BMC Surgery,
Journal Year:
2023,
Volume and Issue:
23(1)
Published: June 3, 2023
Abstract
Background
Multi-organ
dysfunction
syndrome
and
multi-organ
failure
are
the
leading
causes
of
late
death
in
patients
sustaining
severe
blunt
trauma.
So
far,
there
is
no
established
protocol
to
mitigate
these
sequelae.
This
study
assessed
effect
hemoperfusion
using
resin-hemoadsorption
330
(HA330)
cartridges
on
mortality
complications
such
as
acute
respiratory
distress
(ARDS)
systemic
inflammatory
response
(SIRS)
among
patients.
Methods
quasi-experimental
recruited
≥
15
years
age
with
trauma,
injury
severity
score
(ISS)
15,
or
initial
clinical
presentation
consistent
SIRS.
They
were
divided
into
two
groups:
Control
group
received
only
conventional
care,
while
case
adjunctive
hemoperfusion.
P-values
less
than
0.05
statistically
significant.
Results
Twenty-five
included
(Control
Case
13
12
patients).
The
presenting
vital
signs,
demographic
injury-related
features
(except
for
thoracic
severity)
similar
(p
>
0.05).
experienced
significantly
more
injuries
(Thoracic
AIS,
median
[IQR]:
3
[2–4]
vs.
2
[0–2],
p
=
0.01).
Eleven
twelve
had
ARDS
SIRS
before
hemoperfusion,
respectively,
decreased
considerably
after
Meanwhile,
frequency
did
not
decrease
group.
Hemoperfusion
reduced
rate
compared
(three
nine
patients,
0.027).
Conclusions
Adjunctive
an
HA330
cartridge
decreases
morbidity
improves
outcomes
suffering
from
Therapeutic Apheresis and Dialysis,
Journal Year:
2023,
Volume and Issue:
27(5), P. 890 - 897
Published: May 12, 2023
Abstract
Aim
To
evaluate
the
inflammatory
parameters
and
oxygenation
in
severe
coronavirus
disease‐19
patients
who
underwent
extracorporeal
cytokine
adsorption
(CA).
Methods
Patients
CA
for
storm
were
included
study.
The
changes
oxygenation,
laboratory
parameters,
mortality
rates
investigated.
Results
Thirty‐six
hemoglobin,
thrombocyte,
C‐reactive
protein
(CRP)
decreased,
PaO
2
/FiO
ratio
increased
(
p
<
0.001;
0.01;
=
0.04,
respectively).
Twelve
(33.3%)
received
a
single
session,
24
(66.6%)
or
more
sessions.
CRP
fibrinogen
levels
/FIO
session
group
0.04;
0.01,
In
multi‐session
group,
platelet,
procalcitonin,
0.02;
Day
15,
30,
90
61.1%,
83.3%,
88.9%.
Conclusion
with
hemoperfusion
reduced
improved
oxygenation;
however,
high.
International Journal of Nephrology,
Journal Year:
2022,
Volume and Issue:
2022, P. 1 - 8
Published: Jan. 6, 2022
Background.
There
is
very
little
published
data
on
outcomes
of
COVID-19
among
chronic
kidney
disease
(CKD)
patients.
We
compared
the
in
a
tertiary
care
renal
hospital
CKD
V
patients
hemodialysis
(HD),
peritoneal
dialysis
(PD),
and
initiation,
terms
duration
hospitalization,
in-patient
mortality,
30-day
mortality.
Methods.
A
total
436
patients,
either
HD,
PD,
or
with
who
were
admitted
at
National
Kidney
Transplant
Institute
(NKTI)
from
March
13,
2020,
to
August
31,
included.
Kaplan–Meier
survival
analysis
was
performed.
Comparison
probability
mortality
by
group
performed
using
Log-Rank
test.
values
≤0.05
considered
statistically
significant.
Results.
Among
298
(68%)
103
(24%)
35
(8%)
required
initiation.
Overall
in-hospital
34%;
38%
20%
37%
Total
27%;
32%
26%
16%
Median
follow-up
24
days.
137
deaths
recorded,
median
time
death
10
days;
8.5
days,
15.5
9
days
for
initiation
groups,
respectively.
Probability
significantly
higher
HD
versus
PD
(
id="M2">p<0.00001
)
id="M3">p=0.0234
).
Mortality
probability,
however,
not
different
id="M4">p=0.63
Conclusion.
diagnosed
NKTI,
those
had
PD.
Heliyon,
Journal Year:
2022,
Volume and Issue:
8(11), P. e11282 - e11282
Published: Oct. 26, 2022
There
is
no
definitive
treatment
for
COVID-19.
