Modulating culture method promotes the production of disulfide-linked Resorcylic acid lactone dimers with anti-proliferative activity DOI
MeiLan K. Han, Yingjie Zhao, Sen Pang

et al.

Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 108418 - 108418

Published: March 1, 2025

Language: Английский

Natural sulfur compounds in mental health and neurological disorders: insights from observational and intervention studies DOI Creative Commons

Apeksha Rana,

Ashutosh Katiyar,

Alok Arun

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12

Published: April 9, 2025

Over the years, global disease burden of neurological disorders (NDs) and mental (MDs) has significantly increased, making them one most critical concerns challenges to human health. In pursuit novel therapies against MD ND, there been a growing focus on nutrition Dietary sulfur, primarily derived from various natural sources, plays crucial role in numerous physiological processes, including brain function. This review offers an overview chemical composition several sources sulfur-rich substances such as isothiocyanates, sulforaphane, glutathione, taurine, sulfated polysaccharides, allyl sulfides, sulfur-containing amino acids, all which have neuroprotective properties. A multitude studies documented that consuming foods are high sulfur enhances function by improving cognitive parameters reduces severity neuropathology exhibiting antioxidant anti-inflammatory properties at molecular level. addition, compounds repairing endothelial dysfunction, compromising blood-brain barrier cerebral blood flow, here. Furthermore, this covers encouraging results supplementing diets many animal models clinical investigations, along with their targets MD, schizophrenia, depression, anxiety, bipolar disorder, autism spectrum Alzheimer's (AD), Parkinson's (PD), Amyotrophic Lateral Sclerosis (ALS), Multiple (MS). The prospects show great promise they potential applications nutraceuticals, medicines, functional enhance prevent diseases. However, additional research is required clarify mechanisms it works, its bioavailability, evaluate long-term safety for broad use.

Language: Английский

Citations

0
Endophytic Fungi as a Promising Source for Sulfur-Containing Compounds DOI
Amer M. Abdelaziz, Mohamed S. Attia, Ahmed S. Doghish

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Role of the sulfur-containing amino acid-ROS axis in cancer chemotherapeutic drug resistance DOI
Bingli Wu, Yinwei Cheng, Liyan Li

et al.

Drug Resistance Updates, Journal Year: 2025, Volume and Issue: unknown, P. 101238 - 101238

Published: March 1, 2025

Language: Английский

Citations

0
Thiochromenes and thiochromanes: a comprehensive review of their diverse biological activities and structure–activity relationship (SAR) insights DOI Creative Commons

Jatin Jatin,

Solai Murugappan,

Shivani Kirad

et al.

RSC Medicinal Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Medicinal potential of thiochromene and thiochromane scaffolds, highlighting their importance in various diseases.

Language: Английский

Citations

0
Modulating culture method promotes the production of disulfide-linked Resorcylic acid lactone dimers with anti-proliferative activity DOI
MeiLan K. Han, Yingjie Zhao, Sen Pang

et al.

Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 108418 - 108418

Published: March 1, 2025

Language: Английский

Citations

0