Respiratory Medicine, Journal Year: 2025, Volume and Issue: 243, P. 108137 - 108137
Published: May 5, 2025
Language: Английский
Lipids in Health and Disease, Journal Year: 2025, Volume and Issue: 24(1)
Published: April 25, 2025
Preserved ratio impaired spirometry (PRISm) refers to a form of lung function deterioration, and previous studies have established the association with Chronic Obstructive Pulmonary Disease (COPD). Research has also shown between COPD lipid metabolism disturbances. Despite these findings, markers PRISm remains poorly understood. This analysis was conducted on 2007-2012 data from National Health Nutrition Examination Survey (NHANES), including total 9,431 participants. The Non-High-Density Lipoprotein Cholesterol High-Density Ratio (NHHR) calculated based profiles, patients were classified according pulmonary tests. To explore NHHR PRISm, multivariable logistic regression used. A strong linear observed PRISm. In Adjusted Model 2, weighted revealed that each unit increase in increased chance developing by 8% (OR:1.08, 95%CI:1.01-1.16, P = 0.039).Participants within highest tertile demonstrated 1.36-fold likelihood presenting compared those lowest (OR:1.36, 95% CI: 1.01-1.83, 0.048). Additionally, Restricted Cubic Spline affirmed (P for non-linearity 0.637), while clear non-linear associations found FEV1% predicted 0.010) FEV1/FVC 0.023). Subgroup interaction tests significant effect among different waist circumference categories 0.020). Notably, individuals without abdominal obesity, showed positive (OR 1.23, 1.07-1.42, 0.01). These results indicate is positively associated significantly decline function. study offers distinctive perspectives may contribute avoidance management early-stage dysfunction.
Language: Английский
Citations
0
Respiratory Medicine, Journal Year: 2025, Volume and Issue: 243, P. 108137 - 108137
Published: May 5, 2025
Language: Английский
Citations
0