BOLD fMRI responses to amplitude modulated sounds across age in adult listeners DOI Creative Commons
Søren A. Fuglsang, Jonatan Märcher‐Rørsted, Kristoffer H. Madsen

et al.

Imaging Neuroscience, Journal Year: 2024, Volume and Issue: 2, P. 1 - 14

Published: Jan. 1, 2024

Abstract Age-related alterations in the auditory system have been suggested to affect processing of temporal envelope amplitude modulations (AM) at different levels hierarchy, yet few studies used functional magnetic resonance imaging (fMRI) study this noninvasively humans with high spatial resolution. In study, we utilized sparse-sampling fMRI 3 Tesla (3T) investigate regional blood oxygenation level-dependent (BOLD) responses AM noise stimuli 65 individuals ranging age from 19 77 years. We contrasted BOLD modulated 4 Hz or 80 unmodulated stimuli. This allowed us derive measures neural sensitivity imposed AM. Compared noise, slowly varying elicited significantly greater left and right cortex along Heschl’s gyrus (HG). were than putatively primary cortical regions lateral HG. magnitude regions. find no discernible effects on recruitment by While results affirm involvement rate information, they provide support for age-related these measures. discuss potential caveats assessing changes pathway.

Language: Английский

BOLD fMRI responses to amplitude modulated sounds across age in adult listeners DOI Creative Commons
Søren A. Fuglsang, Jonatan Märcher‐Rørsted, Kristoffer H. Madsen

et al.

Imaging Neuroscience, Journal Year: 2024, Volume and Issue: 2, P. 1 - 14

Published: Jan. 1, 2024

Abstract Age-related alterations in the auditory system have been suggested to affect processing of temporal envelope amplitude modulations (AM) at different levels hierarchy, yet few studies used functional magnetic resonance imaging (fMRI) study this noninvasively humans with high spatial resolution. In study, we utilized sparse-sampling fMRI 3 Tesla (3T) investigate regional blood oxygenation level-dependent (BOLD) responses AM noise stimuli 65 individuals ranging age from 19 77 years. We contrasted BOLD modulated 4 Hz or 80 unmodulated stimuli. This allowed us derive measures neural sensitivity imposed AM. Compared noise, slowly varying elicited significantly greater left and right cortex along Heschl’s gyrus (HG). were than putatively primary cortical regions lateral HG. magnitude regions. find no discernible effects on recruitment by While results affirm involvement rate information, they provide support for age-related these measures. discuss potential caveats assessing changes pathway.

Language: Английский

Citations

1