Reducing the Phytotoxicity of Tryptanthrin Derivatives for Controlling Plant Bacterial Canker and Wilt Diseases DOI
Mei Zhu, Guiping Ouyang

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Herein, we synthesized 34 novel tryptanthrin derivatives, among which T7NHCO-series compounds showed great antibacterial activity againstXanthomonas axonopodis pv. citri,Pseudomonas syringae actinidiae, andRalstonia solanacearum with EC50 values ranging from 0.26 to 0.56 μg/mL. Meanwhile, these exhibited low cytotoxicity against HEK-293. Additionally, compound T7NHCO can inhibit biofilm formation, damage bacterial morphology, downregulate the expression of chemotaxis-related proteins, cause necrosis, and effectively control citrus kiwifruit canker (the curative protective efficiency is 79.35 88.31%, respectively) diseases. However, a significant phytotoxicity tobacco. Subsequently, based on characteristic tobacco wilt disease being prone outbreak in weakly acidic soil conditions, introduced pH-responsive ZIF-8 drug delivery system. Fortunately, T7NHCO@ZIF-8 nanoparticles noticeable disease. Above all, may be promising green lead agent plant

Language: Английский

Discovery of berberine derivatives@chitosan nanoparticles for controlling plant canker diseases DOI
Mei Zhu, Danping Chen, Cheng‐Peng Li

et al.

Food Hydrocolloids, Journal Year: 2025, Volume and Issue: unknown, P. 111054 - 111054

Published: Jan. 1, 2025

Language: Английский

Citations

0
Reducing the Phytotoxicity of Tryptanthrin Derivatives for Controlling Plant Bacterial Canker and Wilt Diseases DOI
Mei Zhu, Guiping Ouyang

Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

Herein, we synthesized 34 novel tryptanthrin derivatives, among which T7NHCO-series compounds showed great antibacterial activity againstXanthomonas axonopodis pv. citri,Pseudomonas syringae actinidiae, andRalstonia solanacearum with EC50 values ranging from 0.26 to 0.56 μg/mL. Meanwhile, these exhibited low cytotoxicity against HEK-293. Additionally, compound T7NHCO can inhibit biofilm formation, damage bacterial morphology, downregulate the expression of chemotaxis-related proteins, cause necrosis, and effectively control citrus kiwifruit canker (the curative protective efficiency is 79.35 88.31%, respectively) diseases. However, a significant phytotoxicity tobacco. Subsequently, based on characteristic tobacco wilt disease being prone outbreak in weakly acidic soil conditions, introduced pH-responsive ZIF-8 drug delivery system. Fortunately, T7NHCO@ZIF-8 nanoparticles noticeable disease. Above all, may be promising green lead agent plant

Language: Английский

Citations

0