European Respiratory Review,
Journal Year:
2024,
Volume and Issue:
33(172), P. 240057 - 240057
Published: April 10, 2024
Shareable
abstract
In
the
21st
century,
respiratory
health
delivery
continues
to
face
significant
challenges
in
context
of
climate
change,
plastic
pollution,
artificial
intelligence
and
continued
inequity.
Will
we
make
changes
time?https://bit.ly/3TS9jnO
Polymers,
Journal Year:
2024,
Volume and Issue:
16(19), P. 2807 - 2807
Published: Oct. 3, 2024
The
extensive
use
of
polymeric
materials
has
resulted
in
significant
environmental
pollution,
prompting
the
need
for
a
deeper
understanding
their
degradation
processes
and
impacts.
This
review
provides
comprehensive
analysis
environment
impact
on
health
experimental
animals.
It
identifies
common
polymers,
delineates
pathways,
describes
resulting
products
under
different
conditions.
covers
physical,
chemical,
biological
mechanisms,
highlighting
complex
interplay
factors
influencing
these
processes.
Furthermore,
it
examines
implications
products,
using
animals
as
proxies
assessing
potential
risks
to
human
health.
By
synthesizing
current
research,
focuses
studies
related
small
organisms
(primarily
rodents
invertebrates,
supplemented
by
fish
mollusks)
explore
effects
polymer
living
underscores
urgency
developing
implementing
effective
waste
management
strategies.
These
strategies
are
crucial
mitigating
adverse
impacts
degradation,
thus
promoting
more
sustainable
interaction
between
activities
natural
environment.
Small,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 16, 2025
Abstract
The
field
of
immunotherapeutics
is
rapidly
evolving
with
the
advent
cell
therapies,
complex
biologics,
and
a
host
other
compounds.
Polymeric
carriers
are
often
used
to
tune
safety
efficacy
profiles
these
novel
drugs.
Despite
their
prevalence
in
pre‐clinical
clinical
applications,
non‐degradable
materials
present
delivery
challenges
including
diffusion‐limited
release,
frustrated
phagocytosis,
limited
clearance.
In
contrast,
biodegradable
polymeric
systems
provide
safer
alternative
addition
displaying
advantageous
properties
for
immunotherapies.
this
review,
discussion
polymers
poly(lactic‐co‐glycolic
acid)
(PLGA),
poly(beta‐amino
esters)
(PBAEs),
acetalated
dextran
(Ace‐DEX),
chitosan,
alginate,
hyaluronic
acid
(HA)
as
immunomodulatory
biomaterial
suggest
that
variety
can
be
generate
tailored
formulations
different
therapeutic
payloads
disease
indications.
These
carrier
enhance
immunotherapies
via
tunable
degradation
rates,
enhanced
antigen‐presentation,
inherent
biomaterials,
among
mechanisms.
Polymers
formulated
applications
synthetic,
semi‐synthetic,
or
naturally
derived.
Therefore,
it
crucial
consider
environmental
impact
polymer
sources,
particle
fabrication
methods,
solvent
usage
sustainably
develop
effective
therapies
field.
Environmental Research,
Journal Year:
2025,
Volume and Issue:
unknown, P. 121278 - 121278
Published: March 1, 2025
Because
of
the
ubiquity
microplastics
(MPs)
in
environment
there
are
concerns
regarding
human
exposure.
In
this
study,
MPs
have
been
determined
three
physiological
fluids:
urine,
sputum
and
bronchoalveolar
fluid
(BALF);
from
30
adult
patients
Iran
with
respiratory
conditions.
A
total
nine
small
(20
-
100
μm)
mainly
green
red
fibres
polyethylene,
polypropylene
polystyrene
construction
were
detected
urine
samples
eight
participants.
By
contrast,
358
that
dominated
by
small,
white
transparent
fibres,
but
also
included
larger
(100
500
fragments
spherules,
samples.
Here,
a
broader
range
polymers
was
identified
polyurethane
dominant.
BALF
samples,
123
higher
proportion
along
spherules.
The
colour
distribution
these
similar
to
polymer
closer
These
observations
suggest
inhaled
ingested
might
be
fractionated
differently
though
body.
Further
research
is
required
elucidate
how
particles
than
theoretical
limits
(set
filtration
mechanisms)
present
fluids,
what
fractionation
processes
present,
whether
or
responsible
for
acute
chronic
health
impacts.
