Genome wide locus-specific ancestry analysis revealed adaptive admixtures in crossbred cattle of India DOI Creative Commons

Rangasai Chandra Goli,

Kiyevi G Chishi,

Karan Mahar

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 16, 2025

Crossbreeding in India has been widely adopted to address low sustainability and poor productivity non-descript cattle. This study analyzed Vrindavani (VRI) crossbred cattle their parental populations (Holstein Friesian (HOL), Jersey (JER), Brown Swiss (BSW), Hariana (HAR) using SNP data characterize locus-specific ancestry VRI's genome along with admixture proportions population stratification. Admixture analysis showed VRI have 67.3% HOL, 20.1% HAR, 8.5% JER, 4% BSW ancestry. Locus-specific estimation identified regions adaptive admixtures, which can be defined as admixed genomic favored by evolutionary forces increased frequencies, revealed 79.7% Bos taurus 20.3% indicus Notably, on chromosome (chr) 2, 3, 4, 5, 7, 10, 12, 13, 14, 16, 17, 19, 20, 21, 22, 23, 24 were associated disease resistance contributed indicine chr 1, 6, 9, 11, 15, 18, 27, 28 related production taurine The concluded that contributes higher milk yield crosses, while confers adaptability tropical climates. comprehensive suggests inheritance enhances yield, a balance traits is essential for resilience. Understanding patterns aid refining breeding strategies selectively promoting beneficial alleles. Future advancements tools may enable controlled of desirable traits, maximizing heterosis structured programs sustainable production.

Language: Английский

X-linked signatures of positive selection and adaptive genetic plasticity shaping high-altitude resilience in Indian Changthangi sheep DOI

Rangasai Chandra Goli,

Karan Mahar,

Kiyevi G Chishi

et al.

Small Ruminant Research, Journal Year: 2025, Volume and Issue: unknown, P. 107492 - 107492

Published: March 1, 2025

Language: Английский

Citations

0
Rethinking River Buffalo Domestication Through the Lens of Population Genetics Tools: Mehsana Buffalo Is a Unique Population DOI

Rangasai Chandra Goli,

Kiyevi G Chishi,

Karan Mahar

et al.

OMICS A Journal of Integrative Biology, Journal Year: 2025, Volume and Issue: unknown

Published: April 15, 2025

Riverine buffalo domestication likely occurred around 6300 years ago in Northwestern India. Murrah and Surti are important breeds that originated this region the gene flow from these buffaloes to Mehsana has long been proposed. However, extent which ancestry diffused across not investigated thoroughly. Therefore, we global local of Indian using double digest restriction-site associated DNA sequencing data. Principal component analysis, admixture dating, three population tests revealed with statistical significance is a unique population. Hence, hypothesis crossbreed between supported by findings. noticed some individuals Mehsana, 6 out 15, were admixed having 41% Murrah-specific 11% Surti-specific ancestry. Local post-admixture selection signatures (PASS) PASS genome, is, on Bubalus bubalis autosomes (BBA), 1-23 linked BBA, 24 Murrah. Interestingly, upon functional enrichment signatures, several adaptation-related genes pathways ascertained Surti, while Murrah-derived regions featured involved fatty acid synthesis (Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2)) milk production. Based infer introgression genome into happened recent times ancient generations. The finding an independent highlights importance recognizing distinct genetic lineages domesticated species. This implications for reevaluating origins uniqueness other livestock often assumed be hybrids. Practically, findings open up new avenues selective breeding preserve traits such as disease resistance, adaptability, production efficiency. Further studies larger samples called for.

Language: Английский

Citations

0
Genome wide locus-specific ancestry analysis revealed adaptive admixtures in crossbred cattle of India DOI Creative Commons

Rangasai Chandra Goli,

Kiyevi G Chishi,

Karan Mahar

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: May 16, 2025

Crossbreeding in India has been widely adopted to address low sustainability and poor productivity non-descript cattle. This study analyzed Vrindavani (VRI) crossbred cattle their parental populations (Holstein Friesian (HOL), Jersey (JER), Brown Swiss (BSW), Hariana (HAR) using SNP data characterize locus-specific ancestry VRI's genome along with admixture proportions population stratification. Admixture analysis showed VRI have 67.3% HOL, 20.1% HAR, 8.5% JER, 4% BSW ancestry. Locus-specific estimation identified regions adaptive admixtures, which can be defined as admixed genomic favored by evolutionary forces increased frequencies, revealed 79.7% Bos taurus 20.3% indicus Notably, on chromosome (chr) 2, 3, 4, 5, 7, 10, 12, 13, 14, 16, 17, 19, 20, 21, 22, 23, 24 were associated disease resistance contributed indicine chr 1, 6, 9, 11, 15, 18, 27, 28 related production taurine The concluded that contributes higher milk yield crosses, while confers adaptability tropical climates. comprehensive suggests inheritance enhances yield, a balance traits is essential for resilience. Understanding patterns aid refining breeding strategies selectively promoting beneficial alleles. Future advancements tools may enable controlled of desirable traits, maximizing heterosis structured programs sustainable production.

Language: Английский

Citations

0