Cu-Mn Nanocomposite for Enhanced Tumor Cuproptosis achieved by Remodeling the Tumor Microenvironment and Activating the Antitumor Immunogenic Responses

Acta Biomaterialia, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Harnessing nano-delivery systems to un-cover the challenges for cervical cancer therapy

International Journal of Pharmaceutics, Journal Year: 2025, Volume and Issue: 677, P. 125657 - 125657

Published: April 28, 2025

Language: Английский

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Photoresponse performance of Au (nanocluster and nanoparticle) TiO2: Photosynthesis, characterization and mechanism studies

Results in Chemistry, Journal Year: 2024, Volume and Issue: 10, P. 101731 - 101731

Published: Aug. 1, 2024

Language: Английский

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(Nano)biotechnological approaches in the treatment of cervical cancer: integration of engineering and biology

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 13, 2024

Cervical cancer is one of the most malignant gynaecological tumors characterised with aggressive behaviour tumor cells. In spite development different strategies for treatment cervical cancer, cells have developed resistance to conventional therapeutics. On other hand, nanoparticles been recently applied human cancers through delivery drugs and facilitate suppression. The stimuli-sensitive nanostructures can improve release therapeutics at site. present review, are discussed. Nanostructures deliver both chemotherapy natural compounds increase anti-cancer activity prevent drug in tumor. Moreover, genetic tools such as siRNA be delivered by enhance their accumulation order selectivity, stimuli-responsive pH- redox-responsive nanocarriers suppress induce photo-thermal photodynamic therapy accelerate cell death addition, nanobiotechnology demonstrates tremendous potential especially context immunotherapy. Overall, metal-, carbon-, lipid- polymer-based utilized therapy. Finally, hydrogels novel kinds carriers encapsulate activity.

Language: Английский

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Self-Assembly MoS₂@MnO₂ Nanoflowers for the Fluorescence/Magnetic Resonance Dual-Modal Sensing of H₂O₂ and Photothermal Therapy

ACS Applied Nano Materials, Journal Year: 2023, Volume and Issue: 6(23), P. 22265 - 22274

Published: Nov. 21, 2023

The functions of bioimaging and photothermal therapy integrated into a theranostic nanosystem to prove its diagnostic therapeutic capabilities are desirable. versatile molybdenum disulfide (MoS2) dots doped with manganese dioxide (MnO2) nanoflowers (MoS2@MnO2 NFs) were designed for the dual-modal fluorescence/magnetic resonance (MR) sensing/imaging intracellular H2O2, as well thermal/MR imaging-guided in vivo. MnO2 nanosheets MoS2@MnO2 NFs acted an H2O2-mediated initiator, exhibiting fluorescence recovery Mn2+-related MR signal enhancement through specific H2O2-induced sheet degradation. Under optimal experimental conditions, fluorescence/MR sensor was used quantitatively detect image H2O2 limit detection (LOD) 0.09 μM. Simultaneously, thermal-responsive showed robust cytotoxicity toward cancer cells upon near-infrared (NIR) irradiation, allowing it serve drug This demonstrated power multimodal enhanced while reducing biotoxicity mice.

Language: Английский

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Medical nanoscale materials for virus-induced cervical cancer therapeutic modalities: For targeting delivery

OpenNano, Journal Year: 2024, Volume and Issue: 21, P. 100221 - 100221

Published: Nov. 18, 2024

Language: Английский

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