Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: Oct. 18, 2023
Abstract
Background
Vaccination
of
healthcare
workers
(HCWs)
is
pivotal
to
decrease
the
incidence
contagious
infections
in
hospital
settings.
Herein,
we
assessed
knowledge,
attitude,
and
practice
regarding
HCWs’
recommended
vaccines
among
medical
students
interns
Egypt.
Methods
A
multicenter,
cross-sectional
study
was
conducted
using
a
structured,
pilot-tested,
self-administered
questionnaire
Egyptian
interns.
We
invited
1332
participants
our
survey
systematic
random
sampling
that
included
across
nine
schools
Egypt
during
2021–2022
academic
year.
Result
Out
participants,
1141
completed
with
response
rate
85.7%.
Overall,
43%
knew
2–3
HCWs
vaccines.
Furthermore,
36.7%
had
received
booster
dose
at
least
one
last
10
years
only
6.1%
having
all
Hepatitis
B
vaccine
most
widely
known
(71%)
(66.7%).
Interns
were
more
likely
know,
receive,
recommend
The
majority
(>
90%)
agreed
vaccination
beneficial
safe,
median
score
eight
(interquartile
range
[IQR]:
2)
out
ten
concerning
efficacy
(IQR:
1)
for
safety.
However,
hesitancy
five
5).
common
influential
limiting
factors
taking
scientific
facts
(60.1%)
fear
side
effects
(44.9%),
respectively.
Conclusion
Although
have
good
knowledge
attitudes
toward
vaccinations,
there
gap
their
practices.
Interventions
are
needed
improve
uptake
vaccinations
International Journal of MS Care,
Journal Year:
2025,
Volume and Issue:
27(Q1), P. 74 - 81
Published: March 10, 2025
Until
the
World
Health
Organization
declared
an
end
to
COVID-19
as
a
global
health
emergency
worldwide
in
2023,
people
with
multiple
sclerosis
(MS)
were
hesitant
get
vaccine.
This
study
aimed
assess
final
vaccination
status,
attitude,
and
adverse
events
related
vaccine
among
MS
Egypt.
A
self-administered
survey
was
offered
who
came
Alexandria
University
Clinic
Egypt
between
June
2023
November
2023.
Of
150
surveys
completed,
77%
of
participants
women.
Their
median
age
35.5
years
(range,
19-59
years);
their
disease
duration
4
years.
Only
81
(54%)
received
that
81,
81.5%
2
doses.
The
fear
score
(FCV-19S)
11,
15.3%
had
high
levels
fear.
Worrying
about
worsening
effect
on
(69.3%)
long-term
(AEs)
vaccines
(63.3%)
most
common
causes
only
factor
significantly
receiving
FCV-19S
(P
=
.049).
Among
those
vaccine,
fatigue
AE
reported
48%;
5%
neurological
relapse.
No
other
serious
AEs
occurred.
In
this
study,
almost
half
did
not
receive
vaccination,
mainly
due
attributed
mild.
Implementing
educational
programs
during
future
pandemics
will
be
necessary
improve
rates
MS.
International Journal of Environmental Research and Public Health,
Journal Year:
2025,
Volume and Issue:
22(2), P. 314 - 314
Published: Feb. 19, 2025
Despite
scientific
breakthroughs
in
vaccine
development,
some
people
remain
reluctant
to
accept
the
anti-SARS-CoV-2
vaccine.
This
study
evaluates
attitudes
and
behaviours
towards
factors
associated
with
refusal/hesitancy
at
start
of
Italy's
vaccination
campaign.
EPICOVID19
is
a
two-phase
observational
web-based
where
adult
volunteers
completed
questionnaires
April-June
2020
January-February
2021.
Refusal/hesitancy
was
assessed
among
those
not
yet
vaccinated.
We
analysed
by
applying
multivariate
multinomial
logistic
regression
models.
Among
36,820
survey
participants
(mean
age
51
years,
59.7%
women,
63.6%
highly
educated),
2449
(6.7%)
were
against
or
hesitant,
4468
(12.1%)
inclined
but
unsure,
29,903
(81.2%)
willing
be
Factors
positively
included
female
sex,
middle
age,
at-risk
occupations,
medium
low
education,
deprived
status,
being
underweight,
previous
SARS-CoV-2
positivity,
poor
perceived
health,
no
fear
contracting
SARS-CoV-2,
contaminated
food
natural
disasters,
trust
science,
media,
government,
institutions.
Low
hesitancy
student
retired
overweight
obesity,
moderate
high
alcohol
consumption,
concern
about
economic
working
conditions,
sensitivity
climate
change/environmental
pollution
epidemics.
showed
that,
during
first
month
campaign,
individuals
receive
highlights
potential
target
groups
for
tailored
communication
prevention
campaigns.
