Comparative Analysis of Influenza Epidemiology Before and After the COVID‐19 Pandemic in Argentina (2018–2019 vs. 2022–2023)
Influenza and Other Respiratory Viruses,
Journal Year:
2025,
Volume and Issue:
19(2)
Published: Feb. 1, 2025
ABSTRACT
Introduction
The
COVID‐19
pandemic
altered
the
epidemiology
of
respiratory
viruses
other
than
SARS‐CoV‐2.
This
study
investigated
clinical‐epidemiological
pattern
hospitalized
pediatric
patients
with
acute
lower
tract
infections
(ALRI)
and
influenza
in
Argentina,
comparing
prepandemic
postpandemic
periods.
Materials
Methods
multicenter,
cross‐sectional
included
under
18
years
old
admitted
for
ALRIs
five
tertiary
centers
Argentina
before
(2018
2019)
after
(2022
2023)
COVID‐19.
Changes
viral
detection
rates,
seasonality,
case
fatality
rate
(CFR),
along
epidemiological
clinical
characteristics,
were
analyzed.
Indirect
immunofluorescence
assay
(IFA)
or
RT‐PCR
was
used
virological
diagnosis
pre‐pandemic,
only
post‐pandemic.
Epi
Info
7
SPSS
15.0
data
analysis.
Results
A
total
5838
cases
ALRI
(mean
age:
9.5
months;
IQR:
4–22
months);
96.6%
tested
detection,
66.4%
positive
(3877
cases).
Respiratory
syncytial
virus
(RSV)
most
prevalent.
Influenza
showed
typical
winter
seasonality
2018,
2019,
2023.
However,
2022
exhibited
a
bimodal
pattern:
late
summer
spring,
co‐circulation
B
second
peak.
CFR
varied
by
diagnosis;
highest
CFR,
all
deaths
related
to
A.
Among
354
cases,
81%
<
5
old,
53%
male,
63%
had
comorbidities,
14.1%
required
intensive
care.
Mean
vaccine
coverage
(6–24
months)
21.4%.
In
both
periods,
more
likely
have
pneumonia.
Additionally,
period,
malnourishment
being
3
age
older
also
associated
higher
likelihood
infection
compared
viruses.
Conclusions
primarily
affected
children
old.
Postpandemic
involved
individuals,
increased
circulation
H3N2
observed.
Vaccination
notably
low.
returned
its
usual
seasonal
Language: Английский
Hals-Nasen- und Ohrenerkrankungen
Roland Seifert
No information about this author
Springer eBooks,
Journal Year:
2025,
Volume and Issue:
unknown, P. 669 - 677
Published: Jan. 1, 2025
Clinical characteristics of severe influenza as a risk factor for febrile seizures in children: a retrospective analysis
Frontiers in Pediatrics,
Journal Year:
2024,
Volume and Issue:
12
Published: Oct. 23, 2024
Objective
To
retrospectively
analyze
the
clinical
characteristics
and
independent
risk
factors
of
severe
influenza
combined
with
febrile
seizures,
to
provide
more
basis
for
early
intervention.
Methods
A
total
161
children
were
collected
as
study
subjects
divided
into
convulsive
(FC)
group
(40
cases)
non-convulsive
(NFC)
(121
according
whether
they
had
seizures.
The
demographic
data
two
groups
analyzed.
Multivariate
logistic
regression
was
used
predictive
efficacy
evaluated
by
receiver
operating
characteristic
(ROC)
curve
analysis.
Results
(1)
Multiple
analysis
revealed
that
C-reactive
protein
(CRP)
levels,
Serum
interleukin
6
(IL-6)
Days
from
onset
Flu
symptoms
hospitalization,
cerebrospinal
fluid
(CSF-TP)
levels
virus
type
(FluA)
infection
rate
found
be
seizures
in
children.
(2)
ROC
showed
cut-off
value
CRP,
IL-6,
hospitalization
CSF-TP
7.57
mg/L,
9.84
pg/ml,
4.5
days
194.8
respectively.
Conclusion
Children
CRP
≥
IL-6
≤4.5
days,
mg/L
FluA
a
significantly
increased
It
is
useful
clinicians
determine
adjust
treatment
plan,
reduce
incidence
critically
ill
patients.
Language: Английский