Mindfulness-based Real-time fMRI Neurofeedback for Depressed Adolescents: A Randomized Controlled Dosing Trial DOI Open Access
Jiahe Zhang, Paul A. Bloom, David Pagliaccio

et al.

Published: May 23, 2024

Depression is highly prevalent and lacks effective treatment for ~50% of adolescents. Rumination increases the severity duration depressive symptoms characterized by increased activation within default mode network (DMN), which includes core midline hubs medial prefrontal cortex posterior cingulate cortex. We developed a mindfulness-based real-time fMRI neurofeedback (mbNF) protocol to facilitate mindfulness acquisition through downregulating DMN activation. A proof-of-concept study demonstrated that one 15-minute session mbNF was feasible in this population, reduced within-DMN functional connectivity, state mindfulness. The current randomized controlled dosing trial has two main aims. First, we aim test target engagement hypothesize decreases connectivity following among depressed Second, dosage 30- versus dose will lead greater engagement. further explore whether there are reductions rumination mbNF.

Language: Английский

Neuroimaging for precision medicine in psychiatry DOI
Leanne M. Williams,

Susan Gabrieli

Neuropsychopharmacology, Journal Year: 2024, Volume and Issue: 50(1), P. 246 - 257

Published: July 22, 2024

Language: Английский

Citations

5
Bridging Psychedelic VR and BCI: Enhancing User Experience through Adaptive EEG-Guided Neural Modulation DOI
Leon Lange, Jacob Yenney, Ying Choon Wu

et al.

Published: Feb. 25, 2025

Language: Английский

Citations

0
Effect of Qi-based mindfulness therapy for mild-to-moderate depression DOI

Q Li,

Yan Yang, Xuejiao Gao

et al.

World Journal of Psychiatry, Journal Year: 2025, Volume and Issue: 15(4)

Published: March 25, 2025

BACKGROUND Depression is a disorder characterized by significant and persistent depressed mood, cognitive impairment, impaired voluntary activity, working memory, somatic symptoms. AIM To determine the efficacy of Qi-based mindfulness therapy (QMT) in treating anxiety, depression, sleep disturbances individuals with mild-to-moderate depression. METHODS A self-controlled before–after trial was conducted. The study invited online participants for recruitment between May July 2023. Participants (n = 18) aged 18-65 years who were receiving QMT training 4 weeks, included. primary indicators 17 Hamilton Rating Scale Anxiety scores. secondary outcome included Zung Self-rating Scale, self-rating Insomnia Severity Index. Pre- post-intervention assessments patients’ symptoms related to insomnia reassessed weeks after evaluation. RESULTS Patients underwent intervention exhibited statistically reduction scores on Self-Rating Index relative their pre-intervention (all P < 0.05). CONCLUSION an effective nonpharmacological treatment among patients

Language: Английский

Citations

0
Targeting the superior temporal gyrus with real-time fMRI neurofeedback: A pilot study of the indirect effects on self-referential processes in schizophrenia DOI Creative Commons
Francesca Morfini, Clemens Bauer, Jiahe Zhang

et al.

Schizophrenia Research, Journal Year: 2024, Volume and Issue: 270, P. 358 - 365

Published: July 4, 2024

Individuals with schizophrenia (SZ) and auditory hallucinations (AHs) display a distorted sense of self self-other boundaries. Alterations activity in midline cortical structures such as the prefrontal cortex (mPFC) anterior cingulate (ACC) during self-reference well superior temporal gyrus (STG) have been proposed neuromarkers SZ AHs.

Language: Английский

Citations

3
Mindfulness-based Neurofeedback: A Systematic Review of EEG and fMRI studies DOI Creative Commons
Isaac N. Treves, Keara D. Greene, Zia Bajwa

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 15, 2024

Neurofeedback concurrent with mindfulness meditation may reveal effects on the brain and facilitate improved mental health outcomes. Here, we systematically reviewed EEG fMRI studies of neurofeedback (mbNF) followed PRISMA guidelines. We identified 10 reports, consisting 177 unique participants, 9 242 participants. Studies focused primarily downregulating default-mode network (DMN). Although found decreases in DMN activations during neurofeedback, there is a lack evidence for transfer effects, majority did not employ adequate controls, e.g. sham neurofeedback. Accordingly, have been confounded by general task-related deactivation. typically examined alpha, gamma, theta frequency bands, most robust supporting modulation band activity. Both mbNF implemented high fidelity clinical populations. However, benefits established. In general, would benefit from sham-controlled RCTs, as well clear reporting (e.g. CRED-NF).

Language: Английский

Citations

3
Closed-Loop Systems and Real-Time Neurofeedback in Mindfulness Meditation Research DOI Creative Commons

J Chen,

David A. Ziegler

Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

Language: Английский

Citations

1
Mindfulness-based Real-time fMRI Neurofeedback for Depressed Adolescents: A Randomized Controlled Dosing Trial DOI Open Access
Jiahe Zhang, Paul A. Bloom, David Pagliaccio

et al.

Published: May 23, 2024

Depression is highly prevalent and lacks effective treatment for ~50% of adolescents. Rumination increases the severity duration depressive symptoms characterized by increased activation within default mode network (DMN), which includes core midline hubs medial prefrontal cortex posterior cingulate cortex. We developed a mindfulness-based real-time fMRI neurofeedback (mbNF) protocol to facilitate mindfulness acquisition through downregulating DMN activation. A proof-of-concept study demonstrated that one 15-minute session mbNF was feasible in this population, reduced within-DMN functional connectivity, state mindfulness. The current randomized controlled dosing trial has two main aims. First, we aim test target engagement hypothesize decreases connectivity following among depressed Second, dosage 30- versus dose will lead greater engagement. further explore whether there are reductions rumination mbNF.

Language: Английский

Citations

0