Vaccines,
Journal Year:
2025,
Volume and Issue:
13(3), P. 269 - 269
Published: March 4, 2025
Background/Objectives:
Over
the
past
50
years,
developing
new
vaccines
has
been
pivotal
in
responding
to
emerging
and
re-emerging
diseases
globally.
However,
despite
substantial
partner
support,
introducing
sub-Saharan
Africa
remains
challenging.
This
systematic
review
documents
barriers
vaccine
introduction
by
distinguishing
between
integrated
into
routine
immunization
programs
those
introduced
primarily
for
outbreak
response.
Methods:
A
comprehensive
electronic
search
was
conducted
across
five
databases
articles
published
English
or
French
on
challenges
of
Africa.
Three
reviewers
screened
independently
based
titles
abstracts,
with
full-text
assessments
inclusion.
Data
were
analyzed
thematically
synthesized
narratively.
Results:
total
796
retrieved
from
databases.
Following
screening,
33
finally
retained
included
review.
These
concerned
eight
(malaria
vaccine,
COVID-19
HPV
Ebola
cholera
hepatitis
B
rotavirus
typhoid
vaccine).
The
analyses
revealed
coordination
financing
six
seventeen
countries,
acceptability
ten
logistical
two
quality
service
delivery
three
thirteen
countries.
Conclusions:
Addressing
requires
targeted,
evidence-based
strategies.
Prioritizing
political
commitment,
innovative
funding,
public
education,
workforce
development,
infrastructure
improvements
will
strengthen
systems
enable
timely
delivery.
Collaborative
efforts
a
focus
local
context
can
advance
equitable
health
outcomes,
safeguard
health,
support
global
goals.
Human Vaccines & Immunotherapeutics,
Journal Year:
2025,
Volume and Issue:
21(1)
Published: March 9, 2025
Fear
of
side
effects
is
the
main
motive
for
vaccine
refusal.
However,
before
COVID-19
pandemic,
little
attention
had
been
paid
to
actual
experience
adverse
events
and
its
relationship
with
hesitancy.
This
scoping
review
aimed
analyze
impact
VH
on
EAE
vice
versa.
We
reviewed
55
articles.
Most
studies
focused
vaccination
employed
cross-sectional
surveys
self-reported
indicators.
These
identified
significant
correlations
between
VH.
Social
cognitive
models
shed
some
light
influence
VH,
while
converse
usually
explained
by
nocebo
effect
that
predominately
accounts
converse.
emerging
research
field
hampered
inconsistencies
in
theoretical
explanations,
assessments
relationship,
measurements
these
two
phenomena.
A
more
comprehensive
consideration
individual
experience,
both
objective
subjective,
would
help
develop
effective
communication
strategies
improve
pharmacological
surveillance.
Egyptian Pediatric Association Gazette,
Journal Year:
2023,
Volume and Issue:
71(1)
Published: Dec. 4, 2023
Abstract
Background
Vaccination
against
severe
acute
respiratory
distress
syndrome
coronavirus
2
(SARS-CoV-2)
has
gained
recognition
as
a
crucial
strategy
to
prevent
and
reduce
the
risk
of
infection,
including
emerging
variants,
due
its
proven
safety,
immunogenicity,
effectiveness.
This
study
aimed
evaluate
vaccination
hesitancy
(VH)
among
Egyptian
parents
towards
SARS-CoV-2
vaccination,
specifically
focusing
on
with
chronically
ill
children.
Method
A
multicentered
cross-sectional
survey
was
conducted
at
outpatient
clinics
El-Raml
Pediatric
Hospital,
Ministry
Health
Population
(MOHP)
in
Alexandria,
Alexandria
Main
University
Hospital
for
Maternity
Children
(AMUH),
Al-Galaa
Teaching
General
Organization
Hospitals
Institutes
(GOTHI)
Cairo,
Department,
Menoufia
from
May
1
st
till
December
15
th
,
2022.
Parents
children
chronic
diseases
were
recruited
using
simple
random
sampling
technique
respond
validated
Arabic
version
parental
attitudes
about
childhood
(PACV).
Results
In
this
study,
we
enrolled
527
caregivers,
55.4%
them
aged
30–39
years
old,
85.2%
females,
46.9%
had
diseases.
Commonly
mentioned
information
sources
included
television
radio
(69.8%),
social
media
(35.3%).
Among
studied,
59.6%
refused
vaccination.
The
predictors
PACV
score
governorate,
(β
=
11.30,
95%CI
[5.32,
17.27],
p
<
0.001),
setting,
-20.07,
[-25.40,
-14.75]
-10.74,
[-14.50,
-6.98],
income;
not
enough
loans
repaid
3.18,
[0.54,
5.82],
0.018)
3.57,95%CI
[0.08,
7.07],
0.045).
