Understanding the medication regimens associated with anticholinergic burden in older people's mental health services in the UK DOI Creative Commons
Thomas R. E. Barnes, Delia Bishara, Alistair Burns

et al.

BJPsych Open, Journal Year: 2024, Volume and Issue: 10(5)

Published: Sept. 1, 2024

Background Medications with anticholinergic properties are associated a range of adverse effects that tend to be worse in older people. Aims To investigate medication regimens high burden, prescribed for adults under the care mental health services. Method Clinical audit prescribing practice, using standardised data collection tool. Results Fifty-seven trusts/healthcare organisations submitted on medicines 7915 patients: two-thirds (66%) were properties, while just quarter (23%) had regimen burden (total score ≥3 effect cognition (AEC) scale). Some 16% patients diagnosis dementia or mild cognitive impairment compared 35% those without such diagnoses. A was mostly because combinations commonly psychotropic medications, principally antidepressant and antipsychotic medications individual AEC scores 1 2. Conclusions Adults people's services multiple psychiatric physical disorders; these can have often an inadvertent consequence co-prescription modest activity. Prescribers should assess regimens, assiduously check consider alternative less where indicated. The use scale, as AEC, which identifies level central activity relevant helpful clinical guide.

Language: Английский

Investigation of the total anticholinergic load of reported anticholinergic drug-related adverse events using the Japanese adverse drug event report database: a retrospective pharmacovigilance study DOI Creative Commons

Yusuke Kan,

Maki Doi,

Yoshihiro Uesawa

et al.

Journal of Pharmaceutical Health Care and Sciences, Journal Year: 2025, Volume and Issue: 11(1)

Published: Jan. 30, 2025

Language: Английский

Citations

0
Understanding the medication regimens associated with anticholinergic burden in older people's mental health services in the UK DOI Creative Commons
Thomas R. E. Barnes, Delia Bishara, Alistair Burns

et al.

BJPsych Open, Journal Year: 2024, Volume and Issue: 10(5)

Published: Sept. 1, 2024

Background Medications with anticholinergic properties are associated a range of adverse effects that tend to be worse in older people. Aims To investigate medication regimens high burden, prescribed for adults under the care mental health services. Method Clinical audit prescribing practice, using standardised data collection tool. Results Fifty-seven trusts/healthcare organisations submitted on medicines 7915 patients: two-thirds (66%) were properties, while just quarter (23%) had regimen burden (total score ≥3 effect cognition (AEC) scale). Some 16% patients diagnosis dementia or mild cognitive impairment compared 35% those without such diagnoses. A was mostly because combinations commonly psychotropic medications, principally antidepressant and antipsychotic medications individual AEC scores 1 2. Conclusions Adults people's services multiple psychiatric physical disorders; these can have often an inadvertent consequence co-prescription modest activity. Prescribers should assess regimens, assiduously check consider alternative less where indicated. The use scale, as AEC, which identifies level central activity relevant helpful clinical guide.

Language: Английский

Citations

1