Understanding Sleep and Circadian Disruption in the Intensive Care Unit DOI Creative Commons

Fernando G. Zampieri,

M. Elizabeth Wilcox

Annals of the American Thoracic Society, Journal Year: 2023, Volume and Issue: 20(11), P. 1558 - 1560

Published: Nov. 1, 2023

Language: Английский

Intensive care unit interventions to promote sleep and circadian biology in reducing incident delirium: a scoping review DOI
M. Elizabeth Wilcox, Lisa Burry, Marina Englesakis

et al.

Thorax, Journal Year: 2024, Volume and Issue: 79(10), P. 988 - 997

Published: Feb. 13, 2024

Despite plausible pathophysiological mechanisms, research is needed to confirm the relationship between sleep, circadian rhythm and delirium in patients admitted intensive care unit (ICU). The objective of this review summarise existing studies promoting, whole or part, normalisation sleep biology their impact on incidence, prevalence, duration and/or severity ICU.

Language: Английский

Citations

10

Nonpharmacological interventions to promote sleep in the adult critical patients unit: A scoping review DOI Creative Commons

Miguel Carrera,

Leyla Alegría, Pablo E. Brockmann

et al.

Australian Critical Care, Journal Year: 2025, Volume and Issue: 38(3), P. 101159 - 101159

Published: Jan. 16, 2025

Sleep and circadian rhythms are markedly altered in intensive care unit (ICU) patients. Numerous factors related to the patient ICU environment affect ability initiate maintain sleep. Therefore, nonpharmacological interventions could play an essential role improving sleep rhythm. The aim of this study was examine evaluated for promoting adult ICUs. A scoping review conducted, including randomised controlled trials, nonrandomised quasi-experimental other studies investigating effects total 57 articles 14 ongoing trials were included review, which 38 clinical trials. Nine improve critically ill patients evaluated: earplugs and/or eye masks, aromatherapy, bundles, music intervention, massage or acupressure, noise masking, bright light, dynamic light. Most simultaneously assessed effect more than one intervention on perceived quality using questionnaires. association between improved varied. In case multicomponent interventions, it is difficult identify components might have influenced improvement. various promote patients, several quality. However, substantial variability their implementation complicates drawing reliable conclusions. protocol registered with Open Science Framework under identifier https://doi.org/10.17605/OSF.IO/MPEQ5.

Language: Английский

Citations

0

Are ICU Bedspaces Based in Evidence, and Do They Support Patient Sleep? A Narrative Review DOI
Oystein Tronstad,

Irene Szollosi,

Dylan Flaws

et al.

HERD Health Environments Research & Design Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 2, 2025

Objective: This narrative review summarizes some of the evidence guiding current intensive care unit (ICU) design, focussing on environmental factors impacting sleep, and compares available recommendations to ICU designs builds. Background: The importance sleep for recovery after illness is well known. However, hospitalized patients frequently experience poor disrupted sleep. especially true admitted ICU. There are many negatively patients’ ability Some relate their or pre-existing problems; others patient activities. While bedspace may facilitate 24h care, there growing awareness detrimental impact environment (especially suboptimal lighting excessive sound/noise) has quality, important questions raised regarding how this health outcomes. Multiple guidelines exist guide design. have been whether contemporary ICUs evidence-based, effectively translated into built Methods: A comprehensive literature was conducted, exploring supporting design Results conclusion: outcomes describes features that not adhere best contribute Suggestions bedspaces can be improved optimize provided.

Language: Английский

Citations

0

Interaction between clock genes, melatonin and cardiovascular outcomes from ICU patients DOI Creative Commons
José Manuel Jiménez‐Pastor, Ignacio Morales‐Cané, Francisco José Rodríguez-Cortés

et al.

Intensive Care Medicine Experimental, Journal Year: 2025, Volume and Issue: 13(1)

Published: Feb. 17, 2025

Abstract Background Circadian rhythms, driven by biological clocks, help organisms align their physiological functions with environmental changes, promoting homeostasis. The central clock in the suprachiasmatic nucleus coordinates peripheral clocks via neurohumoral feedback involving proteins like CLOCK, BMAL1, CRY 1/2, and PER 1–3. In ICU, these circadian processes often face disruptions from constant lighting, noise, irregular sleep–wake cycles, impairing sleep quality worsening stress responses. These can lead to adverse clinical effects, including higher cardiovascular complication rates. This study examines how ICU stays affect rhythm regulators association outcomes. Results Significant differences were identified melatonin levels expression of PER1, RORA, NR1D1 between ≤7 days >7 days. APACHE-II severity scale influenced PER2, CRY2, RORA. Nonlinear relationships observed melatonin, genes, heart rate, blood pressure (systolic diastolic). certain groups, molecular data showed correlations exceeding 90%. Conclusions findings highlight a robust disruption, as measured rhythms patients.

Language: Английский

Citations

0

Sleep in the ICU – A complex challenge requiring multifactorial solutions DOI Creative Commons
Oystein Tronstad, John F. Fraser

Critical Care and Resuscitation, Journal Year: 2025, Volume and Issue: 27(1), P. 100097 - 100097

Published: Feb. 28, 2025

Language: Английский

Citations

0

Prospective cohort study on characteristics, associated factors and short-term prognosis of sleep and circadian rhythm in intensive care unit: protocol for the SYNC study DOI Creative Commons
Tingyu Guan, Jingjing Li, J. Hou

et al.

