Diverging neural dynamics for syntactic structure building in naturalistic speaking and listening

Proceedings of the National Academy of Sciences, Journal Year: 2024, Volume and Issue: 121(11)

Published: March 5, 2024

The neural correlates of sentence production are typically studied using task paradigms that differ considerably from the experience speaking outside an experimental setting. In this fMRI study, we aimed to gain a better understanding syntactic processing in spontaneous versus naturalistic comprehension three regions interest (BA44, BA45, and left posterior middle temporal gyrus). A group participants (n = 16) was asked speak about events episode TV series scanner. Another 36) listened spoken recall participant first group. To model processing, extracted word-by-word metrics phrase-structure building with top–down bottom–up parser make different hypotheses timing structure building. While anticipates structure, sometimes before it is obvious listener, builds integratory way after all evidence has been presented. comprehension, activity found be modeled by parser, while production, parser. We additionally two strategies were developed here predictions incrementality during speaking. for highly incremental anticipatory which confirmed converging analysis pausing patterns speech. Overall, study shows feasibility studying dynamics language production.

Language: Английский

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Lesion-symptom Mapping of Acceptability Judgments in Chronic Poststroke Aphasia Reveals the Neurobiological Underpinnings of Receptive Syntax

Journal of Cognitive Neuroscience, Journal Year: 2024, Volume and Issue: 36(6), P. 1141 - 1155

Published: Jan. 1, 2024

Abstract Disagreements persist regarding the neural basis of syntactic processing, which has been linked both to inferior frontal and posterior temporal regions brain. One focal point debate concerns role areas in receptive ability, is mostly assessed using sentence comprehension involving complex structures, a task that potentially confounded with working memory. Syntactic acceptability judgments may provide better measure syntax by reducing need use high memory load sentences enabling assessment various types violations. We therefore tested perception grammatical violations people poststroke aphasia (n = 25), along matched controls 16), English errors word order, agreement, or subcategorization. Lesion data were also collected. Control participants performed near ceiling accuracy higher discriminability agreement subcategorization than order; less able discriminate violations, but, on average, paralleled control Lesion-symptom mapping showed correlation between regions, but not regions. argue these results diverge from models holding are amodal core structure building favor posit hierarchical system

Language: Английский

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ROSE: A neurocomputational architecture for syntax

Journal of Neurolinguistics, Journal Year: 2023, Volume and Issue: 70, P. 101180 - 101180

Published: Nov. 21, 2023

Language: Английский

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The neurobiology of sentence production: A narrative review and meta-analysis

Brain and Language, Journal Year: 2025, Volume and Issue: 264, P. 105549 - 105549

Published: Feb. 20, 2025

Although there is a sizeable body of literature on sentence comprehension and processing both in healthy disordered language users, the production remains much more sparse. Linguistic computational descriptions expressive syntactic deficits aphasia are especially rare. In addition, neuroimaging (psycho) linguistic literatures operate largely separately. this paper, I will first lay out theoretical land with regard to psycholinguistic models production. then provide brief narrative overview large-scale meta-analysis as it pertains computation, followed by an attempt integrate findings from functional clinical neuroimaging. Finally, surrounding propose path forward close some existing gaps.

Language: Английский

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Common and distinct patterns underlying different linguistic tasks: multivariate disconnectome symptom mapping in poststroke patients

Cerebral Cortex, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 23, 2024

Abstract Numerous studies have been devoted to neural mechanisms of a variety linguistic tasks (e.g. speech comprehension and production). To date, however, whether how the patterns underlying different are similar or differ remains elusive. In this study, we compared 3 mainly concerning production. address this, multivariate regression approaches with lesion/disconnection symptom mapping were applied data from 216 stroke patients damage left hemisphere. The results showed that could predict both poststroke scores production tasks; these exhibited shared regions on temporal pole hemisphere as well unique contributing prediction for each domain. Lower in associated lesions/abnormalities superior gyrus middle gyrus, while lower inferior parietal lobe frontal lobe. These suggested an important role ventral dorsal stream pathways (i.e. supporting dual model) highlighted applicability novel disconnectome-based cognitive neuroscience research.

Language: Английский

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Mapping sentence comprehension and syntactic complexity: evidence from 131 stroke survivors

Brain Communications, Journal Year: 2024, Volume and Issue: 6(6)

