Polypharmacy Prevalence Among Older Adults Based on the Survey of Health, Ageing and Retirement in Europe: An Update

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(4), P. 1330 - 1330

Published: Feb. 17, 2025

Polypharmacy, a common condition among the older population, is associated with adverse outcomes, including higher mortality, falls and hospitalization rates, drug reactions, drug-drug interactions, medication nonadherence, consequently increased healthcare costs. Background/Objectives: This study aims to explore prevalence of polypharmacy its factors adults across 27 European countries Israel. Methods: In this cross-sectional analysis, we used data from participants aged 65 years or Wave 9 Survey Health, Aging, Retirement in Europe (SHARE) database. The variables studied were classified into following categories: sociodemographic, behavioral factors, physical functioning, health, mental living conditions. Results: Our results showed an overall 36.2%, ranging 25.0 51.8%. Slovenia, Greece, Switzerland lowest prevalence, whereas Portugal, Israel, Poland where was highest. Polypharmacy shown be all categories. Conclusions: highly prevalent population. Identification polypharmacy, such as those identified study, important identify monitor groups, which are most vulnerable polypharmacy. Interventions designed reduce should consider these associations.

Language: Английский

Frailty, polypharmacy, malnutrition, chronic conditions, and quality of life in the elderly: Large population-based study (Preprint)

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e50617 - e50617

Published: Aug. 15, 2024

Background Aging, a significant public health issue, is associated with multiple concurrent chronic diseases and aging-related conditions (geriatric syndromes). Objective This study aims to investigate the impact of age on geriatric syndromes intercorrelations between quality life (QoL) in older adults (aged ≥65 years) at population level. Methods A large representative sample was randomly selected from county China, Feidong, 17 towns 811,867 residents. Multiple conditions, (frailty, polypharmacy, malnutrition), QoL were assessed compared. Associations demographic information using multivariable-adjusted logistic regression. Intercorrelations age, syndromes, investigated both correlation analysis restricted cubic splines–based dose-response analysis. Results Older comprised 43.42% (3668/8447) entire population. The prevalence frailty, premalnutrition or malnutrition, impaired (median 73, IQR 69-78 years; 1871/3668, 51% men) 8.26% (303/3668), 15.59% (572/3668), 3.22% (118/3668), 10.8% (396/3668), respectively. Different sex subgroups mostly had similar (except that frailty occurred more often age). Premalnutrition malnutrition lower frequency obesity higher constipation, polypharmacy diabetes constipation hernia, hypertension, diabetes, physical disability, constipation. Mini Nutritional Assessment–Short Form, Groningen Frailty Indicator, EQ-5D-5L scores, as well number medications used, predicted each other QoL. Impaired polypharmacy. At 1.5-year follow-up, linked baseline, baseline. Causal mediation analyses showed mediated link worse Conclusions In this population-based adults, ≥1 syndromes. Geriatric intercorrelated with, predictive of, QoL; causal relationships existed QoL, being mediators. findings might be biased by residual confounding factors. It important perform personalized syndrome assessments stratified condition; active prevention intervention for, any help reduce others improve

Language: Английский

Exploring medication self-management in polypharmacy: a qualitative systematic review of patients and healthcare providers perspectives

Frontiers in Pharmacology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 13, 2024

Purpose: Polypharmacy presents many challenges to patient medication self-management. This study aims explore the self-management processes of in polypharmacy from perspectives both patients and healthcare providers, which can help identify barriers facilitators effective management. Methods: A systematic review qualitative studies was performed by searching seven databases: PubMed, Web Science, Cochrane Library, Embase, CINAHL, PsycINFO, MEDLINE, their establishment until August 2024. The Critical Appraisal Skills Programme (CASP) tool employed evaluate quality included. extracted data were then analysed thematically integrated into Taxonomy Everyday Self-management Strategies (TEDSS) framework. Results: total 16 included, involving 403 119 providers. Patient management measures mapped TEDSS framework, including categories such as medical management, support-oriented domains, emotional role Conclusion: Enhancing patients’ proactive health awareness, improving literacy, balancing lifestyle adjustments with therapy, dynamically reviewing optimizing medications, strengthening social support networks, helping integrate daily life are key elements that effectively assist self-managing medications. Future interventions improve ability should be designed for these issues. Systematic Review Registration: https://www.crd.york.ac.uk/PROSPERO/ , identifier CRD42024524742.

Language: Английский