Cureus,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 19, 2024
Esthesioneuroblastomas
(ENBs)
present
unique
diagnostic
and
therapeutic
challenges
due
to
their
rare
complex
clinical
presentation.
In
recent
years,
artificial
intelligence
(AI)
machine
learning
(ML)
have
emerged
as
promising
tools
in
various
medical
specialties,
revolutionizing
accuracy,
treatment
planning,
patient
outcomes.
However,
application
ENBs
remains
relatively
unexplored.
This
comprehensive
literature
review
aims
evaluate
the
current
state
of
AI
ML
technologies
ENB
diagnosis,
radiological
histopathological
imaging,
planning.
By
synthesizing
existing
evidence
identifying
gaps
knowledge,
this
showcase
potential
benefits,
limitations,
future
directions
integrating
into
multidisciplinary
management
ENBs.
Diagnostic and Interventional Radiology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 2, 2024
Although
artificial
intelligence
(AI)
methods
hold
promise
for
medical
imaging-based
prediction
tasks,
their
integration
into
practice
may
present
a
double-edged
sword
due
to
bias
(i.e.,
systematic
errors).AI
algorithms
have
the
potential
mitigate
cognitive
biases
in
human
interpretation,
but
extensive
research
has
highlighted
tendency
of
AI
systems
internalize
within
model.This
fact,
whether
intentional
or
not,
ultimately
lead
unintentional
consequences
clinical
setting,
potentially
compromising
patient
outcomes.This
concern
is
particularly
important
imaging,
where
been
more
progressively
and
widely
embraced
than
any
other
field.A
comprehensive
understanding
at
each
stage
pipeline
therefore
essential
contribute
developing
solutions
that
are
not
only
less
biased
also
applicable.This
international
collaborative
review
effort
aims
increase
awareness
imaging
community
about
importance
proactively
identifying
addressing
prevent
its
negative
from
being
realized
later.The
authors
began
with
fundamentals
by
explaining
different
definitions
delineating
various
sources.Strategies
detecting
were
then
outlined,
followed
techniques
avoidance
mitigation.Moreover,
ethical
dimensions,
challenges
encountered,
prospects
discussed.
European Journal of Pharmacology,
Journal Year:
2025,
Volume and Issue:
989, P. 177258 - 177258
Published: Jan. 9, 2025
The
IUPHAR
Education
Section's
Pharmacology
Project
(PEP;
www.pharmacologyeducation.org)
provides
an
open-access,
peer-reviewed
platform
to
support
pharmacology
education
globally.
Launched
in
2016,
PEP
offers
a
comprehensive
range
of
freely
accessible,
resources,
including
extensive
topic
summaries
with
links
videos,
slide
sets,
and
other
media
curated
by
pharmacologists
catering
diverse
learners'
needs.
This
paper
update
on
PEP's
growth,
providing
analytics
user
engagement
feedback.
averages
20,000
visits
per
month,
peak
50,000
during
the
COVID-19
pandemic.
Engagement
rates
are
approximately
40%,
indicating
robust
interaction
content.
Feedback
from
115
users
spanning
31
countries
praises
quality
quantity
resources
ease
navigation
through
website.
Comparisons
traditional
used
highlight
advantages
accessibility
peer
review.
Examples
use
provided,
emphasizing
active
self-directed
learning
methodologies.
discussion
includes
challenges
maintaining
expanding
platform,
such
as
funding
content
curation,
outlines
strategies
for
sustainable
development,
role
that
artificial
intelligence
may
play.
is
valuable
resource
contemporary
plays
vital
advancing
field
Frontiers in Digital Health,
Journal Year:
2025,
Volume and Issue:
7
Published: Feb. 25, 2025
Mental
health
disorders
and
cognitive
decline
are
pressing
global
concerns,
increasing
the
demand
for
non-pharmacological
interventions
targeting
emotional
dysregulation,
memory
deficits,
neural
dysfunction.
This
review
systematically
examines
three
promising
methodologies-music
therapy,
brainwave
entrainment
(binaural
beats,
isochronic
tones,
multisensory
stimulation),
their
integration
into
a
unified
therapeutic
paradigm.
Emerging
evidence
indicates
that
music
therapy
modulates
affect,
reduces
stress,
enhances
cognition
by
engaging
limbic,
prefrontal,
reward
circuits.
Brainwave
entrainment,
particularly
within
gamma
frequency
range
(30-100
Hz),
facilitates
oscillatory
patterns
linked
to
relaxation,
concentration,
memory,
with
40
Hz
showing
promise
enhancement,
albeit
individual
variability.
