A Computed Tomography-Based Score to Predict Survival in Patients With Adrenocortical Carcinoma: A Proof-of-Concept Study DOI
Maxime Barat, Mohamed Eltaher, Ahmed W. Moawad

et al.

Canadian Association of Radiologists Journal, Journal Year: 2025, Volume and Issue: unknown

Published: May 4, 2025

Purpose: Adrenocortical carcinoma (ACC) is a rare condition with poor and hardly predictable prognosis. This study aims to build evaluate preoperative computed tomography (CT)-based score (CT score) using features previously reported as biomarkers in ACC predict overall survival (OS) patients ACC. Methods: A CT based on examinations combining shape elongation, maximum tumour diameter, the European Network for Study of Adrenal Tumors (ENSAT) stage was built logistic regression model OS duration development cohort 89 An optimal cut-off defined Kaplan-Meier method used assess OS. The then tested an external validation 54 wit C-index predicting compared that ENSAT alone. Results: helped discriminate between prognosis good both (54 patients; mean OS, 69.4 months; 95% confidence interval [CI]: 57.4-81.4 months vs 75.6 CI: 62.9-88.4 months, respectively; P = .022). In significantly better than alone (0.62 0.35; .002). Conclusion: morphological criteria, radiomics, allows prognostic stratification

Language: Английский

CT Innovation in Pancreatic Imaging: A Bright Future, But Are We There Yet? DOI
Moran Drucker Iarovich, Maria Gladkikh, Christian B. van der Pol

et al.

Canadian Association of Radiologists Journal, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
A Computed Tomography-Based Score to Predict Survival in Patients With Adrenocortical Carcinoma: A Proof-of-Concept Study DOI
Maxime Barat, Mohamed Eltaher, Ahmed W. Moawad

et al.

Canadian Association of Radiologists Journal, Journal Year: 2025, Volume and Issue: unknown

Published: May 4, 2025

Purpose: Adrenocortical carcinoma (ACC) is a rare condition with poor and hardly predictable prognosis. This study aims to build evaluate preoperative computed tomography (CT)-based score (CT score) using features previously reported as biomarkers in ACC predict overall survival (OS) patients ACC. Methods: A CT based on examinations combining shape elongation, maximum tumour diameter, the European Network for Study of Adrenal Tumors (ENSAT) stage was built logistic regression model OS duration development cohort 89 An optimal cut-off defined Kaplan-Meier method used assess OS. The then tested an external validation 54 wit C-index predicting compared that ENSAT alone. Results: helped discriminate between prognosis good both (54 patients; mean OS, 69.4 months; 95% confidence interval [CI]: 57.4-81.4 months vs 75.6 CI: 62.9-88.4 months, respectively; P = .022). In significantly better than alone (0.62 0.35; .002). Conclusion: morphological criteria, radiomics, allows prognostic stratification

Language: Английский

Citations

0