Financial conflicts of interest among authors of clinical practice guideline for headache disorders in Japan DOI Creative Commons
Anju Murayama, Yuki Senoo

BMC Medical Ethics, Journal Year: 2024, Volume and Issue: 25(1)

Published: Oct. 29, 2024

Financial relationships between clinical guideline authors and pharmaceutical companies introduce conflicts of interest (COI), potentially biasing recommendations. Thus, proper management COI is paramount for authors. Nevertheless, little known about among neurology This study aimed to evaluate the financial Clinical Practice Guideline Headache Disorders (CPGHD) in Japan. a retrospective analysis 2016–2020 personal payments data disclosed by all affiliated with Japan Pharmaceutical Manufacturers Association. We examined amounts fraction 57 CPGHD neurologists board-certified Japanese Society Neurology. Payment was descriptively analyzed at individual author level. Among authors, 56 (98.3%) received totaling $2.7 million from 2016 2020. Median five-year were $89,955 while $521 neurologists. The chairperson vice substantial during development period. because less rigorous transparent policy compared international standard policies, only 10 their guideline. More than 98% much higher those period

Language: Английский

Cross‐Sectional Analysis of Research and Non‐Research Payments From the Medical Device Industry to Healthcare Professionals and Organisations in Japan in 2022 DOI Creative Commons
Anju Murayama

Journal of Evaluation in Clinical Practice, Journal Year: 2025, Volume and Issue: 31(2)

Published: March 1, 2025

ABSTRACT Rationale Financial relationships between healthcare professionals (HCPs), organisations (HCOs) and the medical device industry in Japan may lead to conflicts of interest. Limited transparency these has raised concerns regarding their potential influence on clinical decision‐making patient care. Aims Objectives This study aimed assess scope magnitude financial payments from companies HCPs HCOs Japan, focusing publicly disclosed data 2022 fiscal year. Methods A cross‐sectional analysis available payment disclosures 169 companies, including all members Federation Medical Devices Associations (JFMDA) several major non‐JFMDA affiliated was conducted. Descriptive statistics were calculated summarise data. Results Of 32.5% (55 companies) did not disclose information 6 records aggregated amounts with group leaving 108 for analysis. In total, $245.2 million made 2022, only 23.9% ($58.7 million) research development. 34.6% ($84.9 allocated non‐research sponsoring HCOs’ activities, 19.6% ($49.0 paid lecturing consulting fees, typically individual HCPs. More than 80% a greater share activities research. Conclusion reveals substantial HCPs/HCOs predominantly purposes. Improved regulations, uniform, government‐run database, are necessary better oversee interactions Japan.

Language: Английский

Citations

0

Pharmaceutical company payments to Japanese breast cancer practice guideline authors DOI Creative Commons
Anju Murayama, Kenichi Higuchi, Keerthana R. Byreddy

et al.

Clinical and Translational Discovery, Journal Year: 2024, Volume and Issue: 4(3)

Published: June 1, 2024

Abstract Background The creation of breast cancer practice guidelines requires proper management financial relationships with drug companies, as they can introduce conflicts interest (COIs) among guideline authors. However, little is known about the specific landscape and fraction interactions between authors Japanese Breast Cancer Society Clinical Practice Guidelines for Cancer, edition 2022 (JBCS2022) companies. Methods Using payment data publicly disclosed by major companies in Japan, this study analysed personal payments made to JBCS2022 2016 2020. We performed descriptive analyses on data. Results Of 149 authors, 115 (77.2%) received at least one totaling $3 828 455 from average median amounts per author were $25 772 (standard deviation: $58 197) $2761 (interquartile range: $322‒$15 828), respectively. total annual 2019 increased $588 054 $967 802 2019. chairperson vice‐chairperson $246 936 (fourth highest) $216 744 (fifth over 5 years. More than 60% not declared below declaration threshold set Society. nine undeclared summing $594 615 even though these higher thresholds. Conclusion This demonstrated that majority Japan. Furthermore, because less transparent COI policy.

