Frontiers in Human Neuroscience,
Journal Year:
2020,
Volume and Issue:
14
Published: April 7, 2020
Major
neurocognitive
changes
occur
during
adolescence,
making
this
phase
as
one
of
the
most
critical
developmental
period
life.
Furthermore,
in
life
is
also
time
youth
substance
use
has
its
onset.
Several
studies
demonstrated
differential
associations
alcohol
and
cannabis
concerning
functioning
both
males
females.
Past
contemporary
literature
on
gender-specific
effects
neuroscience
addiction
predominantly
based
cross-sectional
datasets
data
that
limited
terms
measurement
variability.
Given
importance
studies,
order
to
address
two
above-mentioned
gaps
literature,
present
study
aimed
compare
male
female
adolescents
context
use,
while
employing
a
longitudinal
design
with
multiple
repeated
measurements.
Participants
were
3,826
high
school
students
(47%
female;
mean
age,
12.7),
which
recruited
from
31
schools
greater
Montreal
area.
requested
complete
annual
surveys
for
five
consequent
years,
7th
11th
grade,
assessing
their
alcohol/cannabis
(working
memory,
delayed
recall
perceptual
reasoning,
inhibition
control).
The
analytical
strategy
was
focused
association
between
each
predictor
(female,
male)
outcomes
(domains
functioning).
Multilevel
linear
models
assessed
consumption
four
domains
functioning.
Results
revealed
gender
by
within-subject
interaction,
suggesting
weaker
effect
yearly
fluctuation
working
memory
among
compared
Our
findings
suggest
different
pattern
impairment
after
using
over
course
adolescence.
Early
initiation
potentially
results
more
spatial
deficits
adolescents.
This
may
negatively
influence
young
females’
capacity
academic
settings
lead
significant
adulthood,
critically
decreases
individual’s
quality
JAMA Psychiatry,
Journal Year:
2021,
Volume and Issue:
78(9), P. 1031 - 1031
Published: June 16, 2021
Animal
studies
have
shown
that
the
adolescent
brain
is
sensitive
to
disruptions
in
endocannabinoid
signaling,
resulting
altered
neurodevelopment
and
lasting
behavioral
effects.
However,
few
investigated
ties
between
cannabis
use
development
humans.
Frontiers in Human Neuroscience,
Journal Year:
2020,
Volume and Issue:
14
Published: Aug. 4, 2020
Adolescence
is
an
important
ontogenetic
period
that
characterized
by
behaviors
such
as
enhanced
novelty-seeking,
impulsivity,
and
reward
preference,
which
can
give
rise
to
increased
risk
for
substance
use.
While
use
rates
in
adolescence
are
generally
on
a
decline,
the
current
combined
with
emerging
trends,
increases
e-cigarette
use,
remain
significant
public
health
concern.
In
this
review,
we
focus
neurobiological
divergences
associated
adolescent
derived
from
cross-sectional,
retrospective,
longitudinal
studies,
highlight
how
of
these
substances
during
may
relate
behavioral
neuroimaging-based
outcomes.
Identifying
understanding
associations
between
changes
cognition,
mental
health,
future
assist
our
consequences
drug
exposure
critical
window.
Philosophical Transactions of the Royal Society B Biological Sciences,
Journal Year:
2018,
Volume and Issue:
374(1766), P. 20180137 - 20180137
Published: Dec. 31, 2018
Impulse
control
is
becoming
a
critical
survival
skill
for
the
twenty-first
century.
Impulsivity
implicated
in
virtually
all
externalizing
behaviours
and
disorders,
figures
prominently
aetiology
long-term
sequelae
of
substance
use
disorders
(SUDs).
Despite
its
robust
clinical
predictive
validity,
study
impulsivity
complicated
by
multidimensional
nature,
characterized
variety
trait-like
personality
dimensions,
as
well
more
state-dependent
neurocognitive
with
variable
convergence
across
measures.
This
review
provides
hierarchical
framework
linking
self-report
measures
to
latent
constructs
and,
turn,
different
psychopathology
vulnerabilities,
including
substance-specific
addictions
comorbidities.
dimensions
are
presented
novel
behavioural
targets
prevention
intervention.
Novel
treatment
approaches
addressing
domains
reviewed
recommendations
future
directions
research
interventions
SUDs
offered.
article
part
theme
issue
‘Risk
taking
impulsive
behaviour:
fundamental
discoveries,
theoretical
perspectives
implications’.
American Journal of Psychiatry,
Journal Year:
2022,
Volume and Issue:
179(5), P. 362 - 374
Published: March 8, 2022
Cannabis
use
is
increasing
among
midlife
and
older
adults.
This
study
tested
the
hypotheses
that
long-term
cannabis
associated
with
cognitive
deficits
smaller
hippocampal
volume
in
midlife,
which
important
because
are
risk
factors
for
dementia.
Annual Review of Developmental Psychology,
Journal Year:
2020,
Volume and Issue:
2(1), P. 461 - 483
Published: Oct. 13, 2020
This
review
summarizes
evidence
on
the
effects
of
cannabis
use
development
adolescents
and
young
adults.
It
draws
epidemiological
studies,
neuroimaging
case-control
twin
Mendelian
randomization
studies.
The
acute
risks
include
psychiatric
symptoms
associated
with
high
THC
(tetrahydrocannabinol)
products
motor
vehicle
accidents.
Daily
during
adolescence
is
dependence
poor
cognitive
function,
which
may
affect
educational
attainment
occupational
choice.
highly
potent
more
severe
psychological
symptoms,
such
as
psychoses,
mania,
suicidality.
There
are
mixed
findings
depressive
anxiety,
violence
debates
about
interpretation
these
associations.
Legalization
adult
increase
among
regulation
after
legalization
needs
to
minimize
adolescent
uptake
cannabis-related
adverse
developmental
outcomes.
Frontiers in Psychiatry,
Journal Year:
2021,
Volume and Issue:
12
Published: June 10, 2021
In
recent
years,
several
jurisdictions
have
revised
their
regulation
policy
toward
both
medical
and
recreational
use
of
cannabis.
These
changes
elicited
concerns
regarding
how
legalization
impacts
academic
achievement
work
performance.
This
review
evaluates
the
acute
long-term
(residual)
association
between
cannabis
cognitive
functioning
that
underlies
poor
Relative
to
other
reviews,
this
article
focuses
on
cross-over
randomized
controlled
trials
prospective
designs
given
they
allow
test
impairing
effects
exposure
at
within-subject
level.
Acute
are
discussed
separately
for
known
confounding
factors
such
as
levels
delta-9-tetrahydrocannabinol
(Δ9-THC),
Δ9-THC:cannabidiol
ratio,
previous
and,
comorbidity
with
psychosis-spectrum
disorders.
The
residual
detailed
in
relation
duration
abstinence,
frequency
use,
disorders,
types
domains
assessed,
age
initiation.
Moreover,
considering
fact
adequate
longitudinal
studies
can
make
inferences
about
causality
impaired
when
disentangling
between-subject
from
variation,
proofs
three
main
non-mutually
exclusive
hypotheses
relationship
will
be
presented:
i)
vulnerability
hypothesis
part
more
general
common
antecedent
hypothesis,
ii)
concurrent
iii)
neurotoxic
Current
research
provides
evidence
mild
moderate
episodic
working
memory,
processing
speed,
executive
functions.
Mild
were
also
observed
these
exact
same
domains,
suggesting
adverse
following
intoxication
persist
least
days
or
weeks
abstinence.
adult-onset,
adolescent-onset
seems
explain
dose-response
is
associated
longer
lasting
even
users
(