Hemoperfusion
and
plasmapheresis
have
only
been
studied
in
a
few
cases
of
In
this
study,
plasmapheresis-hemoperfusion
current
COVID-19
patients
were
compared
mortality.In
cross-sectional
103
with
underwent
hemoperfusion,
plasmapheresis,
conventional
medical
educational
hospitals
Ahvaz,
Iran.
A
census
method
was
used
to
include
the
study.
The
data
from
hospital
file
complete
checklist
containing
demographic
information,
clinical
findings,
paraclinical
findings
all
patients.There
not
statistically
significant
difference
(P-value
=
0.051)
between
group
(78.8%),
hemoperfusion
(71.9%),
(52.6%)
mortality
rates.
had
median
survival
time
18.9
days,
16.9
13.5
days.
terms
patient
time,
there
0.181).
Multiple
regression
results
showed
that
death
rates
(P
0.393)
0.073)
groups
different
those
group.As
result
differences
regard
or
times.
Asian Pacific Journal of Cancer Prevention,
Journal Year:
2022,
Volume and Issue:
23(11), P. 3735 - 3741
Published: Nov. 1, 2022
To
determine
the
occurrence
of
Activated
Leukocyte
Cell
Adhesion
Molecule
(ALCAM)
and
its
predictive
factors
in
patients
with
oral
squamous
cell
carcinoma
(OSCC).This
cross
sectional
study
was
concocted
on
102
OSCC
referred
to
Imam
Khomeini
Hospital
Tehran
during
1997-2015.
The
data
collection
tool
a
checklist
consisted
demographic
pathologic
(lymph
node
involvement,
differentiation,
tumor
size
location)
characteristics
which
extracted
from
patients'
medical
records.
evaluate
ALCAM,
new
sample
tissue
prepared
archive.
Finally,
multivariable
logistic
regression
model
used
ALCAM
by
STATA14.the
number
(%)
men
women
were
70
(68.6)
32
(31.4%),
respectively.
mean
age
(S.D)
participants
61.7
(15.6)
years.
Of
total
samples,
(38.2),
19
(18.6),
36
(35.3)
8
(7.8%)
samples
related
tongue,
mucosa,
skin
lips,
More
than
half
tumors
had
good
differentiation
lymph
involvement
74.5%
≥20
mm.
Also,
79.41%
positive
for
overall
incidence
ALCAM.
most
important
predictors
(OR:
3.46,
95%
CI:
1.71
-
7.01)
location
3,
1.03
8.72).
Similarly,
cytoplasmic
2.56,
1.38
4.76)
3.23,
1.08
9.64).
However,
only
predictor
membranous
0.36,
0.19
0.66).The
results
our
suggest
preliminary
evidence
potential
clinical
application
as
prognostic
biomarker
may
be
basis
future
application,
however
further
studies
are
recommended.
BMC Surgery,
Journal Year:
2023,
Volume and Issue:
23(1)
Published: June 3, 2023
Abstract
Background
Multi-organ
dysfunction
syndrome
and
multi-organ
failure
are
the
leading
causes
of
late
death
in
patients
sustaining
severe
blunt
trauma.
So
far,
there
is
no
established
protocol
to
mitigate
these
sequelae.
This
study
assessed
effect
hemoperfusion
using
resin-hemoadsorption
330
(HA330)
cartridges
on
mortality
complications
such
as
acute
respiratory
distress
(ARDS)
systemic
inflammatory
response
(SIRS)
among
patients.
Methods
quasi-experimental
recruited
≥
15
years
age
with
trauma,
injury
severity
score
(ISS)
15,
or
initial
clinical
presentation
consistent
SIRS.
They
were
divided
into
two
groups:
Control
group
received
only
conventional
care,
while
case
adjunctive
hemoperfusion.
P-values
less
than
0.05
statistically
significant.
Results
Twenty-five
included
(Control
Case
13
12
patients).
The
presenting
vital
signs,
demographic
injury-related
features
(except
for
thoracic
severity)
similar
(p
>
0.05).
experienced
significantly
more
injuries
(Thoracic
AIS,
median
[IQR]:
3
[2–4]
vs.
2
[0–2],
p
=
0.01).
Eleven
twelve
had
ARDS
SIRS
before
hemoperfusion,
respectively,
decreased
considerably
after
Meanwhile,
frequency
did
not
decrease
group.
Hemoperfusion
reduced
rate
compared
(three
nine
patients,
0.027).
Conclusions
Adjunctive
an
HA330
cartridge
decreases
morbidity
improves
outcomes
suffering
from