Synchronized
stimulation,
combining
auditory
visual
inputs
at
frequencies,
has
demonstrated
potential
in
enhancing
supporting
integrity,
Alzheimer's
disease.
However,
challenges
such
as
patient
response
variability,
lack
of
standardization,
scalability
hinder
widespread
implementation.
Recent
research
suggests
synergistic
application
these
modalities
may
optimize
outcomes
leveraging
complementary
mechanisms.
To
actualize
this,
AI-driven
biofeedback,
enabling
real-time
physiological
assessment
individualized
adjustments-such
tailoring
musical
complexity,
components-emerges
solution.
adaptive
model
treatment
accessibility
consistency
while
maximizing
long-term
efficacy.
Although
early
stages,
preliminary
highlights
its
transformative
reshaping
strategies.
Advancing
this
field
requires
interdisciplinary
research,
rigorous
evaluation,
ethical
data
stewardship
develop
innovative,
patient-centered
solutions
mental
rehabilitation.
Journal of Pain Research,
Journal Year:
2025,
Volume and Issue:
Volume 18, P. 1021 - 1033
Published: Feb. 1, 2025
Artificial
Intelligence
(AI)
has
the
potential
to
optimize
personalized
treatment
tools
and
enhance
clinical
decision-making.
However,
biases
in
AI,
arising
from
sex,
race,
socioeconomic
status
(SES),
statistical
methods,
can
exacerbate
disparities
pain
management.
This
narrative
review
examines
these
proposes
strategies
mitigate
them.
A
comprehensive
literature
search
across
databases
such
as
PubMed,
Google
Scholar,
PsycINFO
focused
on
AI
applications
management
sources
of
biases.
Sex
racial
often
stem
societal
stereotypes,
underrepresentation
females,
overrepresentation
European
ancestry
patients
trials,
unequal
access
caused
by
systemic
racism,
leading
inaccurate
assessments
misrepresentation
data.
SES
reflect
differential
healthcare
resources
incomplete
data
for
lower
individuals,
resulting
larger
prediction
errors.
Statistical
biases,
including
sampling
measurement
further
affect
reliability
algorithms.
To
ensure
equitable
delivery,
this
recommends
employing
specific
fairness-aware
techniques
reweighting
algorithms,
adversarial
debiasing,
other
methods
that
adjust
training
minimize
bias.
Additionally,
leveraging
diverse
perspectives-including
insights
patients,
clinicians,
policymakers,
interdisciplinary
collaborators-can
development
fair
interpretable
systems.
Continuous
monitoring
inclusive
collaboration
are
essential
addressing
harnessing
AI's
improve
outcomes
populations.
Diagnostics,
Journal Year:
2025,
Volume and Issue:
15(7), P. 822 - 822
Published: March 24, 2025
Background:
The
implementation
of
radiological
artificial
intelligence
(AI)
solutions
remains
challenging
due
to
limitations
in
existing
testing
methodologies.
This
study
assesses
the
efficacy
a
comprehensive
methodology
for
performance
and
monitoring
commercial-grade
mammographic
AI
models.
Methods:
We
utilized
combination
retrospective
prospective
multicenter
approaches
evaluate
neural
network
based
on
Faster
R-CNN
architecture
with
ResNet-50
backbone,
trained
dataset
3641
mammograms.
encompassed
functional
calibration
testing,
coupled
routine
technical
clinical
monitoring.
Feedback
from
testers
radiologists
was
relayed
developers,
who
made
updates
model.
test
comprised
112
medical
organizations,
representing
10
manufacturers
mammography
equipment
encompassing
593,365
studies.
evaluation
metrics
included
area
under
curve
(AUC),
accuracy,
sensitivity,
specificity,
defects,
assessment
scores.
Results:
results
demonstrated
significant
enhancement
model's
through
collaborative
efforts
among
testers,
radiologists.
Notable
improvements
functionality,
diagnostic
stability.
Specifically,
AUC
rose
by
24.7%
(from
0.73
0.91),
accuracy
improved
15.6%
0.77
0.89),
sensitivity
grew
37.1%
0.62
0.85),
specificity
increased
10.7%
0.84
0.93).
average
proportion
defects
declined
9.0%
1.0%,
while
score
63.4
72.0.
Following
2
years
9
months
solution
integrated
into
compulsory
health
insurance
system.
Conclusions:
multi-stage,
lifecycle-based
substantial
potential
software
integration
practice.
Key
elements
this
include
robust
requirements,
continuous
updates,
systematic
feedback
collection
radiologists,