The effect of transient increase in intraocular pressure on subfoveal choroidal thickness

Optometry and Vision Science, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 13, 2024

SIGNIFICANCE Myopia prevalence has increased over the last few decades. Studies have documented that choroid is considered an important biomarker in myopia development. As and choroidal thinning are associated with glaucoma risk, understanding role of imperative. PURPOSE This study investigates effect transiently elevated intraocular pressure on axial length, subfoveal thickness, central retinal thickness emmetropes, low myopes, high myopes. METHODS involved 29 young adults (23 ± 1 years), including 10 emmetropes (−0.50 D < SE +0.50 D), myopes (−6.00 ≤ −0.50 9 (SE −6.00 D). Participants were fitted modified swimming goggles for 5 minutes to change pressure. Noncontact tonometry, optical biometry, coherence tomography used measure pressure, respectively. Measurements taken at before, during goggle wear, immediately after, 3 after removal. Repeated-measures analysis variance Bonferroni adjustment was assess changed elucidate any differences between refractive groups response change. RESULTS Intraocular by 1.7 2.1 mmHg (p=0.002) from baseline, accompanied elongation 14 21 μm (p = 0.012) 13 15 (p=0.01). However, did not significantly (p>0.05). Most changes length due thickness. Observed returned baseline following There no significant difference error groups' transient increase CONCLUSIONS Transiently caused temporary thinning, groups. Further studies required impact long-term ocular components.

Language: Английский

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Spontaneously Myopic Guinea Pig: Model of Early Pathologic Myopia

Investigative Ophthalmology & Visual Science, Journal Year: 2023, Volume and Issue: 64(14), P. 19 - 19

Published: Nov. 14, 2023

To evaluate whether pigmented guinea pigs with spontaneous myopia present characteristic changes of pathologic myopia.The fundus images (3 weeks old) were graded according to tessellation (FT) degree. Biometric parameters, including refraction, vitreous chamber depth (VCD), and axial length (AL), measured at ages 21 43 days. Some these animals divided into three groups: hyperopic without FT (H w/o FT), myopic (M w/ FT). The horizontal vertical radii curvature posterior sclera (RP-H RP-V, respectively) the arc lengths superior (RS LS, respectively), inferior (RI LI, nasal (RN LN, temporal (RT LT) evaluated by Fuji.The fundi as type A or B (both C (mild D (severe prevalence was correlated longer VCD, AL. Eyes M w/FT had shorter RP-H RS RT, LS LT than eyes H animals. Refractions shifted toward hyperopia in lacking FT, but not having FT. VCD consistent refraction. This relatively shift refraction shortening found only FT.Spontaneously pig have a high Myopic presented signs myopia.

Language: Английский

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Objective Measures of Gaze Behaviors and the Visual Environment during Near-Work Tasks in Young Adult Myopes and Emmetropes

Translational Vision Science & Technology, Journal Year: 2023, Volume and Issue: 12(11), P. 18 - 18

Published: Nov. 14, 2023

To objectively quantify near-work gaze behaviors and the visual environment during reading tasks performed on a smartphone paper in both indoor outdoor environments myopes emmetropes.

Language: Английский

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