Bibliometric analysis of the usage of tenecteplase for stroke

International Journal of Emergency Medicine, Journal Year: 2024, Volume and Issue: 17(1)

Published: Nov. 1, 2024

In recent years, tenecteplase has been competing with alteplase as a treatment for acute ischemic stroke given its ease of administration, lower dosage, cost-effectiveness, and better safety data. This paper seeks to analyze academic literature regarding the burgeoning usage across world. The Web Science database was used collect data from articles containing keywords "Tenecteplase" "Stroke" published 1999 2023. search resulted in 576 journal articles. study analyzed metadata related country, institution, keywords, date each article pertaining use stroke. United States led publications (260, 39.93%), followed by Australia (101, 15.51%), tie third place between Canada China (77, 11.83% each). three most prevalent were (N = 324), 284), thrombolysis 244). University Melbourne Calgary leading institutions publishing on 2023, number greatest, making up 24.3% all papers topic. surge 2023 could be good indicator drug's increasing prevalence Despite this finding, is currently not an FDA-approved therapy US Genentech, manufacturer, yet file federal approval treatment.

Language: Английский

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Enhancing Quadruple Health Outcomes after Thoracic Surgery: A Feasibility Pilot Randomized Controlled Trial Utilizing Digital Home Monitoring. (Preprint)

Published: April 5, 2024

Surgical recovery after hospital discharge often presents challenges for patients and caregivers. Postoperative complications poorly managed pain at home can lead to unexpected visits the emergency department and/or readmission hospital. Digital monitoring (DHM) may improve postoperative care compared standard methods. We conducted a feasibility study randomized controlled trial (RCT) assess DHM's effectiveness following thoracic surgical procedures care. two-arm parallel-group pilot RCT single tertiary center. Adult undergoing were 1:1 into two groups: digital (DHM group) of (control group). adhered intention-to-treat analysis principle. The primary outcome was predetermined criteria. would be feasible if more than 75% recruitment, protocol adherence, data collection achieved. Secondary outcomes included 30-day visit rates, complications, length stay, post-discharge opioid consumption, quality (QOR-40), patient/program satisfaction, caregiver healthcare provider satisfaction cost-per-case. All criteria met. recruitment rate 87.9% (95% CI: 79.4% – 93.8%). Protocol adherence rates 96.3% 89.4% - 99.2%) 98.7% 92.9% 99.9%), respectively. Eighty randomized, with 40 (50%) in DHM group control group. Baseline patient clinical characteristics comparable between groups. had fewer unplanned ED (2.7% vs. 20.5%; p=.02), admission (0% 7.6%; p=.24), lower (20% 47.5%, p=.01) shorter stays (4.0 6.9 days; p=.05), but consumption (111.6 ± 110.9 74.3 71.9 mg morphine equivalents; p=.08) also resulted times (130 0 1048 + 1093 minutes; p=.48) cost per case ($12,145 8,779 $17,247 15,313; p=.07). scores clinically significantly better controls (185.4 2.6 178.3 3.3; p<.0001). 37 who completed intervention answered program survey questionnaires (100%; 95% 90.5% 100%). Only 36 out 80 caregivers responded end 4th week post-hospital (47.7%; 35.7% 59.1%). Healthcare providers reported 100% rate. This demonstrates conducting full-scale efficacy improving surgery. shows promise enhancing continuity warrants further investigation. registered ClinicalTrials.gov (NCT04340960)

Language: Английский

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Inconsistently Accurate: Repeatability of GPT-3.5 and GPT-4 in Answering Radiology Board–style Multiple Choice Questions

Radiology, Journal Year: 2024, Volume and Issue: 311(2)

Published: May 1, 2024

Language: Английский

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Analysis of the political viewpoint of policy statements from professional medical organizations using ChatGPT 4.0 (Preprint)

Published: Sept. 6, 2024

Professional medical organizations publish policy statements that are used to impact legislation or address societal issues. Many nonpartisan, yet it is uncertain whether their balance liberal and conservative values. We determined the political viewpoint (liberal vs conservative) of from six organizations: American Academy Pediatrics (AAP), College Surgeons (ACS), Psychiatric Association (APA), Obstetricians Gynecologists (ACOG), Physicians (ACP), Family (AAFP). To evaluate alignment influential including: AAP, ACS, APA, ACOG, ACP, AAFP. Between 12/2023 – 2/2024, were identified evaluated using ChatGPT 4.0, remove bias. Each statement was pasted into a new session following phrase, “Does this text align with viewpoint?” Two authors reviewed each response categorized as: liberal; probably (PL); neutral; (PC); conservative. One third found be aligned ideology (529/1592). Among these, 516 (98%) PL 13 (2%) PC. For organization, among leaning, percentage was: 100% AAP; ACOG; ACS; 99% APA; 97% AAFP; 96% ACP. in three these professional politically partisan. positions 40-times more likely than Whether not neutral seek diversity warrants further exploration.

Language: Английский

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Bibliometric analysis of ChatGPT and plastic surgery research: Insights from diverse search strategies and co-word analysis

Chinese Journal of Plastic and Reconstructive Surgery, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

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