Sinusoidal Large B‐Cell Lymphoma: A Cytologic Mimic of Carcinoma and Intravascular Large B‐Cell Lymphoma

Diagnostic Cytopathology, Journal Year: 2025, Volume and Issue: unknown

Published: March 6, 2025

Sinusoidal large B-cell lymphoma (SLBCL) is a rare morphologic variant of diffuse that associated with poor outcomes. The diagnosis SLBCL may be challenging due to its unique features on cytologic preparation and histologic section. This case report describes the incidental focus comparative cyto-histologic findings.

Language: Английский

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Diagnostic Category: Suspicious for Malignancy

Cytopathology, Journal Year: 2025, Volume and Issue: unknown

Published: April 26, 2025

ABSTRACT The suspicious for malignancy category is used by pathologists to indicate a certain degree of uncertainty but still able convey the treating physician risk stratification deferred diagnosis. can be in vast possibility cytomorphological features and clinical scenarios. Suspicious often when there an insufficient number neoplastic cells establishment final diagnosis, many situations, may abundant discrepant with presentation. In addition, pathologist must aware mimickers that, present, prompt use category. Therefore, need better illustrations category, its pitfalls suggestions on upgraded more definite diagnosis using ancillary studies, even scant material.

Language: Английский

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Diagnostic Accuracy of Fine-Needle Aspiration Cytology in Cervical Lymphadenopathies at a Tertiary Care Center in the Kingdom of Bahrain

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: June 11, 2024

Introduction Fine-needle aspiration cytology (FNAC) has become widely used as a first-line diagnostic tool in the evaluation of cervical lymphadenopathies (LADs). However, there are conflicting reports regarding its accuracy differentiating between malignant and benign pathologies. In this study, we aim to determine reliability FNAC distinguishing pathologies causing LAD. Methods This is cross-sectional study reviewing electronic medical records all patients who underwent both excisional biopsy LADs January 2016 December 2023 at tertiary care center Kingdom Bahrain. A comparison was conducted cytopathological results obtained by histopathological FNAC. Results period, 83 patient were reviewed included data analysis. yielded sensitivity 89.3%, specificity 55.6%, positive predictive value (PPV) 72.4%, negative (NPV) 80.0%, an overall 74.7% diagnosing LADs. Conclusion Despite being accessible, convenient, cost-effective, it certain limitations that can restrict lymphomas. We recommend further studies research these possible tools, such ancillary testing, may be useful overcoming them.

Language: Английский

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Cytopathological Pattern of Lymphadenopathy in North Kordofan, Sudan

Saudi Journal of Biomedical Research, Journal Year: 2024, Volume and Issue: 9(06), P. 125 - 129

Published: Aug. 20, 2024

Background: Lymphadenopathy is a frequently encountered and clinically relevant condition that can have several causes, including curable infections or cancerous growths. This study was done to analyze the different cytopathological patterns observed in fine-needle aspiration cytology (FNAC) of patients with lymphadenopathy. Methodology: In this retrospective study, we present findings comprehensive analysis on 70 cases lymphadenopathy North Kordofan State. Our aim investigate frequency underlying causes lymph node enlargement across age groups, as well diverse associated lymphadenopathies. Results: The population comprised 43 males 27 females, ranging from 6 78 years, mean 50.6 years. Among cases, 40 were determined be benign. Out these, 31 diagnosed tuberculosis 9 classified benign aspirates, which included reactive hyperplasia vascular lesions. remaining 30 reported malignant. 12 identified metastatic carcinoma, 10 non-Hodgkin lymphoma, 4 breast cancer, large-cell anaplastic lymphoma. Conclusion: Benign tumors are predominant components FNAC valuable method for examining

Language: Английский

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Navigating the Diagnostic Challenges in Lymph Node Cytology: The Case of Reactive Hyperplasia

Cytopathology, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 5, 2024

ABSTRACT Fine needle cytology (FNC) is a pivotal diagnostic tool for distinguishing between benign and malignant lymphadenopathies mainly because of its minimal invasiveness, cost‐effectiveness accuracy. A major requirement maximising accuracy proper sample management aspirated cellular material. In this process, the morphological evaluation adequate smears paramount, guiding cytopathologists in selection appropriate ancillary tests through recognition cell size patterns distribution. Here, we describe peculiar ‘concentric ovals distribution pattern’, frequently observed FNC reactive lymph nodes, which may represent an aid cytological diagnosis hyperplasia.

Language: Английский

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