английский

Anticancer potential of osthole: targeting gynecological tumors and breast cancer

Pharmacological Reports, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 2, 2024

Language: Английский