Toxoplasma gondii’s Endosymbionts: An Insight into Their Genomic Secrets

Published: Jan. 1, 2025

Language: Английский

---

Evolution of ubiquitin, cytoskeleton, and vesicular trafficking machinery in giant viruses

Journal of Virology, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 11, 2025

ABSTRACT Members of the phylum Nucleocytoviricota , which include “giant viruses” known for their large physical dimensions and genome lengths, are a diverse group dsDNA viruses that infect wide range eukaryotic hosts. The genomes nucleocytoviruses frequently encode signature proteins (ESPs) such as RNA- DNA-processing proteins, vesicular trafficking factors, cytoskeletal components, involved in ubiquitin signaling. Despite prevalence these genes many nucleocytoviruses, timing number gene acquisitions remains unclear. While presence DNA- RNA-processing likely reflects ancient transfers, origins evolutionary history other largely unknown. In this study, we examined distribution subset viral-encoded ESPs (vESPs) widespread nucleocytoviruses. Our results demonstrate most vESPs were acquired multiple times independently by at different time points after emergence supergroups, while viral associated with system exhibited more complex pattern both shallow deep branching clades. This reveals dynamic interplay between co-evoluton eukaryotes viruses, suggesting acquisition cellular processes has occurred through recent horizontal transfers. frequency may provide insight into role functional significance during infection. IMPORTANCE research is pertinent understanding evolution interactions By investigating study transfer patterns, highlighting how acquire allow them to manipulate host processes. Identifying related essential functions provides insights roles infections. work expands our diversity adaptability, contributing valuable knowledge virology biology, offering new perspectives on relationship

Language: Английский

---

Can a microbial community become an evolutionary individual?

Current Opinion in Microbiology, Journal Year: 2025, Volume and Issue: 84, P. 102596 - 102596

Published: Feb. 20, 2025

Microbial communities provide crucial services for human well-being, driving an interest in designing and controlling them towards optimised or novel functions. Unfortunately, promising strategies such as community breeding - sometimes referred to 'directed evolution' 'artificial selection' have shown limited success. A key issue is that microbial do not reliably exhibit heritable variation, limiting their capacity adaptive evolution. In other words, are evolutionary individuals. Here, we overview of the literature on transitions individuality and, with insights from paradigmatic organisms, build a multidimensional space which multispecies characterised by three ecological traits: positive interactions, functional integration, entrenchment. We then place within this space, explore how they can be directed toward increased individuality, discuss perspective help improve our approach breeding.

Language: Английский

---

15 DNA facts

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 30

Published: Jan. 1, 2025

---

Fitness effects of killer virus infection on wild Saccharomyces paradoxus

Fungal ecology, Journal Year: 2025, Volume and Issue: 75, P. 101418 - 101418

Published: March 6, 2025

Language: Английский

---