Proteomics in Diagnostic Evaluation and Treatment of Breast Cancer: A Scoping Review DOI Open Access
Μenelaos Zafrakas, Ioannis Gavalas,

Panayiota Papasozomenou

et al.

Journal of Personalized Medicine, Journal Year: 2025, Volume and Issue: 15(5), P. 177 - 177

Published: April 27, 2025

Objectives: The aim of this scoping review was to delineate the current role and possible applications proteomics in personalized breast cancer diagnostic evaluation treatment. Methods: A comprehensive search PubMed/MEDLINE Scopus/EMBASE conducted, according PRISMA–ScR guidelines. Inclusion criteria: proteomic studies specimens from patients, clinically relevant clinical studies. Exclusion silico, vitro animal models, articles, case reports, series, comments, editorials, articles language other than English. study protocol registered Open Science Framework. Results: In total, 1093 records were identified, 170 papers retrieved 140 selected for data extraction. Data analysis synthesis evidence showed that most analyses conducted tumor (n = 77), followed by blood samples 48), less frequently biologic material taken patients 19). commonly used methods liquid chromatography–tandem mass spectrometry (LC–MS/MS), Matrix-assisted laser desorption/ionization-time flight (MALDI–TOF), Surface-Enhanced Laser Desorption/Ionization Time-of-Flight (SELDI–TOF) Reverse Phase Protein Arrays (RPPA). Conclusions: present provides a thorough map published literature reporting results yielded various biological different subgroups patients. This shows that, although are not currently everyday practice guide decision-making, nevertheless numerous proteins identified could be as biomarkers treatment

Language: Английский

The application trends of proteomics in breast cancer: A bibliometric and visualization study over the past decade DOI Creative Commons
Binjun He, Hongfeng Chen

Asian Journal of Surgery, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Proteomics in Diagnostic Evaluation and Treatment of Breast Cancer: A Scoping Review DOI Open Access
Μenelaos Zafrakas, Ioannis Gavalas,

Panayiota Papasozomenou

et al.

Journal of Personalized Medicine, Journal Year: 2025, Volume and Issue: 15(5), P. 177 - 177

Published: April 27, 2025

Objectives: The aim of this scoping review was to delineate the current role and possible applications proteomics in personalized breast cancer diagnostic evaluation treatment. Methods: A comprehensive search PubMed/MEDLINE Scopus/EMBASE conducted, according PRISMA–ScR guidelines. Inclusion criteria: proteomic studies specimens from patients, clinically relevant clinical studies. Exclusion silico, vitro animal models, articles, case reports, series, comments, editorials, articles language other than English. study protocol registered Open Science Framework. Results: In total, 1093 records were identified, 170 papers retrieved 140 selected for data extraction. Data analysis synthesis evidence showed that most analyses conducted tumor (n = 77), followed by blood samples 48), less frequently biologic material taken patients 19). commonly used methods liquid chromatography–tandem mass spectrometry (LC–MS/MS), Matrix-assisted laser desorption/ionization-time flight (MALDI–TOF), Surface-Enhanced Laser Desorption/Ionization Time-of-Flight (SELDI–TOF) Reverse Phase Protein Arrays (RPPA). Conclusions: present provides a thorough map published literature reporting results yielded various biological different subgroups patients. This shows that, although are not currently everyday practice guide decision-making, nevertheless numerous proteins identified could be as biomarkers treatment

Language: Английский

Citations

0