Conclusions
reveals
geographic
economic
factors
PACV,
emphasizes
need
region-specific
interventions
financial
barriers
improve
vaccine
acceptance
child
well-being.
BMJ Open,
Journal Year:
2023,
Volume and Issue:
13(12), P. e076184 - e076184
Published: Dec. 1, 2023
Objective
The
study
sought
to
explore
the
perspectives
of
vaccinators
on
health
system
factors
that
impacted
COVID-19
vaccination
campaign.
Design
employed
an
exploratory-descriptive
qualitative
design.
Key-informants’
interviews
were
conducted
using
semi-structured
guide
gather
data.
Thematic
analysis
following
steps
Braun
and
Clark
was
ATLAS.ti
software.
Setting
setting
Cape
Coast
Metropolis
where
Central
Regional
Health
Directorate
is
located.
initiates
implements
policy
decisions
across
region.
It
also
only
metropolis
in
region
recorded
about
5970
total
cases
Ghana.
Participants
Eleven
who
had
been
trained
for
participated
campaign
at
least
6
months
purposively
sampled
through
Public
Unit.
Results
Four
themes
derived
from
data
after
analysis;
‘vaccine-related
issues’;
‘staffing
‘organising
planning
campaign’
‘surveillance
response
systems’.
Subthemes
generated
under
each
major
theme.
Our
results
revealed
service
promoted
public
education
ensured
access
vaccines
use
community
outreaches.
Also,
adequate
logistics
supply
carrying
out
as
well
adequately
equipped
adverse
incidence
reporting
management.
Dissatisfaction
among
attributed
low
remuneration
delays
receiving
allowances
shortfalls
efforts
securing
transportation
a
conducive
venue
exercise
emerged.
Other
challenges
poor
entry
platforms
limited
internet
facilities.
Conclusion
This
highlights
system’s
strategies
during
campaign,
emphasising
need
critical
interventions
prevent
rates.
Diseases,
Journal Year:
2024,
Volume and Issue:
12(6), P. 113 - 113
Published: May 24, 2024
Background:
As
mortality
declined
significantly
during
the
fourth
and
fifth
waves
compared
to
previous
waves,
question
of
future
role
COVID-19
vaccination
arose
among
both
experts
public
in
South
Africa.
Turning
attention
away
from
general
public,
now
considered
be
at
very
low
risk
severe
disease,
a
commonly
held
view
was
that
campaign
should
focus
only
on
those
who
remain
highly
vulnerable
disease
death
COVID-19.
Primary
amongst
this
group
are
patients
with
common
chronic
diseases
attending
hospital
outpatient
departments.
We
hypothesized
providing
vaccinations
on-site
central
will
increase
uptake
for
co-morbid
conditions
need
them
most
Omicron
phase
pandemic.
Aim:
Evaluate
acceptability,
need,
hospital-based
site
medical
Objectives:
To
assess
uptake,
coverage,
hesitancy
people
hospital,
determine
factors
associated
influencing
document
implementation
acceptability
project
staff
persons
hospital.
Methods:
Mixed-methods
study
using
quantitative
qualitative
methods.
Results:
Of
317
participants
enrolled
study,
229
(72%)
had
already
received
least
one
dose
vaccine.
A
total
296
were
eligible
first
vaccination,
additional
or
booster
according
African
Department
Health
guidelines.
previously
vaccinated,
65%
opted
an
day
it
offered
(same
day).
Only
13
unvaccinated
(15%
vaccine
naïve
participants)
increasing
coverage
72%
76%.
Approximately
24%
(n
=
75)
all
refused
(vaccine
hesitant).
Variables
tested
association
status
demonstrated
age
reached
statistical
significance.
Emerging
themes
analysis
included
perceptions
vulnerability,
safety
efficacy
concerns,
information
gaps
regarding
vaccinations,
value
convenience
decision
vaccinate,
health
promoters.
Conclusions:
This
has
shown
is
logistically
acceptable
provide
large
targeting
services
conditions.
service
also
benefits
accompanying
staff.
Access
influence
decision-making,
opportunity
vaccinate.
However,
widespread
just
under
one-quarter
remaining
unvaccinated.
Strengthening
education
patient–clinician
engagement
about
essential
reach
populations
routinely
departments
appropriate
program.
BMC Medical Education,
Journal Year:
2024,
Volume and Issue:
24(1)
Published: Aug. 14, 2024
Abstract
Background
Vaccination
of
healthcare
workers
(HCWs)
is
pivotal
in
decreasing
the
incidence
contagious
infections
hospital
settings.
In
this
study,
we
assessed
knowledge,
attitude,
and
practice
regarding
HCWs’
recommended
vaccines
among
medical
students
interns
Egypt.