Published: Jan. 1, 2024

Abstract Understanding and interpreting how words are organized in a sentence to convey distinct meanings is cornerstone of human communication. The neural underpinnings this ability, known as syntactic comprehension, far from agreed upon current neurocognitive models language comprehension. Traditionally, left frontal regions (e.g. posterior inferior gyrus) were considered critical, while more recently, temporal (most prominently, middle have been identified indispensable Syntactic processing has investigated by using different types non-canonical sentences i.e. those that do not follow prototypical word order syntactically complex. However, can be complex for linguistic reasons, thus, their comprehension might rely on underpinnings. In cross-sectional study, we explored the correlates investigating roles hemisphere brain white matter pathways with levels complexity. Participants assessed at single point time structural MRI behavioural tests. Employing lesion–symptom mapping indirect disconnection cohort 131 stroke survivors, our analysis revealed following underlying crucial general comprehension: mid-posterior superior gyrus, gyrus sulcus longitudinal fasciculus, fronto-occipital uncinate fasciculus tracts crossing most part corpus callosum. We further found significant involvement connecting lobes types. Spared connections between critical requiring long-distance retrieval (spared both subject object extraction spared arcuate extraction) but passive canonical declarative sentences. Our results challenge traditional emphasize primary role regions, such Broca’s area, basic structure findings suggest gradient complexity, rather than clear-cut dichotomy structures. contribute nuanced understanding architecture highlight potential directions future research.

Language: Английский

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Verbal short term memory contribution to sentence comprehension decreases with increasing syntactic complexity in people with aphasia

NeuroImage, Journal Year: 2024, Volume and Issue: 297, P. 120730 - 120730

Published: July 14, 2024

Sentence comprehension requires the integration of linguistic units presented in a temporal sequence based on non-linear underlying syntactic structure. While it is uncontroversial that storage mandatory for this process, there are opposing views regarding relevance general short-term-/working-memory capacities (STM/WM) versus language specific resources. Here we report results from 43 participants with an acquired brain lesion extended left hemispheric network and resulting deficits, who performed sentence-to-picture matching task experimental assessing phonological short-term memory. The sentence systematically varied complexity (embedding depth argument order) while lengths, number propositions plausibility were kept constant. Clinical data including digit-/ block-spans size site additionally used analyses. Correlational analyses confirm performance STM/WM-tasks (experimental digit-span) only two relevant predictors correct sentence-picture-matching, reaction times depended age size. Notably increasing reduced correlational strength speaking additional recruitment resources independent more verbal STM/WM capacities, when resolving complex complementary lesion-behaviour analysis yielded different volumes correlating either sentence-task or STM-task. Factoring out STM measures lesions anterior lobe correlated larger decrease accuracy complexity. We conclude overall depends capacity, increases tax another cognitive resource.

Language: Английский

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Verbal working memory and syntactic comprehension segregate into the dorsal and ventral streams, respectively

Brain Communications, Journal Year: 2024, Volume and Issue: 6(6)

Published: Jan. 1, 2024

Abstract Syntactic processing and verbal working memory are both essential components to sentence comprehension. Nonetheless, the separability of these systems in brain remains unclear. To address this issue, we performed causal-inference analyses based on lesion connectome network mapping using MRI behavioural testing two groups individuals with chronic post-stroke aphasia. We employed a rhyme judgement task heavy load without articulatory confounds, controlling for overall ability match auditory words pictures perform metalinguistic judgement, isolating effect (103 individuals). assessed non-canonical comprehension, syntactic by incorporating residual performance as covariate (78 Voxel-based structural connectome-based symptom total volume were performed, permutation correct multiple comparisons (4000 permutations). observed that effects localized dorsal stream damage: posterior temporal-parietal lesions frontal-parietal white matter disconnections. These differentiated from comprehension deficits, which primarily associated ventral temporal lobe disconnections, particularly when measure covariate. Our results support conclusion distinct networks, largely loading onto streams, respectively.

Language: Английский

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Verbal working memory and syntactic comprehension segregate into the dorsal and ventral streams

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: May 5, 2024

Abstract Syntactic processing and verbal working memory are both essential components to sentence comprehension. Nonetheless, the separability of these systems in brain remains unclear. To address this issue, we performed causal-inference analyses based on lesion connectome network mapping using MRI behavioral testing 103 individuals with chronic post-stroke aphasia. We employed a rhyme judgment task heavy load without articulatory confounds, controlling for overall ability match auditory words pictures perform metalinguistic judgment, isolating effect load. assessed noncanonical comprehension, syntactic by incorporating residual performance as covariate Voxel-based structural connectome-based symptom total volume were performed, permutation correct multiple comparisons (4,000 permutations). observed that effects localized dorsal stream damage: posterior temporal-parietal lesions frontal-parietal white matter disconnections. These differentiated from comprehension deficits, which primarily associated ventral temporal lobe disconnections, particularly when measure covariate. Our results support conclusion distinct networks, largely loading onto streams, respectively.

Language: Английский

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Effects of low-frequency rTMS combined with speech and language therapy on Broca’s aphasia in subacute stroke patients

Frontiers in Neurology, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 30, 2024

Broca's aphasia is a crushing syndrome after stroke. Although there are multiple therapies, the recovery of considerable number patients still not ideal. Repetitive transcranial magnetic stimulation (rTMS) combined with speech and language therapy has been promising combination regimen in recent years. However, efficacy persistent effects thereof remain unclear. We aimed to determine immediate long-term rTMS on subacute stroke explore relevant mechanisms picture-naming task via functional near-infrared spectroscopy (fNIRS).

Language: Английский

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