Utility of Cardiovascular CT in Ischemic Heart Disease

Echocardiography, Journal Year: 2025, Volume and Issue: 42(1)

Published: Jan. 1, 2025

ABSTRACT Cardiac computed tomography angiography (CCTA) has acquired a pivotal role in modern cardiology. It represents the gold standard for noninvasive coronary imaging. Moreover, CCTA permits comprehensive evaluation of atheromatic burden and plaque composition. This study aims to review impact across different presentations ischemic heart disease, from primary prevention patients requiring revascularization.

Language: Английский

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High-Risk Plaque Characteristics in Patients with Suspected Stable Coronary Artery Disease and Impaired Glucose Tolerance: A Coronary Computed Tomography Angiography Study

Journal of Cardiovascular Development and Disease, Journal Year: 2025, Volume and Issue: 12(2), P. 37 - 37

Published: Jan. 22, 2025

Impaired glucose tolerance (IGT), a prediabetic state, is known risk factor for coronary artery disease (CAD). Low-attenuation plaque (LAP) lesions are associated with high of events. We aimed to evaluate high-risk characteristics in LAP between patients IGT and normal (NGT) suspected stable CAD. Coronary computed tomography angiography (CCTA) identified assessed volumes, burdens, features. Glycemic was stratified using oral tests. Among 148 patients, 202 were identified, 93 classified as NGT 55 IGT. Patients had significantly higher prevalence compared (p = 0.007). volume (16.46 ± 12.52 mm3) (12.66 9.72 mm3, p 0.01), but this association did not persist multivariate analysis. The burden greater (10.79 6.84%) than (8.62 5.93%, 0.02), the napkin-ring sign more frequent (12%) versus (5%, 0.02); these associations remained significant frequency signs. These findings may help explain common occurrence prediabetes acute myocardial infarction.

Language: Английский

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Protective effects of turmeric (Curcuma longa L.) supplementation on oxidative stress and metabolic parameters in rats with high-fructose diet-induced metabolic syndrome

Nutrire, Journal Year: 2025, Volume and Issue: 50(1)

Published: Feb. 3, 2025

Language: Английский

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Suboptimal Control of Small Dense Low‐Density Lipoprotein Cholesterol Is Associated With Coronary Plaque Progression: An Intravascular Ultrasound Study

Journal of the American Heart Association, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Plaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. Small dense low-density lipoprotein cholesterol (sdLDL-C) considered as the most atherogenic lipoprotein. This study aims to investigate relationship sdLDL-C level PP in patients with stable coronary artery disease. We conducted a retrospective analysis of 146 lesions 86 by repeat intravascular ultrasound examinations from January 2020 May 2023. was determined increases percent atheroma volume, defined volume proportion occupied entire vascular wall, ≥5% during follow-up. Time-averaged values were calculated for all cardiometabolic parameters including sdLDL-C. Multivariate logistic regression performed interrogate association time-averaged PP. During median follow-up 12.6 months, found 65 (44.5%), mean changes 4.1%±10.2%. A positive correlation observed total (Pearson r=0.29, P=0.006), especially diabetic r=0.58, P<0.001). After multivariate adjustment, every 0.1-mmol/L increase conferred 1.2-fold increased risk Our findings suggest that an independent factor Intensive control along other factors should be mitigate improve cardiovascular outcomes.

Language: Английский

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Consequences of Hypertension

IntechOpen eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: April 18, 2025

Through complex pathways that continue to be elucidated, hypertension damages tissues, organs and systems, has become a public health risk factor disease of global importance. Its mechanisms, complications on organ their salient features, are outlined highlight how they could understood inform contemplating clinical, policy strategies. Among these are: cardiac including coronary artery atherosclerosis, myocardial ischaemia hypertrophy its complications; cerebrovascular haemorrhagic ischaemic stroke; renal leading end stage failure; vascular aortic aneurysm diffuse peripheral arterial disease; wide range ocular complete permanent vision loss. Ultimately, premature death can complicate untreated hypertension. More is needed implement as the issue it address consequences.

Language: Английский

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Predictors of Rapid Coronary Plaque Progression Measured by CT: More Opportunities to Optimize Prevention

Circulation Cardiovascular Imaging, Journal Year: 2024, Volume and Issue: 17(7)

Published: July 1, 2024

Language: Английский

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Metabolic Effects of Loquat Juice (Eriobotrya japonica Lindl Mkarkeb Variety) on Lipid Homeostasis, Liver Steatosis, and Oxidative Stress in Hyperlipidemic Mice Fed a High-Fat–High-Fructose Diet

Metabolites, Journal Year: 2024, Volume and Issue: 14(11), P. 592 - 592

Published: Nov. 2, 2024

Loquat fruit is consumed for its flavorful taste and a rich array of health-promoting compounds like phenolics, flavonoids, carotenoids. This study aimed at the biochemical characterization fresh juice from Moroccan

Language: Английский

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Association of Low-Attenuation Plaque with Impaired Glucose Tolerance and Type 2 Diabetes Mellitus in Patients with Suspected Coronary Artery Disease

Biomedicines, Journal Year: 2024, Volume and Issue: 13(1), P. 28 - 28

Published: Dec. 26, 2024

The aim of this study was to evaluate the differences in plaque composition and burden between normal glycemic status (NGS) dysglycemia expressed as impaired glucose tolerance (IGT) type 2 diabetes mellitus (T2DM). Clinically indicated coronary computed tomography angiography used patients with suspected artery disease (CAD). An oral test performed assess status. Patients were stratified NGS, IGT, T2DM. Plaque volumes quantified using validated software, further compositional measurements low-attenuation, non-calcified, calcified burden. Of 355 CAD, 220 had 92 diagnosed 43 known Low-attenuation volume significantly higher IGT (209 mm3, p < 0.02) T2DM (243 = 0.005) compared NGS (166 mm3). Total similar all groups, but a greater low-attenuation seen (p 0.03) NGS. multivariate linear regression model adjusted for clinical risk factors showed that those 0.03). Interestingly, no significant burdens observed both univariate analyses. Dysglycemia, including mellitus, associated increased demonstrated T2DM, underscoring need early metabolic intervention.

Language: Английский

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Imaging detected coronary and carotid atherosclerosis in the general population: is prevalence still different between sexes?

European Heart Journal - Cardiovascular Imaging, Journal Year: 2024, Volume and Issue: 25(12), P. 1673 - 1674

Published: Aug. 16, 2024

Journal Article Accepted manuscript Imaging Detected Coronary and Carotid atherosclerosis in the general population: is prevalence still different between sexes? Get access Riccardo Liga, MD, PhD, PhD Cardiology Division, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy https://orcid.org/0000-0002-9964-5604 Search for other works by this author on: Oxford Academic PubMed Google Scholar Mariaelena Occhipinti, Department, Fondazione Toscana Gabriele Monasterio, Danilo Neglia, Cardiovascular [email protected] https://orcid.org/0000-0003-0016-9538 European Heart - Imaging, jeae218, https://doi.org/10.1093/ehjci/jeae218 Published: 16 August 2024 history Received: 30 July Accepted: 15

Language: Английский

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