BMJ Open, Journal Year: 2025, Volume and Issue: 15(3), P. e091184 - e091184

Published: March 1, 2025

Acute sleep and circadian rhythm (SCR) disruption can lead to a range of negative physical mental consequences, such as depression, delirium, respiratory dysfunction increased mortality. In the intensive care unit (ICU), unique environment exacerbate disruptions in SCR. Few studies have identified characteristics SCR ICU, roles patient characteristics, illness medical interventions ICU remain unclear. A single-centre prospective cohort study, called SYNC study (Sleep rhYthm iNtensive Care unit), will be conducted explore associated factors investigate short-term prognosis among patients surgical ICU. Patients from at tertiary teaching hospital enrolled. assessed by both objective subjective indicators, including melatonin secretion rhythm, activity pattern perceived quality. Data on eight potential that influence SCR, light exposure, noise level, pain nighttime disturbances, mechanical ventilation, sedative analgesic use, meal restraints, collected. These data gathered first 3 days after admission. Short-term prognostic anxiety, cognitive function, insomnia, activities daily living, stay, stay mortality collected during 1 month discharge. The has been approved Ethics Committee Zhongshan Hospital, Fudan University (B2024-076R). results this published peer-reviewed journals. NCT06346613.

Language: Английский

Citations

0

Factors influencing sleep disturbances in patients staying in general departments DOI Creative Commons
Hana Locihová,

Sabina Psennerová,

K Axmann

et al.

Central European Journal of Nursing and Midwifery, Journal Year: 2025, Volume and Issue: 16(1), P. 2119 - 2126

Published: March 5, 2025

Aim: The main objective was to determine how hospitalized patients subjectively perceive sleep disturbances. study also assessed the influence of selected factors (physiological, physical, environmental, and psychological) clinical demographic variables on disruption. Design: A multicenter descriptive study. Methods: Conducted in seven Czech hospitals from February May 2023, included 397 general wards. Data were collected using a modified questionnaire disturbances, results analyzed non-parametric statistical tests. Results: sample comprised 193 males (48.6 %) 204 females (51.4%). Females reported more disturbances than (p = 0.023). Psychological physical had greater impact females. Younger poorer quality 0.015). Pain strongest factor that negatively affected (Ra 0.730). Environmental leading cause disturbance 0.836). variability associated with all studied (environmental, psychological, physiological, physical) accounted for 97.6% total disturbance. Conclusion: younger experienced environmental primary causes disrupted sleep. Differences noted affecting between genders.

Language: Английский

Citations

0

Delir: verstehen, vermeiden und behandeln DOI
Elisa Weidner,

Laura Hancke,

Peter Nydahl

et al.

neuroreha, Journal Year: 2025, Volume and Issue: 17(01), P. 31 - 43

Published: March 1, 2025

Citations

0

Sleep and Circadian-Related Outcomes after Critical Illness DOI
Margaret A. Pisani

Seminars in Respiratory and Critical Care Medicine, Journal Year: 2025, Volume and Issue: unknown

Published: March 31, 2025

Abstract Sleep and circadian disruptions are frequently reported in studies of critically ill patients. Less is known about sleep after an intensive care unit (ICU) admission. It recognized now that survivors critical illness may develop what termed post-intensive syndrome (PICS) which a constellation symptoms two the most prominent features fatigue complaints. Clinicians researchers recognizing importance examining impact their quality life. Although current data limited this review addresses post-ICU. Current ongoing research future should continue to inform our understanding how ICU environment both influence long-term outcomes

Language: Английский

Citations

0

Validation and the psychometric properties of the Persian version of the sleep quality scale for coronary care patients: a methodological survey DOI Creative Commons
Alireza Mirzaei, Leili Valizadeh,

Reza Imashi

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: April 21, 2025

Sleep quality is crucial for recovery in coronary care patients, yet sleep disturbances are prevalent intensive settings. This study aimed to validate the Persian version of Quality Scale Coronary Care Patients (SQ-CC-P) Iranian population and ensure its psychometric robustness clinical research applications. A methodological was conducted Unit (CCU) heart unit Imam Khomeini Hospital Ardabil Province, Iran, from May September 2024, involving 220 participants diagnosed with acute conditions. The SQ-CC-P, which includes self-assessment environmental factors, assessed content validity, construct reliability accordance COSMIN guidelines. SQ-CC-P demonstrated strong CVI (0.80-0.92), CVR (0.70-1.00), S-CVI/UA (0.85), S-CVI/Ave (0.91), Adjusted Kappa (0.697) confirming item relevance necessity. Construct validity supported by exploratory factor analysis (EFA), revealed a two-factor structure explaining 62.4% variance, confirmatory (CFA), showed loadings (0.72-0.82) excellent model fit. scale exhibited high internal consistency (Cronbach's alpha = 0.862, McDonald's omega 0.864) test-retest (ICC 0.785, 95% CI [0.718, 0.841]). valid reliable tool assessing among addressing critical gap assessment

Language: Английский

Citations

0