Is Selective Laser Trabeculoplasty Effective in Reducing Intraocular Pressure for Primary Angle-Closure Glaucoma? A Systematic Review and Meta-Analysis

Current Eye Research, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: April 2, 2025

Primary angle-closure glaucoma (PACG) is a significant cause of blindness globally, particularly in Asian populations, where it accounts for 25% cases. Selective laser trabeculoplasty (SLT) has emerged as promising treatment PACG, but its efficacy varies across studies. This meta-analysis aims to evaluate the effectiveness SLT reducing intraocular pressure (IOP) and compare outcomes between PACG primary open-angle (POAG). A systematic search was conducted PubMed, Scopus, Medline, EMBASE up July 2024 using predefined criteria. Studies assessing patients with were included. Data extraction included study characteristics, parameters, outcomes, such mean post-intervention IOP reduction failure rates. Statistical analysis performed pooled estimates 95% confidence intervals (CI) through Comprehensive Meta-Analysis software. Of 754 potentially relevant articles assessed, 7 met inclusion The post-SLT among significantly decreased 17.30 mmHg (95% CI: 16.99-17.61; p = 0.0001). rate 7.95% 6.15-10.28%; 0.00001). reported varying trends medication use need further interventions patients. comprehensively examined treating multiple Despite variations sample sizes, demographics, locations, effectively reduced demonstrated statistically decrease IOP, highlighting therapeutic benefit despite notable heterogeneity

Language: Английский

Is Botulinum toxin A effective in treating dry eye disease? A systematic review and meta-analysis

Eye, Journal Year: 2025, Volume and Issue: unknown

Published: April 9, 2025

Language: Английский