Chronic unpredictable stress induces anxiety-like behaviors in young zebrafish DOI Creative Commons
Archana Golla,

Henrik Østby,

Florence Kermen

et al.

Scientific Reports, Journal Year: 2020, Volume and Issue: 10(1)

Published: June 25, 2020

Abstract Exposure to stress during early life affects subsequent behaviors and increases the vulnerability adult pathologies, a phenomenon that has been well documented in humans rodents. In this study, we introduce chronic unpredictable protocol adapted young zebrafish, which is an increasingly popular vertebrate model neuroscience research. We exposed zebrafish series of intermittent mild stressors from day 10 17 post-fertilization. The stressed fish showed reduced exploration novel environment one post-stress increased responsiveness dark-light transition two days post-stress, indicative heightened anxiety-related behaviors. stress-induced decrease lasted for at least three returned control levels within week. Moreover, were on average 8% smaller than their siblings All together, our results demonstrate develop growth behavioral alterations akin those observed rodent models.

Language: Английский

Genotypic and phenotypic characteristics of ADGRV1 mutations in four children and functional validation in a zebrafish model DOI
Xiao Xiao, Hao Zheng,

Miao Xiong

et al.

Gene, Journal Year: 2025, Volume and Issue: 942, P. 149246 - 149246

Published: Jan. 16, 2025

Language: Английский

Citations

1
Data-driven modelling of social forces and collective behaviour in zebrafish DOI Creative Commons
Adam Zienkiewicz,

Fabrizio Ladu,

David A. W. Barton

et al.

Journal of Theoretical Biology, Journal Year: 2018, Volume and Issue: 443, P. 39 - 51

Published: Jan. 31, 2018

Language: Английский

Citations

60
Zebrafish models relevant to studying central opioid and endocannabinoid systems DOI
Konstantin A. Demin, Darya A. Meshalkina, Elana V. Kysil

et al.

Progress in Neuro-Psychopharmacology and Biological Psychiatry, Journal Year: 2018, Volume and Issue: 86, P. 301 - 312

Published: March 28, 2018

Language: Английский

Citations

60
Exposure to silver impairs learning and social behaviors in adult zebrafish DOI

Chih-Wei Fu,

Jiun‐Lin Horng, Sok‐Keng Tong

et al.

Journal of Hazardous Materials, Journal Year: 2020, Volume and Issue: 403, P. 124031 - 124031

Published: Sept. 18, 2020

Language: Английский

Citations

51
Chronic unpredictable stress induces anxiety-like behaviors in young zebrafish DOI Creative Commons
Archana Golla,

Henrik Østby,

Florence Kermen

et al.

Scientific Reports, Journal Year: 2020, Volume and Issue: 10(1)

Published: June 25, 2020

Abstract Exposure to stress during early life affects subsequent behaviors and increases the vulnerability adult pathologies, a phenomenon that has been well documented in humans rodents. In this study, we introduce chronic unpredictable protocol adapted young zebrafish, which is an increasingly popular vertebrate model neuroscience research. We exposed zebrafish series of intermittent mild stressors from day 10 17 post-fertilization. The stressed fish showed reduced exploration novel environment one post-stress increased responsiveness dark-light transition two days post-stress, indicative heightened anxiety-related behaviors. stress-induced decrease lasted for at least three returned control levels within week. Moreover, were on average 8% smaller than their siblings All together, our results demonstrate develop growth behavioral alterations akin those observed rodent models.

Language: Английский

Citations

50