Efficacy of Photobiomodulation Therapy Utilizing 808 nm and 660 nm Alone and in Combination for Treatment of Paresthesia in Rats DOI Creative Commons

Ehsan Hajesmaelzade,

Mohammad Mohammadi, Sina Kakooei

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 13(1), P. 65 - 65

Published: Dec. 30, 2024

Background/Objectives: This study assessed the efficacy of photobiomodulation therapy (PBM) by 808 nm and 660 alone in combination for treatment paresthesia rats. Methods: animal was conducted on 36 adult male Wistar After general anesthesia, facial nerve right side face rats surgically exposed pinched, returned place, sutured. The were randomly assigned to six groups (n = 6) (I) no-intervention (control), (II) no-laser, (III) laser (250 mW, 4 W/cm2, 20 s, 8 J/cm2, (IV) (150 0.25 32 (V) plus with original settings, (VI) half time energy density. 16 days, a biopsy sample taken from injury site underwent histological, histometric, immunohistochemical assessments. Results: Significantly lower edema congestion seen combined group settings (p < 0.05); this had no significant difference control regarding degenerative changes fibers Schwann cells > 0.05). nm, groups, significantly accumulation inflammatory number blood vessels than that no-laser Conclusions: results showed positive PBM lasers resolution inflammation reduction fibers.

Language: Английский

The Potential Role of Adipose-Derived Stem Cells in Regeneration of Peripheral Nerves DOI Creative Commons
PM Sunil, Sivan Padma Priya, Nada Tawfig Hashim

et al.

Neurology International, Journal Year: 2025, Volume and Issue: 17(2), P. 23 - 23

Published: Feb. 6, 2025

Peripheral nerve injuries are common complications in surgical and dental practices, often resulting functional deficiencies reduced quality of life. Current treatment choices, such as autografts, have limitations, including donor site morbidity suboptimal outcomes. Adipose-derived stem cells (ADSCs) shown assuring regenerative potential due to their accessibility, ease harvesting propagation, multipotent properties. This review investigates the therapeutic ADSCs peripheral regeneration, focusing on use bioengineered conduits supportive microenvironments. The analysis is constructed published case reports, organized reviews, clinical trials from Phase I III that investigate managing injuries, emphasizing both orofacial applications. findings highlight advantages promoting secretion angiogenic neurotrophic factors, support for cellular persistence, supplementing scaffold-based tissue repair. capabilities offer a novel approach augmenting repair recovery. accessibility adipose minimally invasive nature ADSC further encourage its prospective application an autologous cell source medicine. Future research needed ascertain standardized protocols optimize outcomes, paving way become mainstay regeneration.

Language: Английский

Citations

0
Lingual plate thickness influences cortical bone injury during lower third molar extraction: A cone beam computed tomography study DOI
Rafael Cardoso, Camila Silvério Carvalho Vieira,

Davisson Alves Pereira

et al.

Oral and Maxillofacial Surgery, Journal Year: 2025, Volume and Issue: 29(1)

Published: April 21, 2025

Language: Английский

Citations

0
Efficacy of Photobiomodulation Therapy Utilizing 808 nm and 660 nm Alone and in Combination for Treatment of Paresthesia in Rats DOI Creative Commons

Ehsan Hajesmaelzade,

Mohammad Mohammadi, Sina Kakooei

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 13(1), P. 65 - 65

Published: Dec. 30, 2024

Background/Objectives: This study assessed the efficacy of photobiomodulation therapy (PBM) by 808 nm and 660 alone in combination for treatment paresthesia rats. Methods: animal was conducted on 36 adult male Wistar After general anesthesia, facial nerve right side face rats surgically exposed pinched, returned place, sutured. The were randomly assigned to six groups (n = 6) (I) no-intervention (control), (II) no-laser, (III) laser (250 mW, 4 W/cm2, 20 s, 8 J/cm2, (IV) (150 0.25 32 (V) plus with original settings, (VI) half time energy density. 16 days, a biopsy sample taken from injury site underwent histological, histometric, immunohistochemical assessments. Results: Significantly lower edema congestion seen combined group settings (p < 0.05); this had no significant difference control regarding degenerative changes fibers Schwann cells > 0.05). nm, groups, significantly accumulation inflammatory number blood vessels than that no-laser Conclusions: results showed positive PBM lasers resolution inflammation reduction fibers.

Language: Английский

Citations

0