JACC Advances, Journal Year: 2024, Volume and Issue: 4(1), P. 101460 - 101460
Published: Dec. 13, 2024
Language: Английский
Biomedicines, Journal Year: 2025, Volume and Issue: 13(1), P. 241 - 241
Published: Jan. 20, 2025
Comorbidities related to cardiovascular disease (CVD) and environmental pollution have emerged as serious concerns. The exposome concept underscores the cumulative impact of factors, including climate change, air pollution, chemicals like PFAS, heavy metals, on health. Chronic exposure these pollutants contributes inflammation, oxidative stress, endothelial dysfunction, further exacerbating global burden CVDs. Specifically, carbon monoxide (CO), ozone, particulate matter (PM2.5), nitrogen dioxide (NO2), sulfur (SO2), pesticides, micro- nanoplastics been implicated in morbidity mortality through various mechanisms. PM2.5 leads inflammation metabolic disruptions. Ozone CO induce stress vascular dysfunction. NO2 cardiac remodeling acute events, metals exacerbate cellular damage. Pesticides microplastics pose emerging risks linked tissue Monitoring risk assessment play a crucial role identifying vulnerable populations assessing pollutant impacts, considering factors age, gender, socioeconomic status, lifestyle disorders. This review explores disease, discussing risk-assessment methods, intervention strategies, challenges clinicians face addressing pollutant-induced diseases. It calls for stronger regulatory policies, public health interventions, green urban planning.
Language: Английский
Citations
3
European Journal of Preventive Cardiology, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 15, 2025
Abstract Aim Air pollution remains the single largest environmental health risk factor, while atrial fibrillation (AF) is most prevalent arrhythmia globally. The study aimed to investigate relationship between short-term exposure air and acute AF admissions. Methods Individual data on hospitalization in years 2011-2020 were collected from National Health Fund Poland (ICD-10: I48.XX). To obtain high-resolution we applied a modelling method using GEM-AQ model. Associations admissions estimated generalized additive models with Poisson regression. Results Over analysed period, recorded 252,566 due AF. Each 10 µg/m3 increment of PM2.5 NO2 concentration, 1 SO2 ng/m3 benzo(a)pyrene (BaP) concentration day resulted 1.13% (0.70%−1.55%), 1.65% (1.05%−2.26%), 0.11% (0.01%−0.21%), 0.3% (0.04%−0.55%) increases admissions, respectively. estimates are larger for women older people. Stronger associations BaP concentrations poorly urbanized areas noted. Areas high gross domestic product levels more affected by increase concentrations, resulting 0.2% (1.001-1.003) Exposure-response functions show steeper slopes pollutant-outcome lower ranges exposures, far below World Organization (WHO) quality guideline norms. For zero-emission scenario, estimate avoidable - 5,873 (95% CI 3,679 8,047) 3,295 (2,108-4,477). Conclusions acts as triggering factor can be associated hospitalisations. have an impact even at WHO
Language: Английский
Citations
1
European Heart Journal, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 24, 2024
Atrial fibrillation (AF) has become the pre-dominant arrhythmia worldwide and is associated with high morbidity mortality. Its pathogenesis intricately linked to deleterious impact of cardiovascular risk factors, emphasizing pivotal imperative for early detection mitigation strategies targeting these factors prevention primary AF. While traditional are well recognized, an increasing number novel have been identified in recent decades. This review explores emerging non-traditional AF, including unhealthy lifestyle current society (sleep, night shift work, diet), biomarkers (gut microbiota, hyperuricaemia, homocysteine), adverse conditions or diseases (depression, epilepsy, clonal haematopoiesis indeterminate potential, infections, asthma), environmental (acoustic pollution other factors). Unlike individuals limited control over many posing challenges conventional strategies. The purpose this outline evidence on associations new-onset AF potential mechanisms related factors. Furthermore, aims explore interventions at both individual societal levels mitigate growing burden suggesting guideline updates prevention.
Language: Английский
Citations
7
The American Journal of Medicine, Journal Year: 2024, Volume and Issue: 137(11), P. 1042 - 1048
Published: July 4, 2024
Language: Английский
Citations
1
Methodist DeBakey Cardiovascular Journal, Journal Year: 2024, Volume and Issue: 20(5), P. 111 - 123
Published: Jan. 1, 2024
The exposome encompasses the full range of environmental exposures throughout a person's lifetime and plays an important role in cardiovascular health. Interactions with social, natural, built components significantly impact disease prevalence mortality. Robust data analytics, including machine learning geospatial analysis, have advanced our understanding how these factors converge to influence risk. integration multiomics platforms computational approaches enhances ability characterize exposome, leading targeted public health interventions innovative risk reduction strategies aimed at improving globally. These that integrate such as genomics, epigenomics, clinical data, social factors, wearable technology will greater detail concerning In this review, we elucidate discuss recent literature regarding their relationship
Language: Английский
Citations
0
JACC Advances, Journal Year: 2024, Volume and Issue: 4(1), P. 101460 - 101460
Published: Dec. 13, 2024
Language: Английский
Citations
0