Efficacy and safety of acupuncture treatment for fatigue after COVID-19 infection: study protocol for a pilot randomized sham-controlled trial DOI Creative Commons
Sung-A Kim, Jisu Lee, Tae-Gon Kim

et al.

Frontiers in Neurology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 15, 2023

Background As the coronavirus disease 2019 (COVID-19) pandemic has spread globally, its sequelae, called Long COVID, have persisted, troubling patients worldwide. Although fatigue is known to be most frequent among COVID symptoms, mechanism and treatment not been clearly demonstrated. In 2022, we conducted a preliminary prospective case series found that acupuncture moxibustion were feasible interventions for fatigue. This study pilot patient-assessor-blinded randomized sham-controlled trial evaluate efficacy safety of with persisted at least 4 weeks after recovery from COVID-19. Methods Thirty will recruited randomly assigned either or sham groups. Treatment thrice week both groups during weeks. The primary outcome acupuncture, including numeric rating scale (NRS), brief inventory (BFI), severity (FSS), adverse event evaluation. Secondary outcomes evaluation improvement in comorbid symptoms feasibility variables. Outcome variables assessed before treatment, 8 completion. Discussion results this used clarify persistent COVID. Additionally, design was validated provide evidence future full-scale controlled trials. Clinical registration : identifier: KCT0008656 https://cris.nih.go.kr/cris/search/detailSearch.do?seq=24785&search_page=L .

Language: Английский

Patient-Related Metadata Reported in Sequencing Studies of SARS-CoV-2: Protocol for a Scoping Review and Bibliometric Analysis DOI Creative Commons
Karen O’Connor, Davy Weissenbacher, Amir Elyaderani

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: July 16, 2023

There has been an unprecedented effort to sequence the SARS-CoV-2 virus and examine its molecular evolution. This facilitated by availability of publicly accessible databases, Global Initiative on Sharing All Influenza Data (GISAID) GenBank, which collectively hold millions records. Genomic epidemiology, however, seeks go beyond phylogenetic analysis linking genetic information patient characteristics disease outcomes, enabling a comprehensive understanding transmission dynamics impact.While these repositories include fields reflecting patient-related metadata for given sequence, inclusion demographic clinical details is scarce. The extent reported in published sequencing studies quality remains largely unexplored.

Language: Английский

Citations

0
Efficacy and safety of acupuncture treatment for fatigue after COVID-19 infection: study protocol for a pilot randomized sham-controlled trial DOI Creative Commons
Sung-A Kim, Jisu Lee, Tae-Gon Kim

et al.

Frontiers in Neurology, Journal Year: 2023, Volume and Issue: 14

Published: Nov. 15, 2023

Background As the coronavirus disease 2019 (COVID-19) pandemic has spread globally, its sequelae, called Long COVID, have persisted, troubling patients worldwide. Although fatigue is known to be most frequent among COVID symptoms, mechanism and treatment not been clearly demonstrated. In 2022, we conducted a preliminary prospective case series found that acupuncture moxibustion were feasible interventions for fatigue. This study pilot patient-assessor-blinded randomized sham-controlled trial evaluate efficacy safety of with persisted at least 4 weeks after recovery from COVID-19. Methods Thirty will recruited randomly assigned either or sham groups. Treatment thrice week both groups during weeks. The primary outcome acupuncture, including numeric rating scale (NRS), brief inventory (BFI), severity (FSS), adverse event evaluation. Secondary outcomes evaluation improvement in comorbid symptoms feasibility variables. Outcome variables assessed before treatment, 8 completion. Discussion results this used clarify persistent COVID. Additionally, design was validated provide evidence future full-scale controlled trials. Clinical registration : identifier: KCT0008656 https://cris.nih.go.kr/cris/search/detailSearch.do?seq=24785&search_page=L .

Language: Английский

Citations

0