Cancer Control, Journal Year: 2025, Volume and Issue: 32
Published: Feb. 1, 2025
Background Pancreatic cancer places a substantial global health and economic burden. However, the epidemiological characteristics chronological trends of pancreatic in high-income Asia-Pacific have not been systematically analyzed. Methods Data obtained from GBD 2021 database were used for this cross-country secondary analysis. We Joinpoint regression to analyze temporal disease burden Asia-Pacific. Age-period-cohort model was estimate describe impact age, period, cohort effects on outcomes. Bayesian age-period-cohort projection incidence 2022 2036. Results In Asia-Pacific, age-standardized prevalence rate (ASPR), mortality (ASMR), disability-adjusted life-years (DALYs) (ASDR) estimated be 11.2 (95% UI, 9.69-12.17), 9.56 8.34-10.34), 197.6 178.87-210.6) per 100 000 population, respectively, 2021, which all higher than those across Asia. From 1990 2002, rates (ASIRs) trend rather stable. Instead, ASIRs went up gradually 2002 2011 both males (APC = + 1.03, 95% CI: 0.85, 1.20) females 1.64, 1.40, 1.89). ASMRs considerably with increasing especially over 60. The region are predicted go down years ahead, approximately 12.81 11.11 2036 males, 8.97 8.42 females. Conclusion A comprehensive upward ASIRs, ASPRs, ASMRs, ASDRs observed between 2021. Given poor prognosis cancer, prevention strategies paramount, modifiable factors like smoking, alcohol drinking, obesity.
Language: Английский