Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Journal of Hazardous Materials Letters, Journal Year: 2024, Volume and Issue: unknown, P. 100125 - 100125
Published: Sept. 1, 2024
Language: Английский
Citations
12
Nano-Structures & Nano-Objects, Journal Year: 2025, Volume and Issue: 41, P. 101437 - 101437
Published: Jan. 13, 2025
Language: Английский
Citations
0
Cancers, Journal Year: 2025, Volume and Issue: 17(5), P. 858 - 858
Published: March 2, 2025
The implementation of novel analytic methodologies in cancer and biomedical research has enabled the quantification parameters that were previously disregarded only a few decades ago. A notable example this paradigm shift is widespread integration atomic force microscopy (AFM) into laboratories, significantly advancing our understanding cell biology treatment response. AFM allows for meticulous monitoring different at molecular nanoscale levels, encompassing critical aspects such as morphology, roughness, adhesion, stiffness, elasticity. These can be systematically investigated correlation with specific treatment, providing important insights morpho-mechanical properties during normal treated conditions. resolution system holds potential its systematic adoption clinics; application could produce useful diagnostic information regarding aggressiveness efficacy treatment. This review endeavors to analyze current literature, underscoring pivotal role research, especially cases, while also contemplating prospective clinical context.
Language: Английский
Citations
0
European Journal of Cell Biology, Journal Year: 2025, Volume and Issue: unknown, P. 151492 - 151492
Published: April 1, 2025
Holotomograhic microscopy (HTM) has emerged as a non-invasive imaging technique that offers high-resolution, quantitative 3D of biological samples. This study explores the application HTM in examining endothelial cells (ECs). overcomes limitations traditional methods capturing real-time dynamics ECs by leveraging refractive index (RI) to map distributions label-free. work demonstrates utility visualizing key cellular processes during endothelialization, wherein anchor, adhere, migrate, and proliferate. Leveraging high resolution power HTM, we show lipid droplets mitochondria are readily visualized, enabling more comprehensive studies on their respective roles endothelialization. The highlights how commercial instrument can uncover novel insights into HUVEC cell behavior, offering potential applications medical diagnostics research, particularly developing treatments for cardiovascular diseases. advanced not only enhances our understanding EC biology but also presents significant step forward diseases, providing robust platform future research therapeutic development.
Language: Английский
Citations
0
bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 6, 2024
Abstract Holotomograhic microscopy (HTM) has emerged as a non-invasive imaging technique that offers high-resolution, quantitative 3D of biological samples. This study explores the application HTM in examining endothelial cells (ECs). overcomes limitations traditional methods capturing real-time dynamics ECs by leveraging refractive index (RI) to map distributions label-free. work demonstrates utility visualizing key cellular processes during endothelialization, wherein anchor, adhere, migrate, and proliferate. Leveraging high resolution power HTM, we show lipid droplets mitochondria are readily visualized, enabling more comprehensive studies on their respective roles endothelialization. The highlights how can uncover novel insights into EC behavior, offering potential applications medical diagnostics research, particularly developing treatments for cardiovascular diseases. advanced not only enhances our understanding biology but also presents significant step forward diseases, providing robust platform future research therapeutic development.
Language: Английский
Citations
2
Semiconductors, Journal Year: 2024, Volume and Issue: 58(12), P. 1027 - 1048
Published: Dec. 1, 2024
Language: Английский
Citations
1
Frontiers in Marine Science, Journal Year: 2024, Volume and Issue: 11
Published: July 18, 2024
The rising problem of plastic pollution is becoming one the major environmental issues for world. In ocean, plastics undergo degradation into smaller microplastics (MPs) and nanoplastics (NPs). Wild fish farmed salmon would likely be exposed to these NPs MPs both through skin wounds. Keratocyte cells, located in epithelial layer, are scavenger cells which may remove foreign materials maintain salmon’s health. They therefore first line handle suffer from MP NP exposure. While impacts have been well studied many different organisms, much less known about effects exposure, particularly at subcellular level. Here, we used holotomographic fluorescence microscopy show that corneal keratocyte fully internalize 500–1000 nm polystyrene particles, as inorganic 500 silica particles. fact also take up particles novel. Furthermore, some end lysosomal compartments within 2 hours conventional new modalities a role play understand how micro- nano affect cells.
Language: Английский
Citations
0
Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Citations
0