Israel Journal of Health Policy Research,
Journal Year:
2024,
Volume and Issue:
13(1)
Published: Sept. 10, 2024
Abstract
Background
Israel
is
a
regional
"hotspot"
of
plastic
pollution,
with
little
discussion
potential
adverse
health
effects
from
exposure
to
plastic.
This
review
aims
stimulate
and
drive
policy
by
focusing
on
these
effects.
Main
body
Plastics
are
synthetic
polymers
containing
additives
which
can
leach
food-
beverage-contact
into
our
food
beverages,
textiles
onto
skin.
persist
in
the
environment
for
generations,
fragmenting
MNPs:
Micro
(1
micron–5
mm)-Nano
nm–1
micron)-Plastic,
contaminate
atmosphere,
water,
chain.
MNP
enter
human
through
ingestion,
inhalation
touch.
<
10
microns
cross
epithelial
barriers
respiratory
gastrointestinal
systems,
fragments
100
nm
intact
skin,
enabling
entry
tissues.
have
been
found
multiple
organs
body.
Patients
atheromas
carotid
arteries
increased
risk
combined
measure
stroke,
cardiovascular
disease,
death.
Toxic
plastics
include
bisphenols,
phthalates,
PFAS,
endocrine-disrupting
chemicals
(EDCs)
cause
dysregulation
thyroid
function,
reproduction,
metabolism,
including
obesity,
diabetes,
endometriosis,
cancer,
decreased
fertility,
sperm
count
quality.
Fetal
EDCs
associated
rates
miscarriages,
prematurity
low
birth
weight.
There
likely
no
safe
level
EDCs,
increasing
evidence
trans-generational
epigenetic
several
existing
Israeli
laws
reduce
use
waste.
Taxes
single-use
(SUP)
were
recently
cancelled.
many
gaps
regulatory
standards
food-,
beverage-
child-
Existing
poorly
enforced.
Conclusion
Reduction
production
plastic,
promotion
recycling
reduction
leaching
toxic
beverages
essential
goals.
Specific
recommendations:
Periodic
monitoring
bottled
food,
indoor
air;
Strengthen
enforcement
beverage-,
child-safe
plastic;
Renew
tax
SUPs;
National
ban
SUP
at
public
beaches,
nature
reserves
parks;
Ban
products
manufactured
MNP;
Increase
research
sources
outcomes
EDCs.
Journal of Applied Ecology,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 11, 2025
Abstract
Microplastics
(MPs),
as
an
environmental
contaminant,
pose
a
significant
risk
to
both
animal
and
human
health
through
the
food
water
supply
chains.
Honey,
widely
recognised
safe
health‐oriented
product,
may
become
compromised
if
its
production
process
involves
non‐biodegradable
MPs.
This
study
was
conducted
systematic
review,
using
comprehensive
searches
of
PubMed,
Scopus
ScienceDirect
investigate
effects
MP
on
honey
bee
health,
potential
route
main
species
composition
contamination
in
honey.
review
highlights
impacts
MPs
including
mortality,
sucrose
response,
habituation,
olfactory
learning,
memory
recall,
colony
performance,
body
size
growth,
gut
microbiota
viral
infection.
From
mechanistic
perspective,
can
disrupt
equilibrium
microbiota,
adversely
impact
function
immune
system,
undermine
neural
signalling
pathways
that
are
critical
for
learning
processes
bees.
It
is
crucial
consider
applied
aspects
these
findings
beekeeping
practices,
adopting
sustainable
practices
mitigate
exposure
minimize
production.
The
also
provided
detailed
information
contact
routes
with
MPs,
environment
(air,
water,
soil,
pollen),
(plastic
hive
activities).
affect
by
altering
energy
homeostasis,
causing
oxidative
stress,
system
deficiencies,
malnutrition,
reduced
growth
decreased
reproductive
rates.
Synthesis
applications
.
this
highly
relevant
industry
public
policymakers.
By
identifying
key
detrimental
microplastics
(MPs)
quality,
research
provides
actionable
insights
beekeepers
adopt
management
minimise
exposure.
Additionally,
underscores
need
regulatory
policies
control
pollution,
ensuring
safety
product
protecting
pollinators
health.
