Efficacy of Intraoperative Paracetamol and Nefopam Infusions in Addition to Transversus Abdominis Plane Block in Kidney Transplant Recipients

Medicina, Journal Year: 2025, Volume and Issue: 61(1), P. 65 - 65

Published: Jan. 2, 2025

Background and Objectives: Kidney transplantation (KT) is an important treatment modality for renal failure. However, moderate-to-severe pain often occurs in KT recipients. Multimodal analgesia using combined analgesic measures has been recommended to enhance postoperative recovery. This retrospective study explored the additional efficacy of paracetamol nefopam infusions living-donor recipients who received a transversus abdominis plane (TAP) block. Materials Methods: Consecutive at our institute between January 2020 March 2022 were divided into groups that TAP block with (Group TA) or without analgesics T) during surgery. Following propensity-score (PS) matching, 103 patients included each group. Postoperative intensity assessed visual analog scale (VAS), opioid consumption via patient-controlled (PCA) devices over 24 h, outcomes compared two groups. Results: VAS rest was lower group TA than T 1 6 h after surgery [1 h: 29 (15–41) vs. 41 (29–51) mm, p < 0.001; 32 (23–43) 40 (32–54) 0.001]. The coughing 46 (30–58) 59 (48–69) 51 (40–63) 60 (45–71) Moreover, PCA consumptions first 6–24 post-surgery significantly TA. Other did not differ Conclusions: intraoperative improved control preoperative Our findings demonstrate

Language: Английский

Assessing the clinical advantage of opioid-reduced anesthesia in thoracoscopic sympathectomy: A prospective randomized controlled trial

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 9, 2024

Background: Opioid-reduced multimodal analgesia has been clinically used for years to reduce perioperative complications related opioid drugs. We aimed assess the clinical effects of opioid-reduced anesthesia during thoracoscopic sympathectomy. Methods: Surgical patients (n=151) with palmar hyperhidrosis were randomly divided into a control group (Group C, 73 patients) and weak W, 78 patients). All administered general using laryngeal mask. In Group anesthetized propofol, fentanyl, cisatracurium, mechanical ventilation was operation. received dezocine, dexmedetomidine (DEX), spontaneous breathing maintained surgery. Perioperative opioids include hypotension, bradycardia, hypertension, tachycardia, hypoxemia, nausea, vomiting, urine retention, itching, dizziness; vital signs, blood gas index, visual analog scale (VAS) score, other adverse events; patient satisfaction between groups also recorded. Results: similar groups. There no significant differences in type sedation, respiratory circulatory indicators, analysis, postoperative VAS scores, reactions, propofol dosage, recovery time, (P > 0.05). Conclusions: In minimally invasive surgeries such as sympathectomy, safe effective; however, this method did not show advantages. Trial registration Chinese Clinical Trial Register: ChiCTR2100055005, on December 30, 2021.

Language: Английский

Assessing the clinical advantage of opioid-reduced anesthesia in thoracoscopic sympathectomy: a prospective randomized controlled trial

BMC Anesthesiology, Journal Year: 2024, Volume and Issue: 24(1)

Published: Sept. 12, 2024

Language: Английский