
Toxicologic Pathology, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 13, 2024
Pathology, a fundamental discipline that bridges basic scientific discovery to the clinic, is integral successful drug development. Intrinsically multimodal and multidimensional, anatomic pathology continues be empowered by advancements in molecular digital technologies enabling spatial tissue detection of biomolecules such as genes, transcripts, proteins. Over past two decades, breakthroughs biology automation digitization laboratory processes have enabled implementation higher throughput assays generation extensive data sets from sections biopharmaceutical research development units. It our goal provide readers with some rationale, advice, ideas help establish modern meet emerging needs research. This manuscript provides (1) high-level overview current state future vision for excellence practice (2) shared perspectives on how optimally leverage expertise discovery, toxicologic, translational pathologists effective spatial, molecular, support discovery. captures insights experiences, challenges, solutions laboratories various organizations, including their approaches troubleshooting adopting new technologies.
Language: Английский