Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis

BMC Medicine, Journal Year: 2025, Volume and Issue: 23(1)

Published: Feb. 6, 2025

Since its emergence in 2019, COVID-19 has continued to pose significant threats both the physical and mental health of global population, as well healthcare systems worldwide (Raman et al., Eur Heart J 43:1157–1172, 2022). Emerging evidence indicates that may lead post-acute syndrome (PACS) with cardiovascular implications, potentially driven by factors such ACE2 interaction viruses, systemic inflammation, endothelial dysfunction. However, there remains a limited amount research on manifestations PACS, which delay development optimal treatment strategies for affected patients. Therefore, it is crucial investigate prevalence sequelae patients determine whether infection acts an independent risk factor these outcomes. This meta-analysis adhered PRISMA guidelines was registered PROSPERO (CRD42024524290). A systematic search PubMed, Embase, Cochrane Library conducted up March 17, 2024. The primary outcomes included hypertension, palpitations, chest pain, pooled effect estimate reported proportions odds ratios (ORs) 95% confidence intervals (CIs). Sensitivity subgroup analysis were performed assess robustness results identify sources heterogeneity. total 37 studies, encompassing 2,965,467 patients, analysis. Pooled from case–control studies revealed that, compared control group, ORs pain group 4.0 (95% CI: 1.6, 10.0). palpitation hypertension 3.4 1.1, 10.2) 1.7 1.8), respectively. PACS experiencing palpitation, 22% 14%, 33%), 18% 13%, 24%), 19% 12%, 31%), Our findings indicate 15% experience sequelae. Furthermore, significantly increases likelihood developing uninfected individuals. Future should prioritize investigating underlying pathological mechanisms targeted preventive management strategies. CRD42024524290.

Language: Английский

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Non-invasive blood glucose estimation using a novel white-box model: An interpretable machine learning approach

Biomedical Signal Processing and Control, Journal Year: 2025, Volume and Issue: 105, P. 107520 - 107520

Published: Feb. 5, 2025

Language: Английский

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Incidence and Risk Factors of New-onset Hypertension Up To 3 years Post SARS-CoV-2 Infection

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: March 11, 2025

COVID-19 can trigger new cardiovascular events, including hypertension, in the acute setting. However, few studies have reported sustained new-onset hypertension post-infection. Moreover, these a small sample size, inadequate controls, and short (< 1 year) follow-up time. This retrospective cohort study of 64,000 patients from Stony Brook Health System assessed incidence risk factors for after COVID-19. Contemporary COVID-negative controls were obtained propensity matched age, race, sex, ethnicity, major comorbidities before analyzing outcomes. The primary outcome was up to 3 years post index date. About 9.93% hospitalized 4.66% non-hospitalized developed Hospitalized COVID-positive more likely develop compared (HR = 1.57, 95%CI [1.35–1.81]) (HR: 1.42, [1.24–1.63]). Non-hospitalized not 1.05 [0.98–1.13]). one five greatest developing hypertension. These findings underscore are at increased well beyond phase disease. Close long-term follow-up, holistic workups, vigilant blood pressure screening and/or monitoring is needed.

Language: Английский

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Understanding the interplay between COVID-19 and diabetes: insights for the post-pandemic era

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: May 21, 2025

The global pandemic caused by the SARS-CoV-2 virus has had a profound impact on onset, progression, and management of diabetes, posing significant challenges to healthcare systems worldwide. This review elucidates multifaceted diabetes mellitus, emphasizing increased complexity glycemic in patients with infection following viral postpandemic era. In this study, we examined diverse effects individuals diabetes. These included an elevated risk morbidity, erratic fluctuations blood glucose levels, emergence complications associated related self-management disease. From mechanistic perspective, investigated factors: SARS-CoV-2-mediated direct damage islet beta cells, dysregulation RAAS system, impairment function oxidative stress, integrated stress response, reduced adiponectin levels insulin utilization efficiency metabolism. Furthermore, extend diabetic cardiovascular factors, such as coagulation abnormalities, hypertension, lipid results exacerbation development complications. highlights urgent need for refined strategies during later stages COVID-19. Additionally, there is mitigate COVID-19 long-term outcomes

Language: Английский

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