Effectiveness of Transcranial Magnetic Stimulation on Executive Function, Attention, and Memory in Stroke Patients: A Systematic Review and Meta-Analysis DOI Open Access

Ha Thi Le,

Kenta Honma,

Hiroki Annaka

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 6, 2024

Transcranial magnetic stimulation (TMS) is an effective intervention for improving cognitive impairment in patients with stroke. However, its effectiveness the subdomains of cognition conflicting and not clearly established. This systematic review assessed efficacy TMS executive function, attention, memory this population. Seven databases, including PubMed, Scopus, Cochrane Library, Cumulated Index Nursing Allied Health Literature, NeuroBITE, Physiotherapy Evidence Database, OTseeker, were searched indexed literature until July 2024 to identify all randomized controlled trials (RCTs) effect stroke patients. was performed by Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines Handbook Library evaluated quality evidence using Risk Bias 2 tools grading recommendations assessment, development, evaluation (GRADE) systems. Meta-analyses standardized mean difference (SMD) (Hedge's g) as measure, subgroups explore potential outcomes. The research included 13 RCTs involving 496 results indicated that could affect function (six SMD = 0.55; 95% confidence interval, CI 0.04-1.05) (nine 0.57; 0.25-0.89) on attention (five 0.32; -0.1 0.75) clear. varied between very low according GRADE approach. In conclusion, may memory, but attention. outcomes from owing heterogeneity bias; therefore, should be considered caution, more rigorous needed.

Language: Английский

A Comprehensive Overview of the Current Status and Advancements in Various Treatment Strategies against Epilepsy DOI Creative Commons
Abdul Waris, Muhammad Siraj, Ayyaz Ali Khan

et al.

ACS Pharmacology & Translational Science, Journal Year: 2024, Volume and Issue: 7(12), P. 3729 - 3757

Published: Nov. 1, 2024

Epilepsy affects more than 70 million individuals of all ages worldwide and remains one the most severe chronic noncommunicable neurological diseases globally. Several neurotransmitters, membrane protein channels, receptors, enzymes, and, recently noted, various pathways, such as inflammatory mTORC complexes, play significant roles in initiation propagation seizures. Over past two decades, developments have been made diagnosis treatment epilepsy. Various pharmacological drugs with diverse mechanisms action other options developed to control seizures treat These include surgical treatment, nanomedicine, gene therapy, natural products, nervous stimulation, a ketogenic diet, gut microbiota, etc., which are developmental stages. Despite plethora options, one-third affected resistant current medications, while majority approved side effects, changes can occur, pharmacoresistance, effects on cognition, long-term problems, drug interactions, risks poor adherence, specific for certain psychological complications. Therefore, development new that no or minimal adverse is needed combat this deadly disease. In Review, we comprehensively summarize explain stages epilepsy well their status clinical trials advancements.

Language: Английский

Citations

2
METHODS OF MATHEMATICAL ANALYSIS AND PROCESSING OF EEG SIGNALS: OVERVIEW OF THE CURRENT STATE AND LATEST TRENDS DOI

Violeta A. Akhmedova,

Ganna R. Ovcharenko

Ukraïnsʹkij osvìtnʹo-naukovij medičnij prostìr., Journal Year: 2024, Volume and Issue: 1, P. 49 - 57

Published: July 16, 2024

Aim. With the help of retrospective analysis, establish current level achievements in field applying methods mathematical analysis and processing biomedical signals, particular EEG, characterize main trends. Materials methods. The research was conducted using theoretical methods, by studying analyzing freely available literature, publications, materials working groups domestic foreign scientists over past few years. Results. scientific works devoted to development EEG showed that five years there has been a deepening tendency separate improving hardware software parts electroencephalographic complexes. last them, turn, can be divided into several directions. first direction is improvement real-time including automatic included second combines signal detect existing pathologies predict onset pathological conditions, such as statistical, spectral-correlation building models. next brings together application for further use deep learning, convolutional neural networks epileptic seizures, sleep disorders, differentiation neuropsychiatric etc. prosthetics deserves special attention. Methods are widely implemented bionic prostheses. these directions considered detail work. Conclusions. While material technical part focused on issues recording biological finding optimal suppressing noise without losing useful does not currently have breakthrough results, already received developed rapidly. study neurophysiological basis cognitive processes, etc., always attracted interest scientists, but their implementation robotics developments given this new impetus.

Language: Английский

Citations

0
Repetitive transcranial magnetic stimulation for post-stroke epilepsy: a mini-review DOI Creative Commons
Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori

et al.

Acta Epileptologica, Journal Year: 2024, Volume and Issue: 6(1)

Published: Dec. 1, 2024

Abstract Post-stroke epilepsy (PSE) is a common complication of stroke, significantly impacting patient’s quality life. Repetitive transcranial magnetic stimulation (rTMS) an emerging potential non-invasive treatment for PSE. This review explores current evidence rTMS in PSE, highlighting its benefits and limitations. Initial studies suggested that may reduce the seizure burden. Some observed trend towards fewer seizures within two weeks initiation, indicating relatively rapid response. Additionally, be more effective when used combination with medication, particularly patients specific lesion locations (frontal/temporal lobes) types (complex partial seizures). points personalized protocols. However, has Studies often involve small sample sizes methodological variations, necessitating larger, well-designed trials standardized protocols to confirm efficacy safety Future research should also focus on optimization parameters, including frequency, duration, coil placement, course. Long-term are needed evaluate persistence effects control, cognitive function, overall patient outcomes. Refining selection criteria investigating underlying mechanisms therapeutic PSE crucial areas future exploration.

Language: Английский

Citations

0
Effectiveness of Transcranial Magnetic Stimulation on Executive Function, Attention, and Memory in Stroke Patients: A Systematic Review and Meta-Analysis DOI Open Access

Ha Thi Le,

Kenta Honma,

Hiroki Annaka

et al.

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 6, 2024

Transcranial magnetic stimulation (TMS) is an effective intervention for improving cognitive impairment in patients with stroke. However, its effectiveness the subdomains of cognition conflicting and not clearly established. This systematic review assessed efficacy TMS executive function, attention, memory this population. Seven databases, including PubMed, Scopus, Cochrane Library, Cumulated Index Nursing Allied Health Literature, NeuroBITE, Physiotherapy Evidence Database, OTseeker, were searched indexed literature until July 2024 to identify all randomized controlled trials (RCTs) effect stroke patients. was performed by Preferred Reporting Items Systematic Reviews Meta-Analyses guidelines Handbook Library evaluated quality evidence using Risk Bias 2 tools grading recommendations assessment, development, evaluation (GRADE) systems. Meta-analyses standardized mean difference (SMD) (Hedge's g) as measure, subgroups explore potential outcomes. The research included 13 RCTs involving 496 results indicated that could affect function (six SMD = 0.55; 95% confidence interval, CI 0.04-1.05) (nine 0.57; 0.25-0.89) on attention (five 0.32; -0.1 0.75) clear. varied between very low according GRADE approach. In conclusion, may memory, but attention. outcomes from owing heterogeneity bias; therefore, should be considered caution, more rigorous needed.

Language: Английский

Citations

0