Air-pulse optical coherence elastography: how excitation angle affects mechanical wave propagation DOI Creative Commons
Pengfei Song, Chengjin Song, Yubao Zhang

et al.

Biomedical Optics Express, Journal Year: 2025, Volume and Issue: 16(4), P. 1371 - 1371

Published: March 4, 2025

We evaluate the effect of excitation angles on observation and characterization surface wave propagations used to derive tissue’s mechanical properties in optical coherence tomography (OCT)-based elastography (OCE). Air-pulse stimulation was performed at center sample with ranging from oblique (e.g., 70° or 45°) perpendicular (0°). OCT scanning conducted radially record en face 360°, features (amplitude, attenuation, group phase velocities) were calculated spatiotemporal wavenumber-frequency domains. measurements isotropic, homogeneous samples (1–1.6% agar phantoms), anisotropic (chicken breast), complex boundaries, coupling media, stress conditions ( ex vivo porcine cornea, intraocular pressure (IOP): 5–20 mmHg). Our findings indicate that velocities are less affected by compared displacement features, demonstrating robustness using waves for elasticity estimations. Agar chicken breast showed all these metrics (particularly relatively consistent when smaller than 45°. However, significant disparities observed cornea across different (even between 15° 0°), particularly high IOP levels 20 provide valuable insights enhancing accuracy biomechanical assessments air-pulse-based other dynamic OCE approaches. This facilitates refinement clinical translation technique could ultimately improve diagnostic therapeutic applications various biomedical fields.

Language: Английский

Air-pulse optical coherence elastography: how excitation angle affects mechanical wave propagation DOI Creative Commons
Pengfei Song, Chengjin Song, Yubao Zhang

et al.

Biomedical Optics Express, Journal Year: 2025, Volume and Issue: 16(4), P. 1371 - 1371

Published: March 4, 2025

We evaluate the effect of excitation angles on observation and characterization surface wave propagations used to derive tissue’s mechanical properties in optical coherence tomography (OCT)-based elastography (OCE). Air-pulse stimulation was performed at center sample with ranging from oblique (e.g., 70° or 45°) perpendicular (0°). OCT scanning conducted radially record en face 360°, features (amplitude, attenuation, group phase velocities) were calculated spatiotemporal wavenumber-frequency domains. measurements isotropic, homogeneous samples (1–1.6% agar phantoms), anisotropic (chicken breast), complex boundaries, coupling media, stress conditions ( ex vivo porcine cornea, intraocular pressure (IOP): 5–20 mmHg). Our findings indicate that velocities are less affected by compared displacement features, demonstrating robustness using waves for elasticity estimations. Agar chicken breast showed all these metrics (particularly relatively consistent when smaller than 45°. However, significant disparities observed cornea across different (even between 15° 0°), particularly high IOP levels 20 provide valuable insights enhancing accuracy biomechanical assessments air-pulse-based other dynamic OCE approaches. This facilitates refinement clinical translation technique could ultimately improve diagnostic therapeutic applications various biomedical fields.

Language: Английский

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