Methods
A
multicenter,
cross-sectional
study
was
conducted
using
a
structured,
pilot-tested,
self-administered
questionnaire
Egyptian
interns.
We
invited
1332
participants
to
our
survey
systematic
random
sampling
that
included
across
nine
schools
Egypt
during
2021–2022
academic
year.
Results
Out
participants,
1141
completed
with
response
rate
85.7%.
Overall,
43%
had
intermediate
knowledge
(knew
2–3
vaccines).
Furthermore,
36.7%
received
booster
dose
at
least
one
over
last
10
years,
only
6.1%
having
all
vaccines.
Hepatitis
B
vaccine
most
widely
known
(71%)
(66.7%).
Interns
were
more
likely
know,
receive,
recommend
The
majority
(>
90%)
agreed
vaccination
beneficial
safe,
median
score
eight
(interquartile
range
[IQR:
Q25-Q75]:
7–9)
out
ten
for
efficacy
(IQR:
7–8)
safety.
However,
hesitancy
five
2–7).
common
influential
limiting
factors
scientific
facts
(60.1%)
fear
side
effects
(44.9%).
Conclusion
Although
have
good
attitudes
towards
vaccination,
there
gap
their
practices.
Interventions
are
needed
improve
uptake
Journal of the Egyptian Public Health Association,
Journal Year:
2024,
Volume and Issue:
99(1)
Published: Nov. 17, 2024
Abstract
Background
Vaccine
confidence
is
described
as
a
belief
that
vaccines
are
effective,
safe,
and
part
of
trustworthy
health
system.
The
objective
this
study
was
to
develop
validate
an
Arabic
tool
evaluate
in
the
received
coronavirus
disease
2019
(COVID-19)
(ARAB-VAX-CONF).
Methods
research
team
developed
ARAB-VAX-CONF
based
on
three
areas
specified
by
Centers
for
Disease
Control
Prevention
(CDC):
vaccine
effectiveness,
safety,
healthcare
analysis
includes
data
from
406
eligible
vaccinated
persons
(≥
18
years).
Cronbach’s
alpha
used
measure
internal
consistency,
while
convergent,
discriminant,
exploratory,
confirmatory
factor
analyses
were
verify
construct
validity.
Results
A
total
adults
recruited,
with
mean
age
33.0
±
12.2
years.
63.1%
males,
56.7%
married,
21.9%
had
chronic
conditions,
93.3%
nonsmokers,
39.6%
obligated
obtain
vaccines.
domains
scale
met
criterion
consistency
(Cronbach’s
>
0.7).
Convergent
validity
identified
significant
inter-item
item-mean
score
domain
correlation
(
P
<
0.001).
Discriminant
reported
inter-factor
matrix
(<
Kaiser–Meyer–Olkin
sampling
adequacy
0.80,
Bartlett’s
sphericity
test
Exploratory
indicated
could
be
summarized
into
factors.
Confirmatory
confirmed
adequate
psychometric
properties
fit
observed
(root-mean-square
error
approximation
=
0.08,
comparative
index
0.945,
Tucker-Lewis
0.924,
standardized
root-mean-square
residual
0.086,
normed
0.918,
goodness-of-fit
0.909).
Conclusions
valid
reliable
assessing
can
support
decision-makers
addressing
gap
among
various
populations.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 4, 2024
Abstract
Background
Vaccination
of
healthcare
workers
(HCWs)
is
pivotal
to
decrease
the
incidence
contagious
infections
in
hospital
settings.
Herein,
we
assessed
knowledge,
attitude,
and
practice
regarding
HCWs’
recommended
vaccines
among
medical
students
interns
Egypt.
Methods
A
multicenter,
cross-sectional
study
was
conducted
using
a
structured,
pilot-tested,
self-administered
questionnaire
Egyptian
interns.
We
invited
1332
participants
our
survey
systematic
random
sampling
that
included
across
nine
schools
Egypt
during
2021–2022
academic
year.
Result
Out
participants,
1141
completed
with
response
rate
85.7%.
Overall,
43%
knew
2–3
HCWs
vaccines.
Furthermore,
36.7%
had
received
booster
dose
at
least
one
last
10
years
only
6.1%
having
all
Hepatitis
B
vaccine
most
widely
known
(71%)
(66.7%).
Interns
were
more
likely
know,
receive,
recommend
The
majority
(>
90%)
agreed
vaccination
beneficial
safe,
median
score
eight
(interquartile
range
[IQR]:
2)
out
ten
concerning
efficacy
(IQR:
1)
for
safety.
However,
hesitancy
five
5).
common
influential
limiting
factors
taking
scientific
facts
(60.1%)
fear
side
effects
(44.9%),
respectively.
Conclusion
Although
have
good
knowledge
attitudes
toward
vaccinations,
there
gap
their
practices.
Interventions
are
needed
improve
uptake
vaccinations
