Endoplasmic reticulum stress in gut inflammation: Implications for ulcerative colitis and Crohn’s disease DOI
Ting Zheng,

Kai-Yue Huang,

Xudong Tang

et al.

World Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: 31(13)

Published: April 2, 2025

Eukaryotic cells contain the endoplasmic reticulum (ER), a prevalent and intricate membranous structural system. During development of inflammatory bowel disease (IBD), stress on ER start unfolded protein response are very important. Some chemicals, including 4μ8C, small molecule agonists X-box binding 1, ISRIB, work inositol-requiring enzyme turn transcription factor 6, activate kinase RNA-like pathways. This may help ease symptoms IBD. Researchers investigating gut microbiota have discovered correlation between it. suggests that changing could make new medicines for study looks at how works it contributes to emergence It also talks about its possible clinical importance as therapeutic target into ways treat this condition.

Language: Английский

Endoplasmic reticulum stress in gut inflammation: Implications for ulcerative colitis and Crohn’s disease DOI
Ting Zheng,

Kai-Yue Huang,

Xudong Tang

et al.

World Journal of Gastroenterology, Journal Year: 2025, Volume and Issue: 31(13)

Published: April 2, 2025

Eukaryotic cells contain the endoplasmic reticulum (ER), a prevalent and intricate membranous structural system. During development of inflammatory bowel disease (IBD), stress on ER start unfolded protein response are very important. Some chemicals, including 4μ8C, small molecule agonists X-box binding 1, ISRIB, work inositol-requiring enzyme turn transcription factor 6, activate kinase RNA-like pathways. This may help ease symptoms IBD. Researchers investigating gut microbiota have discovered correlation between it. suggests that changing could make new medicines for study looks at how works it contributes to emergence It also talks about its possible clinical importance as therapeutic target into ways treat this condition.

Language: Английский

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