Influence of Educational Films on Antiviral Prescription for COVID-19: Insights from Web-Based Survey in Japan

Antibiotics, Journal Year: 2025, Volume and Issue: 14(3), P. 276 - 276

Published: March 7, 2025

Background: Prescribing antiviral agents for severe acute respiratory syndrome coronavirus 2 requires careful consideration based on the patient’s risk factors disease progression and their vaccination status. However, effective interventions ensuring appropriate use of by physicians have yet to be fully established. Thus, this study evaluated impact an educational film prescription rates 2019 (COVID-19). Methods: This prospective, nationwide, web-based survey enrolled 1500 physicians. They were instructed view a short assess necessity prescribing in 16 fictitious scenarios featuring adult patients with COVID-19 varying statuses. We compared before after viewing film. Results: There was significant increase film, particularly nirmatrelvir/ritonavir prescribed cases involving immunocompromised (from 31.3% 49.4%) those obesity 15.1% 33.7%) who unvaccinated had no drug interactions. made little hypertension hyperlipidemia or underlying conditions. Conclusions: Short films may promote COVID-19. altering behavior appears limited varies according clinical context.

Language: Английский

Retrospective, Observational Analysis on the Impact of SARS-CoV-2 Variant Omicron in Hospitalized Immunocompromised Patients in a German Hospital Network—The VISAGE Study

Vaccines, Journal Year: 2024, Volume and Issue: 12(6), P. 634 - 634

Published: June 7, 2024

Aims: Endemic SARS-CoV-2 infections still burden the healthcare system and represent a considerable threat to vulnerable patient cohorts, in particular immunocompromised (IC) patients. This study aimed analyze in-hospital outcome of IC patients with severe infection Germany. Methods: retrospective, observational study, analyzed administrative data from inpatient cases (n = 146,324) 84 German Helios hospitals between 1 January 2022 31 December regard health care during first 12 months Omicron dominance. As primary objective, outcomes COVID-19-related acute respiratory (SARI) were by comparing 2037) without diagnoses 14,772). Secondary analyses conducted on SARI 129,515). A as composite endpoint was defined per WHO definition if one following criteria met: intensive unit (ICU) treatment, mechanical ventilation (MV), or death. Results: In total, 12% COVID-related patients, accounting for 15% ICU admissions, MV use, 16% deaths, resulting higher prevalence courses developing compared non-IC (Odds Ratio, OR 1.4, p < 0.001), based mortality (OR increased need treatment 1.3, 0.001) 1.2, 0.001). Among profoundly risk 4.0, Conclusions: Our findings highlight vulnerability COVID-19. The persistently high these era emphasizes necessity continuous assessment monitoring

Language: Английский

A Comparative Study of Clinical Characteristics and COVID-19 Vaccine Effectiveness Against SARS-CoV-2 Variants: Wild-Type, Alpha, Delta, and Omicron in Beijing, China

Infection and Drug Resistance, Journal Year: 2024, Volume and Issue: Volume 17, P. 5147 - 5161

Published: Nov. 1, 2024

To compare the clinical characteristics of symptoms and laboratory findings across SARS-CoV-2 variants (Wild-type, Alpha, Delta, Omicron) assess effectiveness COVID-19 vaccines in preventing abnormalities.

Language: Английский