Language: Английский

Citations

3

Cross-sectional analysis of pharmaceutical industry payments to authors of clinical practice guidelines for bipolar disorder and major depressive disorder in Japan DOI Creative Commons
Anju Murayama, Hinari Kugo, Yuki Senoo

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(6), P. e086396 - e086396

Published: June 1, 2024

Objective Clinical practice guidelines (CPGs) are essential for standardising patient care based on evidence-based medicine. However, the presence of financial conflicts interest (COIs) among CPG authors can undermine their credibility. This study aimed to examine extent and size COIs psychiatry CPGs in Japan. Methods cross-sectional analysis disclosed payments from pharmaceutical companies assesses prevalence magnitude personal lecturing, consulting writing bipolar disorder major depressive Japan between 2016 2020. Results found that 93.3% received over a 5-year period, with total exceeding US$4 million. The median payment per author was US$51 403 (IQR: US$9982–US$111 567), notable concentration small number authors, including chairperson. Despite these extensive relationships, only fraction CPGs. These large amounts were made by manufacturing new antidepressants sleeping aids listed Conclusions more than 93% considerable industry. findings highlight deviations international COI management standards suggest need stringent policies

Language: Английский

Citations

1

Non-research payments to board-certified cardiologists from pharmaceutical industry in Japan from 2016 to 2019: a retrospective analysis DOI Creative Commons
Anju Murayama, Kenichi Higuchi, Yuki Senoo

et al.

BMJ Open, Journal Year: 2024, Volume and Issue: 14(7), P. e083445 - e083445

Published: July 1, 2024

Objectives To evaluate the extent and trends of personal payments from pharmaceutical companies to cardiologists board-certified by Japanese Circulation Society. Design A retrospective analysis study using data a publicly available database. Setting The focused on in Japan. Participants All 15 048 who were Society as 2021. Primary secondary outcome measures primary was 2016–19. Secondary outcomes included these over same period. Results Of all cardiologists, 9858 (65.5%) received totaling $112 934 503 entailing 165 013 transactions median payment per cardiologist $2947 (IQR, $1022–$8787), with mean $11 456 (SD, $35 876). Gini Index 0.840, indicating high concentration small number cardiologists. top 1%, 5% 10% 31.6%, 59.4% 73.5% payments, respectively. There no significant receiving or during Conclusions More than 65% 4-year Although amount relatively for majority vast payments.

Language: Английский

Citations

1

Pharmaceutical industry payments to authors of neurology clinical practice guidelines in Japan: A cross‐sectional study DOI Creative Commons
Anju Murayama, Yuki Senoo

Health Science Reports, Journal Year: 2024, Volume and Issue: 7(9)

Published: Sept. 1, 2024

Language: Английский

Citations

0

Financial conflicts of interest among authors of clinical practice guideline for headache disorders in Japan DOI Creative Commons
Anju Murayama, Yuki Senoo

BMC Medical Ethics, Journal Year: 2024, Volume and Issue: 25(1)

Published: Oct. 29, 2024

Financial relationships between clinical guideline authors and pharmaceutical companies introduce conflicts of interest (COI), potentially biasing recommendations. Thus, proper management COI is paramount for authors. Nevertheless, little known about among neurology This study aimed to evaluate the financial Clinical Practice Guideline Headache Disorders (CPGHD) in Japan. a retrospective analysis 2016–2020 personal payments data disclosed by all affiliated with Japan Pharmaceutical Manufacturers Association. We examined amounts fraction 57 CPGHD neurologists board-certified Japanese Society Neurology. Payment was descriptively analyzed at individual author level. Among authors, 56 (98.3%) received totaling $2.7 million from 2016 2020. Median five-year were $89,955 while $521 neurologists. The chairperson vice substantial during development period. because less rigorous transparent policy compared international standard policies, only 10 their guideline. More than 98% much higher those period

Language: Английский

Citations

0